Subkutanöz konnektif dokuda çeşitli self adeziv rezin simanların biyouyumluluklarının değerlendirilmesi: In vivo çalışma

Year 2023, , 429 - 433, 21.08.2023

Anıl Gerçek , Bilge Turhan Bal , Emre Barış

https://doi.org/10.15311/selcukdentj.1185537

Abstract

Amaç: Bu calışmanın amacı üç farklı self adeziv rezin simana karşı gelişen subkutanöz doku reaksiyonunu incelemektir.
Gereç ve Yöntemler: 63 adet polietilen tüp içine üç farklı self adeziv rezin siman yerleştirildi. ((Grup Z [Zirconite], Grup P [Panavia SA], and Grup H [High Q Bond]). 21 polietilen tüp boş bırakıldı ve kontrol grubu olarak kullanıldı (Grup C). Bütün tüpler 21 adet farenin subkutanöz dokusuna yerleştirildi. Her siman tipinden subkutan olarak yerleştirilmiş siman örnekleri, 7, 30, 90. günlerde çıkartıldı. İnflamatuar hücrelerinin sayısal değerlendirmesi her örneğin 5 farklı alanından yapıldı.
Bulgular: 2 fare dışında tüm hayvanlar takip periyodları boyunca canlı kaldı. 90. günde Grup C, H, P ve Z de enflamatuar hücrelerin ortalama değerleri sırasıyla 14 (±1.8), 15.1 (±3.5), 96 (±12.1), 16 (±2.1) şeklindedir. Panavya dışında tüm gruplarda fibröz kapsül kalınlığı zaman içinde anlamlı derecede azalmıştır.
Sonuç: Self adesiv rezin simanların biyouyumluluğu materyale bağlı olarak farklılık göstermektedir. 90. Günde High Q Bond ve Zirconite yeterli biyouyumluluk değeri gösterirken Panavya siman da orta derecede inflamatuar cevap gözlemlenmiştir.

Keywords

Biyouyumlu materyaller, enflamasyon, rezin simanlar

Evaluation of the biocompatibility of various self-adhesive resin cements on subcutaneous connective tissue: An in vivo study

Abstract

Background: The purpose of the study was to examine the subcutaneous connective tissue reaction to three self-adhesive resin cements.
Methods: Sixty-three polyethylene tubes were filled with three different self-adhesive resin cements (Group Z [Zirconite], Group P [Panavia SA], and Group H [High Q Bond]). Twenty-one polyethylene tubes remained empty and were used as controls (Group C). All tubes were implanted into the subcutaneous tissue of the 21 rats. Specimens from each cement type were obtained at 7, 30, and 90 days. Quantitative assessments of inflammatory cells were performed in 5 different areas of each specimen.
Results: All animals survive during the follow-up periods except two rats. The mean values of inflammatory cells at 90 days were 14 (±1.8), 15.1 (±3.5), 96 (±12.1), 16 (±2.1) in Groups C, H, P, and Z, respectively. The thicknesses of the fibrous capsule decreased significantly with time in all groups except Group P.
Conclusion: Biocompatibility of self-adhesive resin cements was material-dependent. High Q Bond and Zirconite exhibited satisfactory biocompatibility; however, Panavia demonstrated a moderate inflammatory response at 90 days.

Keywords

biocompatible materials, inflammation, resin cements

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