Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi

Seyit Köse

doi:10.17343/sdutfd.67496

Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi

Abstract

Polikistik over sendromu, üreme çağındaki kadınların % 3-4'ünü etkiler. Hirsutizm yakınması olanların % 70'inde polikistik over sendromu bulunmaktadır. Laparoskopik Ovaryan Drilling (LOD) polikistik over sendromunun tedavisinde yıllardır uygulana gelen ve hala gelecek vaat eden bir tedavi yöntemidir. Bununla birlikte LOD sonrasında % 85 hastada postoperatif adezyon oluşumu potansiyel komplikasyon olarak görülmüştür. Bu çalışmada yeni bir laparoskopk aletin preliminer sonuçları sunulmaktadır. Elektrik akımının kullanılmadığı bu yeni teknikle anovulasyonu olan polikistik over sendromu hastaları daha az travma ve daha az postoperatif yapışıklıkla tedavi edilebilir. Çalışmada, polikistik over sendromu olan hastaların endokrin değişiklikleri ve hirsutizm ve adet düzeni gibi periferik yansımaları değerlendirilmek amaçlanmıştır. Anahtar Kelimeler: Polikistik over sendromu, Laparoskopik Ovaryan Drilling (LOD), Laparoskopik Ovaryan Multineedle Intervention (LOMNI) The Effect of Laparoscopic Ovarian Multineedle Intervention (LOMNI) Method on Hirsutism, Menstruation Cycle and Blood Hormon Levels in Patients With Polycystic Ovary Syndrome Abstract: Polycystic ovary syndrome affects about 3 – 4 % of the total women population in active reproductive period and this syndrome is also present in 70 % of people with hirsutism complaint. Laparoscopic ovarian drilling method is still widely in use for years in polycystic ovary syndrome treatment and also promises for the future. However post – operative adhesion formation has been observed in 85 % of patients as a potential complication. In this study, we present the preliminary results of a new laparoscopic tool which has been specially designed by us. Anovulatory patients with policystic ovary syndrome can be treated with less trauma and post – operative adhesion complication with this new method, in which the electricity is not used. In the present study, we aimed to evaluate the hormonal changes and other reflections of these changes like hirsutism and menstrual cycle disorders in patients with polycystic ovary syndrome. Keywords: Polycystic ovary syndrome, laparoscopic ovarian drilling, laparoscopic ovarian multineedle intervention (LOMNI).

Keywords

Polikistik over sendromu, Laparoskopik Ovaryan Drilling (LOD), Laparoskopik Ovaryan

References

Farquhar CM, Vandekerckhove P, Arnot M, Lilford R. Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. Cochrane Database Sys Rev 2000; (CD001122)
Amin AF, Abd el-Aal DE, Derwish AM, Meki AR. Evaluation of the impact of laparoscopic ovarian drilling on Doppler indices of ovarian stromal blood flow, serum vascular endothelial growth factor, insulin-like growth factor-1 in women with polycystic ovary syndrome. Fertil Steril. 2003; (79): 938-41
Gurgan T, Kisnisci H, Yaralý H, Develioðlu O, Zeyneloðlu H, Aksu T. Evaluation of adhesions formation after laparoscopic treatment of polycystic ovarian disease. Fertil Steril. 1991; (56): 1176-78
Tulandi T, Watkin K, Tan SL. Reproductive performans and thrre-dimensional ultrasound volume determination of polycystic ovaries following laparoscopic ovarian drilling. Int J Fertil Womens Med. 1997; (42): 436-40
Ozkaya O, Kaya H, Sezik M, Akyurek C, Ozbasar D. The value of labaratory tests and ultrasonography in evaluating ovarian response to ovulation induction treatment with low-dose recombinant follicle- stimülating hormone. Int J Fertil Womens Med. 2004; (49): 83-7
Amer SA, Gopalan V, Li TC, Ledger WL, Cooke ID. 13
Long term follow-up of patients with polycystic ovarian syndrome after laparoscopic ovarian drilling: Clinical outcome. Hum Reprod. 2002; (17): 2035-42
Dabirashrafi H, Mohammed K, Behjatnia Y, Moghadami-Tabrizi N. Adhesion formation after ovarian electrocauterization on patients with polycystic ovarian syndrome. Fertil Steril. 1991; (55): 1200-01

Farquhar CM, Birdsall M, Manning P, et al. The prevelance of polycystic ovaries on ultrasound scanning in a population of randomly selected women. Aust N Z J Obstet Gynaecol. 1994; (34): 67-72
Atiomo WU, Pearson S, Shaw S, Pantice A, Dubbins P. Ultrasound criteria in the diagnosis of polycystic ovary syndrome (PCOS). Ultrasound Med Biol. 2000; (26): 977-80
Gjonnaess H. Late endocrine effets of ovarian electrocautery in women with polycystic ovary syndrome. Fertil Steril. 1998; (69): 697-701
Armar NA, Mc Gaarrigle HH, Honour J, et al. Laparoscopic ovarian diathermy in the management of anovulatory infertility in women with polycystic ovaries: endocrine changes and clinical outcome. Fertil Steril. 1990; (53): 5-9
Gjonnaess H. Polycystic ovarian syndrome treated by ovarian electrocautery through the laparoscope. Fertil Steril. 1984; (41): 20-5
Poretsky L, Clemon J, Bogovich K. Hyperinsulinemia and human chorionic gonadotropin synergistically promote the growth of ovarian follicular cysts in rats. Metabolism. 1992; (41): 903-910
Felemban A, Lin Tan S, Tulandi T. Laparoscopic treatment of polycystic ovaries with insulated needle cautery: a reappraisal. Fertility and Sterility. 2000; (73),(2): 266-69
Li TC, Saravelos H, Chow MS, Chisabingo R, Cooke ID. Factors affecting the outcome of laparoscopic ovarian drilling for polycystic ovarian syndrome in women with anovulatory infertility. Br J Obstet Gynaecol. 1998; (105): 338-44
Farhi J, Soule S, Jacobs HS. Effect of laparoscopic ovarian electrocautery on ovarian response and outcome of treatment with gonadotropins in clomiphene citrate- resistant patients with polycystic ovary syndrome. Fertil Steril. 1995; (64): 930-35
Amer SA, Gopalan V, Li TC, Ledger WL, Cooke ID. Long term follow-up of patients with polycystic ovarian syndrome after laparoscopic ovarian drilling: Clinical outcome. Hum Reprod. 2002; (17): 2035-42
Sakata M, Tasaka K, Kurachi H, Terakawa N, Miyake, et al. Changes of bioactive luteinizing hormone after laparoscopic ovarian cautery in patients polycystic ovarian syndrome. Fertil Steril. 1990; (53): 10-13.
Lemieux S, Lewis GF, Ben Chetrit A. Correction of hyperandrogenemia by laparoscopic ovarian cautery in women with polycystic ovarian syndrome is not accompained by improved insulin sensitivity or lipid- lipoprotein levels. J Clin Endocrinol Metab. 1999; (84): 4278-82
Gjonnaess H. Comparison of ovarian electrocautery and oral contraceptives in the treatment of hyperandrogenizm in women with polycystic ovary syndrome. Acta Obstet Gynaecol Scand. 1999; (78), (6): 530-33.
Kaya H, Sezik M, Ozkaya O. Evaluation of a new surgical approach for the treatment of clomiphene citrate-resistant infertility in polycystic ovary syndrome: laparoscopic ovarian multi-needle intervention. 2005; (12): 355-58.
Farquhar C, Lilford RJ, Marjoribanks J, Vandekerckhover P. Laparoscopic drilling by diathermy or laser for ovulation induction in anovulatory polycystic ovary syndrome. Cochrane Database Sys Rev 2007.

Details

Primary Language

Turkish

Subjects

-

Journal Section

-

Authors

Seyit Köse

Publication Date

June 30, 2010

Submission Date

March 5, 2010

Acceptance Date

-

Published in Issue

Year 2010 Volume: 17 Number: 2

DOI

https://doi.org/10.17343/sdutfd.67496

IZ

https://izlik.org/JA76DN38GF

Cite

RIS / Bibtex

APA

Köse, S. (2010). Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi. Medical Journal of Süleyman Demirel University, 17(2), 8-13. https://doi.org/10.17343/sdutfd.67496

AMA

1.Köse S. Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi. Med J SDU. 2010;17(2):8-13. doi:10.17343/sdutfd.67496

Chicago

Köse, Seyit. 2010. “Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) Yönteminin Hirsutizm, Adet Düzeni Ve Hormon Düzeylerine Etkisi”. Medical Journal of Süleyman Demirel University 17 (2): 8-13. https://doi.org/10.17343/sdutfd.67496.

EndNote

Köse S (June 1, 2010) Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi. Medical Journal of Süleyman Demirel University 17 2 8–13.

IEEE

[1]S. Köse, “Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi”, Med J SDU, vol. 17, no. 2, pp. 8–13, June 2010, doi: 10.17343/sdutfd.67496.

ISNAD

Köse, Seyit. “Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) Yönteminin Hirsutizm, Adet Düzeni Ve Hormon Düzeylerine Etkisi”. Medical Journal of Süleyman Demirel University 17/2 (June 1, 2010): 8-13. https://doi.org/10.17343/sdutfd.67496.

JAMA

1.Köse S. Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi. Med J SDU. 2010;17:8–13.

MLA

Köse, Seyit. “Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) Yönteminin Hirsutizm, Adet Düzeni Ve Hormon Düzeylerine Etkisi”. Medical Journal of Süleyman Demirel University, vol. 17, no. 2, June 2010, pp. 8-13, doi:10.17343/sdutfd.67496.

Vancouver

1.Seyit Köse. Polikistik Over Sendromlu Hastalarda Laparoskopik Ovaryan Multineedle Intervention (LOMNI) yönteminin Hirsutizm, Adet Düzeni ve Hormon Düzeylerine Etkisi. Med J SDU. 2010 Jun. 1;17(2):8-13. doi:10.17343/sdutfd.67496