Primary testicular lymphoma: report of five cases and review of the literature

Abstract

Primary testicular lymphoma: report of five cases and review of the literaturePrimary testicular lymphoma (PTL) comprises around 3- 9% of testicular cancers and 1-2% of all non-Hodgkinlymphomas. It is the most common testicular malignancy in men aged over 60 years. The most commonhistological subtype is diffuse large B-cell lymphoma. It usually presents as a painless unilateral testicularmass and swelling. Scrotal pain or lymphocele may also occur. Lymphoma may locally invade the epididymis,spermatic cord, and scrotal skin. At the time of diagnosis or during the course of the disease, spread mayoccur to the extranodal sites, including the contralateral testis, central nervous system, skin, lung,pleura,Waldeyer's ring and soft tissues. Although PTL is rare, testicular involvement of nodal lymphomas is morecommon. In this study we aimed to discuss the clinicopathological features of the cases diagnosed as PTLwith the review of the literature

Keywords

• Primary testicular lymphoma
• diffuse large B cell lymphoma
• treatment

PRİMER TESTİS LENFOMALARI: BEŞ OLGU SUNUMU VE LİTERATÜRÜN GÖZDEN GEÇİRİLMESİ

Abstract

Primer testis lenfomaları testis tümörlerinin yaklaşık %3-9'unu ve tüm non-Hodgkin lenfomaların yaklaşık %1-2'sini oluştururlar. 60 yaşın üstünde en sık görülen testis malignitesidir. En sık görülen histolojik subtip diffüz büyük B hücreli tip lenfomadır. Genellikle tek taraflı ağrısız testiküler kitle ve şişlik izlenir. Skrotal ağrı ve lenfosel oluşabilir. Lenfoma, lokal olarak epididim, spermatik kord ve skrotum derisini invaze edebilir. Tanı anında veya hastalığın seyri sırasında karşı testis, santral sinir sistemi, deri, akciğer, plevra, Waldeyer halkası ve yumuşak dokular gibi ekstranodal bölgelere yayılım görülebilir. Primer testis lenfoması (PTL) nadir olmasına karşın, nodal lenfomaların testis tutulumuna daha sık rastlanır. Bu çalışmada PTL tanısı alan olguların klinikopatolojik bulgularının literatür bilgileri eşliğinde tartışılması amaçlanmıştır.

Keywords

• Primer testis lenfomasý
• diffüz büyük B hücreli lenfoma
• tedavi

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