Comparison of cervical HPV and smear results in women with genital wart

Abstract

OBJECTIVE: To determine the type of HPV that causes lesion in women with genital warts and to compare them with cervical HPV and cytology samples

MATERIAL AND METHODS: HPV typing and cervical cytology were performed from women who applied to our hospital between April 2014 and April 2015 due to genital warts. The study was a prospective study and approval was obtained from the ethics committee of our hospital and the informed consent was obtained to the women who accepted to participate in the study. Forty women were given to our study.

RESULTS: Our study was carried out on 44 patients whose ages ranged from 17 to 60 years. The mean age of the patients was 35.75 ± 11.67 years. While 17 (38.6%) of the cases were under 30 years of age, 27 (61.4%) were over 30 years of age. In HPV typing in genital lesion, 35 (79.5%) HPV type 6-11 were detected, 3 (6.8%) HPV type 16-18 were detected, and 6 (13.6%) could not have HPV. When the cervical HPV results were examined; 30 (68.2%) HPV type 6-11, 3 (6.8%) HPV type 16-18, 2 (4.5%) HPV other high type were observed, 9 (20.5%) cases were cervical HPV negative. When the cervical cytology of the patients were examined; While 35 (79.5%) smear results were normal, 5 (11.4%) ASCUS and 4 (9.1%) LGSIL were detected.

CONCLUSION: It should be considered that increased risk of cervical HPV and cervical dysplasia in patients presenting with genital warts. Cervical examination should be performed carefully in patients with conduloma, cytological sampling should be taken and colposcopy-guided biopsy should be taken if necessary.

Keywords

• Wart
• HPV
• Smear
• Genital Lesion

Genital siğili olan kadınlarda servikal HPV ve servikal smear sonuçlarının karşılaştırılması

Abstract

AMAÇ: Genital siğili olan kadınlarda lezyona neden olan HPV tipini belirlemek ve bu kadınlarda servikal HPV ile sitoloji örnekleriyle karşılaştırmak

MATERYAL VE METOD: Hastanemize nisan 2014- nisan 2015 tarihleri arasında genital siğil nedeniyle başvuran kadınlardan lezyon üzerinden ve servikal sürüntüden HPV tiplendirilmesi yapılıp servikal sitolojileri incelendi. Çalışma prospektif bir çalışma olup hastanemiz etik kurulundan onay alınmış,  çalışmaya katılmayı kabul eden kadınlara gerekli bilgilendirme yapılarak aydınlatılmış rıza belgesi alınmıştır. Çalışmamıza uygun olup rıza veren 44 kadın incelendi.

BULGULAR: Çalışmamız yaşları 17 ile 60 yıl arasında değişmekte olan toplam 44 olgu üzerinde yapılmıştır. Olguların ortalama yaşları 35.75±11.67 yıldır. Olguların 17’si (%38.6) 30 yaş altında iken, 27’si (%61.4) 30 yaş ve üzerindedir. Genital lezyondan alınan örnekte yapılan HPV tiplendirilmesinde 35 (% 79.5) HPV tip 6-11 izlenirken, 3 (%6.8) HPV tip 16-18 tespit edilmiş, 6 (%13,6) olguda ise HPV tespit edilememiştir. Olguların servikal HPV sonuçları incelendiğinde; 30 (%68.2) HPV tip 6-11 3 (%6.8) HPV tip 16-18 , 2(%4.5) HPV diğer yüksek tip izlenirken, 9 (% 20.5) olguda servikal HPV negatif tespit edildi. Hastaların servikal sitolojileri incelendiğinde; 35 (%79.5) smear sonucu normal iken, 5’inde (%11.4) ASCUS, 4’ünde (%9.1) LGSIL tespit edilmiştir.

SONUÇ: Genital siğil ile başvuran hastalarda servikal HPV ve servikal displazi riskinin artmış olduğu göz önünde bulundurulmalıdır. Kondillomlu hastalarda servikal muayene dikkatlice yapılmalı, sitolojik örnekleme alınmalı ve gerektiğinde kolposkopi eşliğinde biyopsi alınmasını düşünmekteyiz.

Keywords

• Siğil
• HPV
• Smear
• Genital Lezyon

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