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Çocuklarda COVİD-19 ve Gastrointestinal Sistem

Year 2021, Volume: 28 Issue: COVİD-19 ÖZEL SAYI, 147 - 151, 01.05.2021
https://doi.org/10.17343/sdutfd.904099

Abstract

COVID-19 hastalığı daha iyi tanındıkça ilk tarif edildiğinin aksine hastalık sırasında solunum sistemi dışındaki organ tutulumları ile daha fazla oranda seyrettiği anlaşılmıştır. Gastrointestinal sistem, solunum sistemi dışında en fazla tutulan sistemdir. Bu çalışmada bizim deneyimlerimizi de katarak PubMed veri tabanlı İngilizce yayımlanan makaleler taranarak COVID-19 ilişkili gastrointestinal hastalıklar hakkında bir derleme yapmayı amaçladık.

Supporting Institution

Yok

Project Number

Yok

Thanks

SDÜ Tıp Fakültesi Dergisi Editörleri 26 Mart 2021 Sayın editörler, “Çocuklarda COVID-19 ve Gastrointestinal Sistem” başlıklı derlememizin değerlendirilmesi ve kabulü halinde derginizde yayınlanması için değerli görüşlerinize sunuyoruz. Saygılarımla, Dr Hakan SALMAN

References

  • 1- Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in china, 2019. N Engl J Med. 2020;382:727–33.
  • 2- Lu S, Lin J, Zhang Z, Xiao L, Jiang Z, Chen J, et al. Alert for non-respiratory symptoms of Coronavirus Disease 2019 (COVID-19) patients in epidemic period: A case report of a familial cluster with three asymptomatic COVID-19 patients. J Med Virol. 2021;93(1):518-21.
  • 3- Wang J, Zhao S, Liu M, et al. ACE2 expression by colonic epithelial cells is associated with viral infection, immunity and energy metabolism. Available from: https://www.medrxiv.org/content/10.1101/2020.02.05.20020545v1.full.pdf.
  • 4- Xu Y, Li X, Zhu B et al. Characteristics of pediatric SARS‐CoV‐2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 202;26(4):502-505.
  • 5- Yang Z, Li G, Dai X, Liu G, Li G, Jie Y. Three cases of novel coronavirus pneumonia with viral nucleic acids still positive in stool after throat swab detection turned negative. Chinese Journal of Digestion ; (12): E002-E002, 2020.
  • 6- Puoti MG, Rybak A, Kiparissi F, Gaynor E and Borrelli O. SARS-CoV-2 and the Gastrointestinal Tract in Children. Front Pediatr. 2021 Feb 22;9:617980. doi: 10.3389/fped.2021.617980.
  • 7- Deffner F, Scharr M, Klingenstein S, Klingenstein M, Milazzo A, Scherer S, et al. Histological evidence for the enteric nervous system and the choroid plexus as alternative routes of neuroinvasion by SARS-CoV2. Front Neuroanat. 2020 Oct 6;14:596439. doi: 10.3389/fnana.2020.596439.
  • 8- Ding Y, Yan H, Guo W. Clinical characteristics of children with COVID-19: a meta-analysis. Front Pediatr. 2020 Jul 3;8:431. doi: 10.3389/fped.2020.00431.
  • 9- Xu L, Liu J, Lu M, Yang D, Zheng X. Liver injury during highly pathogenic human coronavirus infections. Liver Int. 2020;40(5):998-1004.
  • 10- Tian Y, Rong L, Nian W, and He Y. Review article: gastrointestinal features in COVID‐19 and the possibility of faecal transmission. Aliment Pharmacol Ther. 2020;51(9): 843–851.
  • 11- Badal S, Bajgain BT, Badal S, Thapa R, Bajgain BB, Santana MJ. Prevalence, clinical characteristics and outcome of pediatric COVID-19: a systematic review and meta-analysis. J Clin Virol. 2021 Feb;135:104715. doi: 10.1016/j.jcv.2020.104715.
  • 12- Zhang C, Shi L, Wang FS. Liver injury in COVID‐19: management and challenges. Lancet Gastroenterol Hepatol. 2020 May;5(5):428-430.
  • 13- Riphagen S, Xabier G, Gonalez-Martinez G, Wilkinson N, Paraskevi T. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395:1607–8.
  • 14- Amisha M; Sturgill, Pharm D, Patricia MM, Yi-Horn, Chika E, Hariprem R. Pediatric COVID-19 and Appendicitis: A Gut Reaction to SARS-CoV-2 ? The Pediatric Infectious Disease Journal. 2021;40(2):49-55. 15- Tullie L, Ford K, Bisharat M, Watson T, Thakkar H, Mullassery D, et al. Gastrointestinal features in children with COVID-19: an observation of varied presentation in eight children. Lancet Child Adolesc Health. 2020;4:19–20.
  • 16- Miller J, Cantor A, Zachariah P, Ahn D, Martinez M and Margolis KG. Gastrointestinal Symptoms as a Major Presentation Component of a Novel Multisystem Inflammatory Syndrome in Children That Is Related to Coronavirus Disease 2019: A Single Center Experience of 44 Cases. Gastroenterology. 2020;159(4):1571–4.
  • 17- Meyer JS, Robinson G, Moonah S, Levin D, McGahren E, Herring K, et al. Acute appendicitis in four children with SARS-CoV-2 infection. J Pediatr Surg Case Rep. 2020. doi: 10.1016/j.epsc.2020.101734.
  • 18- Shahein RA, Young H, Dalabih A. Phlegmonous ileocolitis as a presentation of post SARS-CoV-2 (COVID-19) multisystem inflammatory syndrome in children. Front. Pediatr. 2021, doi.org/10.3389/fped.2021.617980.
  • 19- Martínez-Castaño I, Calabuig-Barbero E, Gonzálvez-Piñera J, Lòpez-Ayala JM. COVID-19 infection is a diagnostic challenge in infants with ileocecal intussusception. Pediatr Emerg Care. 2020;(6):e368. doi: 10.1097/PEC.0000000000002155.
  • 20- Rohani P, Karimi A, Tabatabaie RS, Khalili M, Sayyari A. Protein losing enteropathy and pneumatosis intestinalis in a child with COVID19 infection. J Pediatr Surg Case Rep. 2021 Jan;64:101667. doi: 10.1016/j.epsc.2020.101667.
  • 21- Noda S, Ma J, Romberg EK, Hernandez RE, Ferguson MR. Severe COVID-19 initially presenting as mesenteric adenopathy. Pediatr Radiol. 2021 Jan;51(1):140-143.
  • 22- Jackson RJ, Chavarria HD, and Hacking SM. A Case of Multisystem Inflammatory Syndrome in Children Mimicking Acute Appendicitis in a COVID-19 Pandemic Area. Cureus 2020; 29;12(9) doi:10.7759/cureus.10722.
  • 23- Turner D, Huang Y, Martin-de-Carpi J, Aloi M, Focht G, Kang B, et al. Coronavirus disease 2019 and paediatric inflammatory bowel diseases: global experience and provisional guidance (March 2020) from the paediatric IBD porto group of european society of paediatric gastroenterology, hepatology, and nutrition. JPGN. 2020;70(6):727-733. doi: 10.1097/MPG.0000000000002729.
  • 24- Siddiqui HK, Mehra MR. COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal. J Heart Lung Transplant. 2020;39:405–7.

Pediatric COVID-19 and Gastrointestinal System

Year 2021, Volume: 28 Issue: COVİD-19 ÖZEL SAYI, 147 - 151, 01.05.2021
https://doi.org/10.17343/sdutfd.904099

Abstract

As COVID-19 disease is better known, it has been understood that, contrary to the first description, it presents with organ involvement except the respiratory system during the disease. The gastrointestinal system is the most affected system except the respiratory system. In this study, we aimed to make a review about COVID-19 related gastrointestinal diseases by scanning PubMed-based articles published in English by adding our experience.

Project Number

Yok

References

  • 1- Zhu N, Zhang D, Wang W, Li X, Yang B, Song J, et al. A novel coronavirus from patients with pneumonia in china, 2019. N Engl J Med. 2020;382:727–33.
  • 2- Lu S, Lin J, Zhang Z, Xiao L, Jiang Z, Chen J, et al. Alert for non-respiratory symptoms of Coronavirus Disease 2019 (COVID-19) patients in epidemic period: A case report of a familial cluster with three asymptomatic COVID-19 patients. J Med Virol. 2021;93(1):518-21.
  • 3- Wang J, Zhao S, Liu M, et al. ACE2 expression by colonic epithelial cells is associated with viral infection, immunity and energy metabolism. Available from: https://www.medrxiv.org/content/10.1101/2020.02.05.20020545v1.full.pdf.
  • 4- Xu Y, Li X, Zhu B et al. Characteristics of pediatric SARS‐CoV‐2 infection and potential evidence for persistent fecal viral shedding. Nat Med. 202;26(4):502-505.
  • 5- Yang Z, Li G, Dai X, Liu G, Li G, Jie Y. Three cases of novel coronavirus pneumonia with viral nucleic acids still positive in stool after throat swab detection turned negative. Chinese Journal of Digestion ; (12): E002-E002, 2020.
  • 6- Puoti MG, Rybak A, Kiparissi F, Gaynor E and Borrelli O. SARS-CoV-2 and the Gastrointestinal Tract in Children. Front Pediatr. 2021 Feb 22;9:617980. doi: 10.3389/fped.2021.617980.
  • 7- Deffner F, Scharr M, Klingenstein S, Klingenstein M, Milazzo A, Scherer S, et al. Histological evidence for the enteric nervous system and the choroid plexus as alternative routes of neuroinvasion by SARS-CoV2. Front Neuroanat. 2020 Oct 6;14:596439. doi: 10.3389/fnana.2020.596439.
  • 8- Ding Y, Yan H, Guo W. Clinical characteristics of children with COVID-19: a meta-analysis. Front Pediatr. 2020 Jul 3;8:431. doi: 10.3389/fped.2020.00431.
  • 9- Xu L, Liu J, Lu M, Yang D, Zheng X. Liver injury during highly pathogenic human coronavirus infections. Liver Int. 2020;40(5):998-1004.
  • 10- Tian Y, Rong L, Nian W, and He Y. Review article: gastrointestinal features in COVID‐19 and the possibility of faecal transmission. Aliment Pharmacol Ther. 2020;51(9): 843–851.
  • 11- Badal S, Bajgain BT, Badal S, Thapa R, Bajgain BB, Santana MJ. Prevalence, clinical characteristics and outcome of pediatric COVID-19: a systematic review and meta-analysis. J Clin Virol. 2021 Feb;135:104715. doi: 10.1016/j.jcv.2020.104715.
  • 12- Zhang C, Shi L, Wang FS. Liver injury in COVID‐19: management and challenges. Lancet Gastroenterol Hepatol. 2020 May;5(5):428-430.
  • 13- Riphagen S, Xabier G, Gonalez-Martinez G, Wilkinson N, Paraskevi T. Hyperinflammatory shock in children during COVID-19 pandemic. Lancet. 2020;395:1607–8.
  • 14- Amisha M; Sturgill, Pharm D, Patricia MM, Yi-Horn, Chika E, Hariprem R. Pediatric COVID-19 and Appendicitis: A Gut Reaction to SARS-CoV-2 ? The Pediatric Infectious Disease Journal. 2021;40(2):49-55. 15- Tullie L, Ford K, Bisharat M, Watson T, Thakkar H, Mullassery D, et al. Gastrointestinal features in children with COVID-19: an observation of varied presentation in eight children. Lancet Child Adolesc Health. 2020;4:19–20.
  • 16- Miller J, Cantor A, Zachariah P, Ahn D, Martinez M and Margolis KG. Gastrointestinal Symptoms as a Major Presentation Component of a Novel Multisystem Inflammatory Syndrome in Children That Is Related to Coronavirus Disease 2019: A Single Center Experience of 44 Cases. Gastroenterology. 2020;159(4):1571–4.
  • 17- Meyer JS, Robinson G, Moonah S, Levin D, McGahren E, Herring K, et al. Acute appendicitis in four children with SARS-CoV-2 infection. J Pediatr Surg Case Rep. 2020. doi: 10.1016/j.epsc.2020.101734.
  • 18- Shahein RA, Young H, Dalabih A. Phlegmonous ileocolitis as a presentation of post SARS-CoV-2 (COVID-19) multisystem inflammatory syndrome in children. Front. Pediatr. 2021, doi.org/10.3389/fped.2021.617980.
  • 19- Martínez-Castaño I, Calabuig-Barbero E, Gonzálvez-Piñera J, Lòpez-Ayala JM. COVID-19 infection is a diagnostic challenge in infants with ileocecal intussusception. Pediatr Emerg Care. 2020;(6):e368. doi: 10.1097/PEC.0000000000002155.
  • 20- Rohani P, Karimi A, Tabatabaie RS, Khalili M, Sayyari A. Protein losing enteropathy and pneumatosis intestinalis in a child with COVID19 infection. J Pediatr Surg Case Rep. 2021 Jan;64:101667. doi: 10.1016/j.epsc.2020.101667.
  • 21- Noda S, Ma J, Romberg EK, Hernandez RE, Ferguson MR. Severe COVID-19 initially presenting as mesenteric adenopathy. Pediatr Radiol. 2021 Jan;51(1):140-143.
  • 22- Jackson RJ, Chavarria HD, and Hacking SM. A Case of Multisystem Inflammatory Syndrome in Children Mimicking Acute Appendicitis in a COVID-19 Pandemic Area. Cureus 2020; 29;12(9) doi:10.7759/cureus.10722.
  • 23- Turner D, Huang Y, Martin-de-Carpi J, Aloi M, Focht G, Kang B, et al. Coronavirus disease 2019 and paediatric inflammatory bowel diseases: global experience and provisional guidance (March 2020) from the paediatric IBD porto group of european society of paediatric gastroenterology, hepatology, and nutrition. JPGN. 2020;70(6):727-733. doi: 10.1097/MPG.0000000000002729.
  • 24- Siddiqui HK, Mehra MR. COVID-19 illness in native and immunosuppressed states: a clinical-therapeutic staging proposal. J Heart Lung Transplant. 2020;39:405–7.
There are 23 citations in total.

Details

Primary Language Turkish
Subjects Clinical Sciences
Journal Section Reviews
Authors

Hakan Salman 0000-0002-4973-0122

Mustafa Akçam 0000-0002-4635-7633

Project Number Yok
Publication Date May 1, 2021
Submission Date March 26, 2021
Acceptance Date April 5, 2021
Published in Issue Year 2021 Volume: 28 Issue: COVİD-19 ÖZEL SAYI

Cite

Vancouver Salman H, Akçam M. Çocuklarda COVİD-19 ve Gastrointestinal Sistem. Med J SDU. 2021;28(COVİD-19 ÖZEL SAYI):147-51.

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