Genital siğili olan kadınlarda servikal HPV ve servikal smear sonuçlarının karşılaştırılması

Year 2020, Volume: 27 Issue: 3, 283 - 287, 01.09.2020

Sercan Serin Ramazan Denizli Önder Sakin Zehra Meltem Pirimoğlu

https://doi.org/10.17343/sdutfd.569556

Abstract

AMAÇ: Genital siğili olan kadınlarda lezyona neden
olan HPV tipini belirlemek ve bu kadınlarda servikal HPV ile sitoloji
örnekleriyle karşılaştırmak

MATERYAL VE METOD: Hastanemize nisan 2014- nisan
2015 tarihleri arasında genital siğil nedeniyle başvuran kadınlardan lezyon
üzerinden ve servikal sürüntüden HPV tiplendirilmesi yapılıp servikal
sitolojileri incelendi. Çalışma prospektif bir çalışma olup hastanemiz etik
kurulundan onay alınmış,  çalışmaya
katılmayı kabul eden kadınlara gerekli bilgilendirme yapılarak aydınlatılmış
rıza belgesi alınmıştır. Çalışmamıza uygun olup rıza veren 44 kadın incelendi.

BULGULAR: Çalışmamız yaşları 17 ile 60 yıl arasında değişmekte olan toplam 44 olgu üzerinde
yapılmıştır. Olguların ortalama yaşları 35.75±11.67 yıldır. Olguların 17’si
(%38.6) 30 yaş altında iken, 27’si (%61.4) 30 yaş ve üzerindedir. Genital
lezyondan alınan örnekte yapılan HPV tiplendirilmesinde 35 (% 79.5) HPV tip
6-11 izlenirken, 3 (%6.8) HPV tip 16-18 tespit edilmiş, 6 (%13,6) olguda ise
HPV tespit edilememiştir. Olguların servikal HPV sonuçları incelendiğinde; 30
(%68.2) HPV tip 6-11 3 (%6.8) HPV tip 16-18 , 2(%4.5) HPV diğer yüksek tip
izlenirken, 9 (% 20.5) olguda servikal HPV negatif tespit edildi. Hastaların
servikal sitolojileri incelendiğinde; 35 (%79.5) smear sonucu normal iken,
5’inde (%11.4) ASCUS, 4’ünde (%9.1) LGSIL tespit edilmiştir.

SONUÇ: Genital siğil
ile başvuran hastalarda servikal HPV ve servikal displazi riskinin artmış
olduğu göz önünde bulundurulmalıdır. Kondillomlu hastalarda servikal muayene
dikkatlice yapılmalı, sitolojik örnekleme alınmalı ve gerektiğinde kolposkopi
eşliğinde biyopsi alınmasını düşünmekteyiz.

Keywords

Siğil, HPV, Smear, Genital Lezyon

Supporting Institution

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Project Number

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Thanks

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Comparison of cervical HPV and smear results in women with genital wart

Abstract

OBJECTIVE: To
determine the type of HPV that causes lesion in women with genital warts and to
compare them with cervical HPV and cytology samples

MATERIAL AND METHODS:
HPV typing and cervical cytology were performed from women who applied to our
hospital between April 2014 and April 2015 due to genital warts. The study was
a prospective study and approval was obtained from the ethics committee of our
hospital and the informed consent was obtained to the women who accepted to
participate in the study. Forty women were given to our study.

RESULTS: Our study was
carried out on 44 patients whose ages ranged from 17 to 60 years. The mean age
of the patients was 35.75 ± 11.67 years. While 17 (38.6%) of the cases were
under 30 years of age, 27 (61.4%) were over 30 years of age. In HPV typing in
genital lesion, 35 (79.5%) HPV type 6-11 were detected, 3 (6.8%) HPV type 16-18
were detected, and 6 (13.6%) could not have HPV. When the cervical HPV results
were examined; 30 (68.2%) HPV type 6-11, 3 (6.8%) HPV type 16-18, 2 (4.5%) HPV
other high type were observed, 9 (20.5%) cases were cervical HPV negative. When
the cervical cytology of the patients were examined; While 35 (79.5%) smear
results were normal, 5 (11.4%) ASCUS and 4 (9.1%) LGSIL were detected.

CONCLUSION: It should
be considered that increased risk of cervical HPV and cervical dysplasia in patients
presenting with genital warts. Cervical examination should be performed
carefully in patients with conduloma, cytological sampling should be taken and
colposcopy-guided biopsy should be taken if necessary.

Keywords

Wart, HPV, Smear, Genital Lesion

Project Number

yok

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