Hidroksiklorokin Sülfat Kaynaklı Plazma Hücreli Gingivitis: Olgu Sunumu

Year 2020, Volume: 7 Issue: 2, 347 - 353, 01.08.2020

Mehmet Sağlam , Türkel Hasanzade

https://doi.org/10.15311/selcukdentj.567866

Abstract

Plazma
hücreli gingivitis, dişeti bağ dokusunda yoğun plazma hücresi infiltrasyonu, klinik
olarak sınırları belirgin eritematöz, ödematöz dişeti ile karakterize olan dişetinin
etiyolojisi tam bilinmeyen nadir görülen benign bir durumudur. Dişeti kızarık,
yumuşak bazen granüler görünür ve kolay kanar. Plazma hücreli gingivitisin
allerjik menşeyli olduğu düşünülmektedir ve muhtemelen sakız, dişmacunu ya da
çeşitli gıdalardaki bileşenlerle ilişkili olabilir. Maruz kalınan allerjenin
kesilmesi ile lezyon iyileşmektedir. Bu olgu sunumunda, 62
yaşındaki bayan hasta dişetlerinde kanama ve kızarıklık nedeni ile kliniğimize başvurdu.
Faz
I periodontal tedaviden 1 hafta sonra dişetlerinde bariz eritem mevcuttu.
Alınan biyopsi örneklerinin histopatolojik analizi sonucu plazma hücreli
gingivitis teşhisi kondu. Allerjen olarak plazma hücreli gingivitise neden olan
hidroksiklorokin isimli antiromatizmal ilacın kesilmesi sonucu dişetlerinde tam
iyileşme gözlendi.

Keywords

Gingivitis, hidroksiklorokin, hipersensivite

Hydroxychloroquine Sulphate-Induced Plasma Cell Gingivitis: Case report

Abstract

Plasma
cell gingivitis is a rare benign condition of the gingiva of unknown exact etiology
characterized by demarcated erythematous and edematous gingiva clinically and a
heavy plasma cell infiltration into the gingival connective tissue. The
gingiva appears red, friable, and sometimes granular and bleeds easily. Plasma
cell gingivitis is thought to be allergic in origin, possibly related to
components of chewing gum, dentifrices, or various diet components. Cessation
of exposure to the allergen brings resolution of the lesion. In this case
report, 62 years old female patient referred to our clinic because of gingival bleeding
and erythema. Apparent erythema was still seen in gingiva 1 week after Phase I
periodontal treatment. Plasma cell gingivitis was diagnosed after
histopathologic analysis of biopsied tissues. Complete gingival healing was observed
after cessation of anti-rheumatic drug named hydroxychloroquine as an allergen
causing plasma cell gingivitis.

Keywords

Gingivitis, hydroxychloroquine, hypersensitivity

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