Eosinophilic Gastrointestinal Disorders

Abstract

Eosinophilic Gastrointestinal Disorders are caused by excessive levels of eosinophils in various parts of the gastrointestinal tract. There are several subcategories of eosinophilic gastrointestinal disorders including eosinophilic esophagitis, eosinophilic gastroenteritis and eosinophilic colitis. These diseases has become increasingly recognized recently in both pediatric and adult populations. Symptoms of eosinophilic gastrointestinal disorders are nausea, vomiting, diarrhea, abdominal pain, poor growth or weight loss and dysphagia. Main therapeutic options are steroids and dietary modification. In this article we tried to review eosinophilic gastrointestinal diseases under the highlight of the recent studies

Keywords

• Eosinophil
• gastrointestinal
• inflammation
• pathogenesis
• therapy

Eosinofilik gastrointestinal hastalıklar

Abstract

Eosinofilik gastrointestinal hastalıklar sindirim sisteminin farklı bölümlerinde fazla miktarda eosinofil birikimiyle karekterizedir. Eosinofilik gastrointestinal hastalıklar tutulum bölgesine göre eosinofilik özefajit, eosinofilik gastroenterit ve eosinofilik kolit olarak alt kategorilere ayrılır. Bu hastalıklar hem çocuk hem de erişkin populasyonunda gittikçe artan bir sıklıkta tanı almaktadırlar. Tipik olarak 3. ve 5. dekatlarda görülmektedir. Eosinofilik gastrointestinal hastalıkların semptomları çeşitlidir ama bulantı, kusma, karın ağrısı, kilo kaybı ya da gelişme geriliği ve yutkunma zorluğu vardır. Ana tedavi seçeneklerini steroidler ve diyet değişiklikleri içerir. Bu yazıda son çalışmalar ışığında eozinofilik gastrointestinal hastalıklar gözden geçirildi.

Keywords

• eozinofil
• gastrointestinal
• inflamasyon
• patogenez
• tedavi

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