COVID-19 ve Sinir Sistemi

Abstract

Nörolojik komplikasyonlar, COVID-19 pandemisinde önemli bir morbidite ve mortalite nedenidir. Birçok hastada solunum yetmezliği dışında; baş ağrısı, baş dönmesi, koku-tat duyusunda azalma, akut serebrovasküler hastalık, ensefalopati, ensefalit tablosu gibi nörolojik bulgular görülmektedir. Bu komplikasyonlar, virüs kaynaklı hiperinflamasyon ve hiperkoagülasyon, merkezi sinir sisteminin doğrudan virüs ile enfeksiyonu ve postenfeksiyöz immün aracılı süreçler gibi çeşitli mekanizmalarla açıklanmaktadır. COVID-19 pandemisi sırasında, spesifik olan veya olmayan nörolojik bulgularla başvuran hastalarda SARS-CoV-2 enfeksiyonu mutlaka hatırlanmalıdır.

Keywords

• COVID-19
• nörolojik bulgular
• pandemi

COVID-19 and the Nervous System

Abstract

Neurologic complications are a significant cause of morbidity and mortality in the COVID-19 pandemic. Besides respiratory disease, neurological manifestations such as headache, dizziness, hyposmia, hypogeusia, acute cerebrovascular disease, encephalopathy, encephalitis are common. These complications may result from various mechanisms; virus-induced hyperinflammation and hypercoagulable states, a direct viral effect on the central nervous system, and post-infectious autoimmunity. We must keep in mind diagnosing SARS-CoV-2 infection when patients present with specific or non-specific neurological symptoms during the pandemic.

Keywords

• COVID-19
• neurologic manifestations
• pandemic

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