Prevalence of Mandibular Second Premolar Agenesis in Individuals and Associated Factors: A Meta-Analysis

Year 2022, , 182 - 190, 27.04.2022

Nilüfer Üstün , Can Özükoç

https://doi.org/10.15311/selcukdentj.939183

Abstract

Background: The purposes of this study were to determine the prevalence and patterns of mandibular second premolar agenesis in individuals by meta-analysis methodology.
Methods: Two investigators conducted a literature search independently by inclusion criteria to reveal articles on mandibular second premolar agenesis. PubMed, Google Scholar, Ovid Medline, Web of Science Core Collection databases were scanned and a total of 3,988 studies were initially extracted from all databases, then 12 articles were selected which met inclusion and exclusion criteria for the meta-analysis.
Results: The estimated overall prevalence of mandibular second premolar in individuals was 3.26 %. No statistically significant difference was found in the prevalence of mandibular second premolar agenesis by gender [95 % Cl: 1.18 (0.96, 1.45); p>0.05]. Males were found to have a significantly higher prevalence of unilateral mandibular second premolar agenesis than females (combined OR 0.69; 95 % CI: 0.38-1.25; p<0.05). However, females had a significantly higher prevalence of bilateral mandibular second premolar agenesis than males (combined OR 1.57; 95 % Cl: 0.91-2.72; p<0.05). No difference was found in the prevalence of mandibular second premolar agenesis between the right and left mandibular region [95 % Cl: 1.04 (0.91-1.20); p>0.05].
Conclusion: This study supports some previous findings regarding mandibular second premolar agenesis and presents new observations on gender differences, inter-maxillary patterns of mandibular second premolar agenesis in the mandible—including unilateral and/or bilateral occurrence and jaw site.

Keywords

Mandibular Second Premolar, Agenesis, Hypodontia

Bireylerde mandibular ikinci premolar eksikliğinin prevalansı ve ilişkili faktörler: meta-analiz çalışması

Abstract

Amaç: Bu çalışmada, bireylerde görülen mandibular ikinci premolar agenezisi prevalansının ve ilişkili faktörlerin meta-analiz yöntemi ile değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntemler: Dahil edilme kriterlerinden bağımsız olarak, mandibular ikinci premolar agenezisi ile ilgili çalışmalar iki farklı araştırmacı tarafından tarandı. PubMed, Google Scholar, Ovid Medline, Web of Science Core Collection veritabanları kullanılarak yapılan başlangıç taraması sonucunda 3.988 çalışma belirlendi. Bu çalışmalardan değerlendirilmek üzere, meta-analiz yönteminin uygulanabilmesi için gerekli kriterleri sağlayan toplam 12 çalışma seçildi.
Bulgular: Bireylerdeki mandibular ikinci premolar agenezisi prevalansının % 3.26 oranında olduğu görüldü; ancak prevalans oranları cinsiyete göre değerlendirildiğinde kadınlar ve erkekler arasında istatistiksel açıdan anlamlı bir farklılık saptanmadı [% 95 Cl: 1.18 (0.96, 1.45); p>0.05]. Erkeklerin kadınlara kıyasla anlamlı derecede daha yüksek oranda unilateral mandibular ikinci premolar agenezisi prevalansına sahip olduğu görüldü (ortak OD 0.69; % 95 CI: 0.38-1.25; p<0.05). Bununla birlikte, mandibular ikinci premoların bilateral agenezisinin kadınlarda erkeklere göre anlamlı derecede daha yüksek oranda olduğu görüldü (ortak OD 1.57; % 95 Cl: 0.91-2.72; p<0.05). Mandibular ikinci premolar agenezisi, sağ veya sol mandibular bölgede görülme sıklığına göre değerlendirildiğinde ise istatistiksel olarak anlamlı bir farklılık bulunmadı [% 95 Cl: 1.04 (0.91-1.20); p>0.05].
Sonuç: Hastalara daha kapsamlı tedavi planı sağlamak ve daha olumlu tedavi sonuçları elde etmek için mandibular ikinci premolar diş eksikliğinin doğru ve erken teşhisi önem taşımaktadır.

Keywords

mandibular ikinci premolar, agenezis, hipodonti, prevalans, konjenital eksik diş

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