B12 VİTAMİN EKSİKLİĞİ OLAN ÇOCUKLARDA HEMATOLOJİK BULGULAR

Year 2022, Volume: 29 Issue: 1, 47 - 51, 01.03.2022

Nergiz Öner , Gülcihan Özek

https://doi.org/10.17343/sdutfd.960640

Abstract

Amaç
Vitamin B12 eksikliği çocukluk çağında sık görülen bir
durumdur ve eksikliğine bağlı olarak çeşitli nörolojik,
hematolojik ve dermatolojik bulgular görülebilmektedir.
Çalışmanın amacı B12 vitamini eksikliği tanısı
alan çocuklarda hematolojik bulguları değerlendirmektir.
Gereç ve Yöntem
Çocuk Hematoloji Bölümü'nde B12 eksikliği tanısı ile
izlenen hastaların hematolojik verileri geriye dönük
olarak incelendi.
Bulgular
Çalışmamızda yüz yirmi dört hastanın hematolojik verileri
değerlendirildi. Kırksekiz hastada anemi, 8 hastada
trombositopeni ve 6 hastada lökopeni tespit edildi.
İki süt çocuğu uzamış sarılık ve hemolitik anemi ile
başvurdu. Hastaların ortalama vitamin B12 düzeyleri
97.3±30.6 (5-140) pg/ml idi.
Sonuç
Vitamin B12 eksikliği gelişmekte olan ülkelerde sık
görülen bir hastalıktır ve çoğunlukla annedeki eksiklikten
kaynaklanır. Çalışmamızda 52 bebekten 42'sinin
(%80) annesinde B12 vitamini eksikliği saptandı.
Buda gebelerde B12 vitamini düzeyinin belirlenmesinin
ve eksiklik durumunda tedavisinin önemini açıkça
göstermektedir. B12 vitamini eksikliği olan hastalar
çeşitli nedenlerle hastaneye başvurabilirler. Bu nedenle
özellikle uzamış sarılık ve hemolitik anemi ile
başvuran hastalarda B12 vitamini eksikliğinin neden
olabileceği akılda tutulmalıdır.

Keywords

Vitamin B12 eksikliği, hematolojik bulgular, çocuklar

HEMATOLOGICAL FINDINGS IN CHILDREN WITH VITAMIN B12 DEFICIENCY

Abstract

Objective
Vitamin B12 deficiency is a common condition in
childhood and various neurological, hematological,
and dermatological findings could be seen due to its
deficiency. The aim of the study is to evaluate the
hematological findings in children diagnosed with
vitamin B12 deficiency.
Materials and Methods
Hematological data of children with B12 deficiency
who were examined in Pediatric Hematology
Department were retrospectively reviewed.
Results
Hematological data of one hundred twenty-four
patients were assessed in our study. Anemia,
thrombocytopenia and leucopenia were detected in
48 patients, 8 patients and 6 patients, respectively.
Two infants presented with prolonged jaundice and
hemolytic anemia. The mean vitamin B12 levels of the
patients were 97.3±30.6 (5-140) pg/ml.
Conclusion
Vitamin B12 deficiency is a common disease in
developing countries and it is mostly of maternal
origin. In our study, vitamin B12 deficiency in mothers
of 42 out of 52 infants (80%) were discovered. This
percentage clearly shows the importance of the vitamin
B12 level determination in pregnant women and its
treatment in case of deficiency. Patients with vitamin
B12 deficiency might be admitted to the hospital for
various reasons. Therefore, it is recommended to
keep in mind that vitamin B12 deficiency might be
the base of various diseases, especially for patients
presenting prolonged jaundice and hemolytic anemia.

Keywords

Vitamin B12deficiency, hematological findings, children

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