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Hidroksiklorokin Sülfat Kaynaklı Plazma Hücreli Gingivitis: Olgu Sunumu

Year 2020, Volume: 7 Issue: 2, 347 - 353, 01.08.2020
https://doi.org/10.15311/selcukdentj.567866

Abstract

Plazma
hücreli gingivitis, dişeti bağ dokusunda yoğun plazma hücresi infiltrasyonu, klinik
olarak sınırları belirgin eritematöz, ödematöz dişeti ile karakterize olan dişetinin
etiyolojisi tam bilinmeyen nadir görülen benign bir durumudur. Dişeti kızarık,
yumuşak bazen granüler görünür ve kolay kanar. Plazma hücreli gingivitisin
allerjik menşeyli olduğu düşünülmektedir ve muhtemelen sakız, dişmacunu ya da
çeşitli gıdalardaki bileşenlerle ilişkili olabilir. Maruz kalınan allerjenin
kesilmesi ile lezyon iyileşmektedir.
Bu olgu sunumunda, 62
yaşındaki bayan hasta dişetlerinde kanama ve kızarıklık nedeni ile kliniğimize başvurdu.

Faz
I periodontal tedaviden 1 hafta sonra dişetlerinde bariz eritem mevcuttu.
Alınan biyopsi örneklerinin histopatolojik analizi sonucu plazma hücreli
gingivitis teşhisi kondu. Allerjen olarak plazma hücreli gingivitise neden olan
hidroksiklorokin isimli antiromatizmal ilacın kesilmesi sonucu dişetlerinde tam
iyileşme gözlendi.

References

  • 1. Anil S. Plasma cell gingivitis among herbal toothpaste users: a report of three cases. J Contemp Dent Pract 2007;8:60-66.
  • 2. Patanwala A, Fisher, E.W. ,Chapple, L.L.C. Plasma Cell Gingivitis Affecting the Gingiva, Palatal Mucosa and Laryngael Cords. Perio 2006;3:123-128.
  • 3. Poswillo D. Plasmacytosis of the gingiva. Br J Oral Surg 1968;5:194-202.
  • 4. Ababneh KT. Biopsied gingival lesions in northern Jordanians: A retrospective analysis over 10 years. Int J Periodontics Restorative Dent 2006;26:387-393.
  • 5. Gargiulo AV, Ladone JA, Ladone PA, Toto PD. Case report: plasma cell gingivitis A. CDS Rev 1995;88:22-23.
  • 6. Lamey PJ, Lewis MA, Rees TD, Fowler C, Binnie WH, Forsyth A. Sensitivity reaction to the cinnamonaldehyde component of toothpaste. Br Dent J 1990;168:115-118.
  • 7. Macleod RI, Ellis JE. Plasma cell gingivitis related to the use of herbal toothpaste. Br Dent J 1989;166:375-376.
  • 8. Serio FG, Siegel MA, Slade BE. Plasma cell gingivitis of unusual origin. A case report. J Periodontol 1991;62:390-393.
  • 9. Marker P, Krogdahl A. Plasma cell gingivitis apparently related to the use of khat: report of a case. Br Dent J 2002;192:311-313.
  • 10. Lamdari N, Pradhan S. Plasma cell gingivitis: a case report. JNMA J Nepal Med Assoc 2012;52:85-87.
  • 11. Hedin CA, Karpe B, Larsson A. Plasma-cell gingivitis in children and adults. A clinical and histological description. Swed Dent J 1994;18:117-124.
  • 12. Sollecito TP, Greenberg MS. Plasma cell gingivitis. Report of two cases. Oral Surg Oral Med Oral Pathol 1992;73:690-693.
  • 13. Palmer RM, Eveson JW. Plasma-cell gingivitis. Oral Surg Oral Med Oral Pathol 1981;51:187-189.
  • 14. Keskin ED, Seçkin, Ü., Bodur, H., Özcan, M., İkincioğulları, A. Ototoxicity due to antimalarial therapy in patients with rheumatoid arthritis: Two case reports. . Turkish Journal of Physical Medicine and Rehabilitation 2008;54 (1):27-29.
  • 15. Melikoglu MA, Melikoglu M, Gurbuz U, Budak BS, Kacar C. Hydroxychloroquine-induced hyperpigmentation: a case report. J Clin Pharm Ther 2008;33:699-701.

Hydroxychloroquine Sulphate-Induced Plasma Cell Gingivitis: Case report

Year 2020, Volume: 7 Issue: 2, 347 - 353, 01.08.2020
https://doi.org/10.15311/selcukdentj.567866

Abstract

Plasma
cell gingivitis is a rare benign condition of the gingiva of unknown exact etiology
characterized by demarcated erythematous and edematous gingiva clinically and a
heavy plasma cell infiltration into the gingival connective tissue.
The
gingiva appears red, friable, and sometimes granular and bleeds easily. Plasma
cell gingivitis is thought to be allergic in origin, possibly related to
components of chewing gum, dentifrices, or various diet components. Cessation
of exposure to the allergen brings resolution of the lesion. In this case
report, 62 years old female patient referred to our clinic because of gingival bleeding
and erythema. Apparent erythema was still seen in gingiva 1 week after Phase I
periodontal treatment. Plasma cell gingivitis was diagnosed after
histopathologic analysis of biopsied tissues. Complete gingival healing was observed
after cessation of anti-rheumatic drug named hydroxychloroquine as an allergen
causing plasma cell gingivitis.

References

  • 1. Anil S. Plasma cell gingivitis among herbal toothpaste users: a report of three cases. J Contemp Dent Pract 2007;8:60-66.
  • 2. Patanwala A, Fisher, E.W. ,Chapple, L.L.C. Plasma Cell Gingivitis Affecting the Gingiva, Palatal Mucosa and Laryngael Cords. Perio 2006;3:123-128.
  • 3. Poswillo D. Plasmacytosis of the gingiva. Br J Oral Surg 1968;5:194-202.
  • 4. Ababneh KT. Biopsied gingival lesions in northern Jordanians: A retrospective analysis over 10 years. Int J Periodontics Restorative Dent 2006;26:387-393.
  • 5. Gargiulo AV, Ladone JA, Ladone PA, Toto PD. Case report: plasma cell gingivitis A. CDS Rev 1995;88:22-23.
  • 6. Lamey PJ, Lewis MA, Rees TD, Fowler C, Binnie WH, Forsyth A. Sensitivity reaction to the cinnamonaldehyde component of toothpaste. Br Dent J 1990;168:115-118.
  • 7. Macleod RI, Ellis JE. Plasma cell gingivitis related to the use of herbal toothpaste. Br Dent J 1989;166:375-376.
  • 8. Serio FG, Siegel MA, Slade BE. Plasma cell gingivitis of unusual origin. A case report. J Periodontol 1991;62:390-393.
  • 9. Marker P, Krogdahl A. Plasma cell gingivitis apparently related to the use of khat: report of a case. Br Dent J 2002;192:311-313.
  • 10. Lamdari N, Pradhan S. Plasma cell gingivitis: a case report. JNMA J Nepal Med Assoc 2012;52:85-87.
  • 11. Hedin CA, Karpe B, Larsson A. Plasma-cell gingivitis in children and adults. A clinical and histological description. Swed Dent J 1994;18:117-124.
  • 12. Sollecito TP, Greenberg MS. Plasma cell gingivitis. Report of two cases. Oral Surg Oral Med Oral Pathol 1992;73:690-693.
  • 13. Palmer RM, Eveson JW. Plasma-cell gingivitis. Oral Surg Oral Med Oral Pathol 1981;51:187-189.
  • 14. Keskin ED, Seçkin, Ü., Bodur, H., Özcan, M., İkincioğulları, A. Ototoxicity due to antimalarial therapy in patients with rheumatoid arthritis: Two case reports. . Turkish Journal of Physical Medicine and Rehabilitation 2008;54 (1):27-29.
  • 15. Melikoglu MA, Melikoglu M, Gurbuz U, Budak BS, Kacar C. Hydroxychloroquine-induced hyperpigmentation: a case report. J Clin Pharm Ther 2008;33:699-701.
There are 15 citations in total.

Details

Primary Language Turkish
Subjects Dentistry
Journal Section Case Report
Authors

Mehmet Sağlam

Türkel Hasanzade This is me

Publication Date August 1, 2020
Submission Date May 20, 2019
Published in Issue Year 2020 Volume: 7 Issue: 2

Cite

Vancouver Sağlam M, Hasanzade T. Hidroksiklorokin Sülfat Kaynaklı Plazma Hücreli Gingivitis: Olgu Sunumu. Selcuk Dent J. 2020;7(2):347-53.