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The development of muscular layers in the wall of fetal urinary bladder during the fetal period

Year 2009, Volume 16, Issue 1, 16 - 20, 30.03.2009

Abstract

Süleyman Demirel Üniversitesi TIP FAKÜLTESİ DERGİSİ: 2009 Mart; 16 (1) The development of muscular layers in the wall of fetal urinary bladder during the fetal period Neslihan Cankara, Gülnur Özgüner, Esra Koyuncu, Kadir Desdicioðlu, Osman Sulak Özet Fetal dönem boyunca fetal mesane duvarýndaki kas tabakalarýnýn geliþimi Amaç: Çalýþmamýzda fetal dönem boyunca mesane duvarýnýn kas tabakalarýnýn geliþimi incelenmiþtir. Gereç ve Yöntem: Bu çalýþma, gestasyonel yaþlarý 9-40. haftalar arasýnda deðiþen 130 insan fetusu üzerinde yapýldý. Ýlk olarak mesane, pelvis boþluðundaki yerinden çýkarýldý. Daha sonra, mesane corpusunun ön duvarýndan örnekler alýndý. Rutin histolojik doku takip yöntemlerinden sonra, alýnan örnekler parafine gömüldü, parafin bloklardan 5 ìm.lik seri kesitler alýndý ve kesitler hematoksilen-eozin ile boyandý. Iþýk mikroskobunda total duvar kalýnlýðý, longitudinal ve sirküler kas tabakalarýnýn kalýnlýklarý ölçüldü. Bulgular: Elde edilen veriler deðerlendirildiðinde, parametrelerde cinsler arasýnda fark olmadýðý gözlendi (p>0.05). Tüm parametrelerin gestasyonel yaþla birlikte arttýðý tespit edildi (p<0.001). 1. trimesterde vakalarýn %33.ü iki tabakalý kas yapýsýna sahip iken, %67.sinde üç tabakalý kas yapýsý mevcuttu. Ýkinci trimesterde vakalarýn %86.sýnda, 3. trimesterde %97.sinde ve full term.de ise tamamýnda üç tabakalý kas yapýsý gözlendi. Ýki tabakalý kas yapýsýna ait olgularýn yüzde daðýlýmý azalýrken, üç tabakalý kas yapýsýna sahip olgularýn yüzde daðýlýmýnýn full terme doðru arttýðý belirlendi. Tartýþma: Mesane duvarýnýn kas tabakalarýnda fetal dönemde meydana gelen deðiþikliklerin bilinmesinin farklý patoloji ve anomalilerin tanýmlanmasýna katkýda bulunacaðý düþünülmektedir. Anahtar kelimeler: mesane, fetal geliþim, kas tabakasý, insan fetusu Abstract Objective: The aim of our study is to investigate the development of muscular layers in the wall of urinary bladder during the fetal period. Material and Methods: We performed this study on 130 human fetuses aged between 9-40 weeks of gestation obtained with families. consent from Isparta Maternity and Children.s Hospital between 1997 and 2002. We did the study at the department of anatomy in medicine faculty of Suleyman Demirel University 2004. At first, we removed the bladder from the pelvic cavity. Then, we obtained the specimens from anterior wall of body of bladder. After the routine histological procedure, we embedded the specimens in parraffine. We took serial 5 mm sections from the paraffine blocks and we stained the sections with hematoxylin-eosin. We measured the thickness of total wall, longitudinal and circular muscle layers and evaluated the development of them in the light microscope during the fetal period. Findings: There was no significant difference between sexes for the parameters (p>0.05). All parameters were increasing with gestational age (p<0.001). In the first trimester, 33% of the cases had two layered muscular structure and 67% of the cases had three layered muscle. 86% of the cases in the second trimester and 97% of the cases in the third trimester had three layered muscular structure. All cases had three layers in the full term. Conclusion: Having the knowledge of the changes in smooth muscle of urinary bladder during the fetal period will contribute to define the different pathology and anomalies. Key words: urinary bladder, fetal development, muscular layer, human fetus

References

  • Arýncý K, Elhan A. Anatomi. Güneþ Kitabevi. Ankara. Cilt 1 1997, 400-406.
  • Newman J, Antonakopoulos GN. The fine structure of the human fetal urinary bladder . Development and maturation. A light, transmission and scanning electron microscopic study. J Anat. 1989; 166: 135-150.
  • Matsuno T, Tokunaka S, Koyanagi T. Muscular development in the urinary tract. The J Urol. 1984, 132: 148-152.
  • Wu HY, Baskin LS, Blakey C, Goodman J, Cunha GR. Ultrastructural smooth muscle ontogeny of the rat bladder. Adv Exp Med Biol. 1999;462:93-102.
  • Yang JM, Huang WC. Bladder wall thickness on ultrasonographic cystourethrography. J Ultrasound Med. 2003; 22: 777-782
  • Felix W. The development of the urogenital organs. In: Keibel F and Mall FP, editors. Manual of Human Embryology. Philadelphia, pp: JB Lippincott Co; 1912, p. 752-973.
  • Baker L, Gomez RA. Embryonic development of the ureter and bladder: acquisition of smooth muscle. J Urol. 1998, 160: 545-50.

Year 2009, Volume 16, Issue 1, 16 - 20, 30.03.2009

Abstract

References

  • Arýncý K, Elhan A. Anatomi. Güneþ Kitabevi. Ankara. Cilt 1 1997, 400-406.
  • Newman J, Antonakopoulos GN. The fine structure of the human fetal urinary bladder . Development and maturation. A light, transmission and scanning electron microscopic study. J Anat. 1989; 166: 135-150.
  • Matsuno T, Tokunaka S, Koyanagi T. Muscular development in the urinary tract. The J Urol. 1984, 132: 148-152.
  • Wu HY, Baskin LS, Blakey C, Goodman J, Cunha GR. Ultrastructural smooth muscle ontogeny of the rat bladder. Adv Exp Med Biol. 1999;462:93-102.
  • Yang JM, Huang WC. Bladder wall thickness on ultrasonographic cystourethrography. J Ultrasound Med. 2003; 22: 777-782
  • Felix W. The development of the urogenital organs. In: Keibel F and Mall FP, editors. Manual of Human Embryology. Philadelphia, pp: JB Lippincott Co; 1912, p. 752-973.
  • Baker L, Gomez RA. Embryonic development of the ureter and bladder: acquisition of smooth muscle. J Urol. 1998, 160: 545-50.

Details

Primary Language English
Journal Section Araştırma Makaleleri
Authors

Neslihan Cankara This is me


Gülnur Özgüner This is me


Esra Koyuncu This is me


Kadir Desticioğlu This is me


Osman Sulak This is me

Publication Date March 30, 2009
Submission Date June 1, 2009
Acceptance Date
Published in Issue Year 2009, Volume 16, Issue 1

Cite

Vancouver Cankara N. , Özgüner G. , Koyuncu E. , Desticioğlu K. , Sulak O. The development of muscular layers in the wall of fetal urinary bladder during the fetal period. SDÜ Tıp Fakültesi Dergisi. 2009; 16(1): 16-20.

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