ADENOİDEKTOMİ YAPILAN HASTALARDA PLATELET-LENFOSİT ORANI

Abstract

Amaç: Bu çalışmada adenoidektomi hastalarında platelet-lenfosit oranının (PLO) prediktif bir faktör olup olmadığının ve adenoid hipertrofisi olan hastalarda platelet-lenfosit oranının sistemik inflamasyonu gösterip göstermediğinin ortaya konulması amaçlandı. Gereç ve Yöntemler: Çalışma grubuna Süleyman Demirel Üniversitesi Tıp Fakültesi Kulak Burun Boğaz Anabilim Dalı’nda (KBB) 2017-2018 yılları arasında adenoid hipertrofisi tanısı alan 3-11 yaşları arasında toplam 100 erkek hasta dahil edilmiştir. Kontrol grubu, Üroloji ve Çocuk Cerrahisi kliniklerinde sünnet edilen 100 sağlıklı erkekten oluşmaktaydı. Hastaların tıbbi kayıtları retrospektif olarak incelendi. Preoperatif laboratuvar parametreleri hasta dosyaları gözden geçirilerek değerlendirildi. Platelet-lenfosit oranı mutlak platelet sayısının mutlak lenfosit sayısına bölünmesi ile elde edildi. Bulgular: Platelet-lenfosit oranı kontrol ve çalışma grupları için sırasıyla 91,68 ve 84,15 idi ve istatistiksel olarak iki grup arasında anlamlı bir fark yoktu. (Mann-Whitney U testi, p=0,062). Mann-Whitney U testi, WBC, platelet ve lenfosit sayılarında çalışma ve kontrol grupları arasında anlamlı bir fark olmadığını gösterdi. (p>0,05). Kontrol grubunda platelet-lenfosit oranı, çalışma grubuna göre daha yüksekti. Sonuç: Platelet ve lenfosit standart sapmalarının çok yüksek olduğunu gözlemledik, bu nedenle adenoidektomide platelet-lenfosit oranının güvenilir bir değer olmadığı kanaatine varıldı. 

Keywords

• Adenoid hipertrofisi,Platelet-Lenfosit Oranı (PLO),Sistemik İnflamasyon

PLATELET-TO-LYMPHOCYTE (PLR) RATİOS İN ADENOİDECTOMY PATİENTS

Abstract

Objective: This study aimed to investigate Platelet-to-lymphocyte (PLR) ratios in adenoidectomy patients to determine whether this ratio can be a possible predictive factor in adenoidectomy. We also aimed to investigate whether PLR can help indicate ongoing systemic inflammation on patients with adenoid hypertrophy. Materials and Methods: A total of 100 boys aged 3-11 years, who had undergone adenoidectomy for adenoid hypertrophy between 2012 and 2018 at Suleyman Demirel University School of Medicine, Department of Ear Nose and Throat (ENT), were assigned to the study group. The control group consisted of 100 healthy boys who had been circumcised in the Urology or Pediatric Surgery Departments. Patients medical records were retrospectively reviewed. The results of preoperative complete blood counts were evaluated by reviewing the patient files. The PLR value is obtained by dividing absolute platelet count by absolute lymphocyte count. Results: PLR were 91,47 and 84,15 for control and study groups respectively with no statistically significant difference (Mann-Whitney U test, p = 0.062). The Mann-Whitney U test showed no significant difference between study and control groups among WBC, platelet and lymphocyte counts (p>0.05). PLR was higher in the control group as compared to the study group. Conclusion: We observed platelet and lymphocyte standard deviations are too high, therefore we beleive that PLR is not a reliable value in adenoidectomy.

Keywords

• Adenoidectomy,Adenoid Hypertrophy,Platelet-to-Lymphocyte Ratio (PLR)

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