Review
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ÇOCUK DİŞ HEKİMLİĞİNDE GÜMÜŞ DİAMİN FLORÜR KULLANIMI

Year 2022, Volume: 9 Issue: 2, 652 - 661, 24.08.2022
https://doi.org/10.15311/selcukdentj.980001

Abstract

Öz:
Gümüş diamin florür (GDF); diamin gümüş iyonu ve florür iyonundan oluşan renksiz ve topikal olarak uygulanabilen alkalen bir çözeltidir. Gümüş iyonlarının antibakteriyel özelliği ile florun çürük önleyici etkileri birleştirilerek Japonya’da 1969’ların sonunda GDF geliştirilmiştir. 2014 yılında ise Amerikan Gıda ve İlaç Dairesi (U.S Food and Drug Administration, FDA) tarafından diş hassasiyeti tedavisi için onaylanmıştır. Ancak son zamanlarda anti-karyojenik özellikleri ve dental plak biyofilminin büyümesini inhibe etmesi nedeniyle çürük kontrolünde kullanılmaktadır.
GDF içerisindeki gümüş (Ag) iyonları, Streptokok mutans’ın büyümesini inhibe etmekte ve dental plaktaki S.mutans’ın metabolik aktivitesini azaltmaktadır. GDF içerisindeki flor iyonları ise çürüğün ilerlemesini önlemektedir. Gümüş ve florun sinerjistik etkileri ile çürük sürecinin durdurulabileceği ve yeni lezyon gelişiminin önlenebileceği ileri sürülmüştür. Amerikan Pediatrik Diş Hekimleri Birliği; özel sağlık bakım ihtiyacı olan çocuklar da dahil olmak üzere çocuk ve ergenlerde çürük yönetimi için GDF kullanımını tavsiye etmektedir.Bu derlemenin amacı; gümüş diamin florürün özellikle çürük riski yüksek çocuklarda ve tedavi imkanının kısıtlı olduğu durumlarda restoratif materyallere alternatif olarak daha yaygın olarak kullanılmasını sağlamaktır.
Abstract:
Silver diamine fluoride is a colorless and topically applicable alkaline solution consisting of diamine silver ion and fluoride ion. SDF was developed in Japan in the late 1969 by combining the antibacterial properties of silver ions with the caries preventive effects of fluorine ions. In 2014, it was approved by the US Food and Drug Administration (U.S. Food and Drug Administration, FDA) for the treatment of tooth sensitivity. However, it has recently been used in the control of dental caries due to its anti-cariogenic properties and inhibition of dental plaque biofilm growth. Silver (Ag) ions in SDF inhibit the growth of Streptococcus mutans and reduce the metabolic activity of S.mutans in dental plaque. Fluorine ions in SDF prevent the progression of caries.
It has been suggested that the caries process can be stopped and new caries lesion development can be prevented with the synergistic effects of silver and fluorine. The American Association of Pediatric Dentists recommends the use of SDF for caries management in children and adolescents, including children with special health care needs. The aim of this review is to ensure that silver diamine fluoride solution is used more widely as an alternative to restorative materials, especially in children with high caries risk and in cases where treatment possibilities are limited.

Supporting Institution

yoktur.

Project Number

yoktur.

References

  • KAYNAKÇA Akyildiz, M., & Saroglu Sönmez, I. (2019). comparison of remineralising potential nano silver fluoride, silver diamine fluoride and sodıum fluoride varnish on artifical caries an in viro study. Oral Health Prev Dent, 469-77.
  • Cernigliaro, D., Kumar, A., & Northridge, M. (2019). Caregiver satisfaction with interim silver diamine fluoride applications for their children with caries prior to operating room treatment or sedation. J Public Health Dent ., 286-91.
  • Crystal , Y., & Marghalani , A. (2017). Use of Silver Diamine Fluoride for Dental Caries Management in Children and Adolescents, Including Those with Special Health Care Needs. Pediatr Dent, 135-45.
  • Duangthip , D., Fung , M., Wong , M., Chu , C., & Lo , E. (2017). Adverse Effects of Silver Diamine Fluoride Treatment among Preschool Children. J Dent Res, 395-401.
  • Duker , M., Hayashi, J., Chan , D., Tagami , J., & Sadr, A. (2019). Effect of silver diamine fluoride and potassium iodide on bonding to demineralized dentin. Am J Dent, 32(3), 143-46.
  • Espíndola-Castro, L., Rosenblatt, A., Galembeck, A., & Monteiro, G. (2020). Dentin Staining Caused by Nano-silver Fluoride: A Comparative Study. Oper Dent, 45(4), 435-441.
  • Huebner , C., Milgrom, P., & Cunha-Cruz, J. (2020). Parents' Satisfaction with Silver Diamine Fluoride Treatment of Carious Lesions in Children. J Dent Child, 4-11.
  • Jabin , Z., Vishnupriya, V., & Agarwal, N. (2020). Effect of 38% silver diamine fluoride on control of dental caries in primary dentition: A Systematic review. J Family Med Prim Care, 1302-1307.
  • Jiang , M., Mei , M., Wong , M., Chu , C., & Lo, E. (2020). Effect of silver diamine fluoride solution application on the bond strength of dentine to adhesives and to glass ionomer cements: a systematic review. BMC Oral Health, 20(1).
  • Kucukyilmaz , E., Savas , S., Akcay , M., & Bolukbasi, B. (2016). Effect of silver diamine fluoride and ammonium hexafluorosilicate applications with and without Er:YAG laser irradiation on the microtensile bond strength in sound and caries-affected dentin. Lasers Surg Med, 62-69.
  • Li , Y., Liu, Y., Psoter , W., Nguyen, O., & Bromage , T. (2019). Assessment of the Silver Penetration and Distribution in Carious Lesions of Deciduous Teeth Treated with Silver Diamine Fluoride. Caries Res, 431-440.
  • Luk , K., Niu, J., & Gutknecht, N. (2021). Preventing Enamel Caries Using Carbon Dioxide Laser and Silver Diamine Fluoride. Photobiomodul Photomed Laser Surg.
  • Luk , K., Zhao, I., & Yu , O. (2020). Caries Prevention Effects of Silver Diamine Fluoride with 10,600 nm Carbon Dioxide Laser Irradiation on Dentin. Photobiomodul Photomed Laser Surg, 295-300.
  • Mei , M., Yan , Z., Duangthip , D., Niu , J., & Yu, O. (2020). Effect of silver diamine fluoride on plaque microbiome in children. J. Dent.
  • Quock , R., Barros, J., Yang, S., & Patel, S. (2012). Effect of silver diamine fluoride on microtensile bond strength to dentin. Oper Dent, 37(6), 610-6.
  • Romão, D., Fernández, C., & Santos, L. (2020). Commercial Silver Diamine Fluoride (SDF) Products on Caries Lesion Progression in Primary Enamel: An In Vitro Study. Oral Health Prev Dent, 1025-1029.
  • Timms, L., Sumner, O., Deery , C., & Rogers, H. (2020). Everyone else is using it, so why isn't the UK? Silver diamine fluoride for children and young people. Community Dent Health, 143-49.
  • Turton, B., Horn , R., & Durward , C. (2020). Caries arrest and lesion appearance using two different silver fluoride therapies on primary teeth with and without potassium iodide: 12-month results. Clin Exp Dent Res, 28, 1-11.
  • Yua, O., Mei, M., & Zhao, I. (2018). Remineralisation of enamel with silver diamine fluoride and sodium fluoride. 344-52.
  • Zhao , I., Yin , I., Mei , M., & Lo, E. (2020). Remineralising Dentine Caries Using Sodium Fluoride with Silver Nanoparticles: An In Vitro Study. Filters applied: 1 year. Clear all, 2829-2839.
  • Zhao , I., Chu, S., Yu, O., Mei , M., Chu , C., & Lo , E. (2019). Effect of silver diamine fluoride and potassium iodide on shear bond strength of glass ionomer cements to caries-affected dentine. Int Dent J, 69(5), 341-347.
  • Agob , J., Aref , N., & Al-Wakeel , E. (2018). Effect of casein phosphopeptide-amorphous calcium phosphate on fluoride release and micro-shear bond strength of resin-modified glass ionomer cement in caries-affected dentin.,». Restor Dent Endod, 43(4).
  • Aksrapak, P. (2018). Microtensile Bond Strength Between Glass Ionomer Cement and Silver Diamine Fluoride-Treated Carious Primary Dentin. Pediatric dentistry, 40(4), 291-295.
  • Bahar, A., & Tagomori, S. (1994). The Effect of normal pulsed Nd-YAG laser irradiation on pits and fissures in humman teeth. Caries Research Journal, 28, 460-467.
  • Bau MEYER, J. C. (2018, November 12). Play it SMART:silver diamine fluorideplus ITR for dental caries. http://www.dentistryiq.com adresinden alındı
  • Bimstein, E., & Damm, D. (2018). Human Primary Tooth Histology Six Months after Treatment with Silver Diamine Fluoride. The Journal of Clinical Pediatric Dentistry, 42(6), 442-444.
  • Chaussain-Miller, C., Fioretti, F., Goldberg, M., & Menashi, M. (2006). The Role of matrix metalloproteinases in human caries. Journal of Dental Researh, 85(1), 22-32.
  • Chu, C., & Lo, E. (2008). Microhardness of dentine in primary teeth after topical fluoride applications. Journal of Dentistry, 36(6), 387-91.
  • Chu, c., & Lo, E. (2008). Promoting Caries Arrest in Children with Silver Diamine Fluoride. Oral Health Preventive Dentistry, 6(4), 315-321.
  • Craig, G., Knight, G., & Melntyre, J. (2012). Clinical evaluation of diamine silver fluoride/potassium iodide as a dentine desensitizing agent. A pilot study. Australian DentalJournal, 57(3), 308-11.
  • Crystal, Y., & Niderrman, R. (2019). Evidence-Based Dentistry Update on Silver Diamine Fluoride. Dental the Clinics North America, 63(1), 45-68.
  • Crystal, Y., Janal, M., Hamilton, D., & Niederman, R. (2017). Parental perceptions and acceptance of silver diamine fluoride staining. Journal of the American Dental Association, 148(7), 510-518.
  • DenBesten, P., & Li, W. (2011). chronic fluoride toxicity dental fluorosis. Monographs in Science(22), 81-96.
  • Duangthip, D., Fung, M., Wong, M., Chu, C., & Lo, E. (2018). Adverse Effects of Silver Diamine Fluoride Treatment among Preschool Children. Journal of dental research, 97(4), 395-401.
  • Fancher, M., Fournier, S., Townsend, J., & Lallier, T. (2019). Cytotoxic effects of silver diamine fluoride. Journal of American Dentistry, 32(3), 152-156.
  • Firouzmandi, M., Shafiei, F., Jowkar, Z., & Nazemi, F. (2019). Effect of Silver Diamine Fluoride and Proanthocyanidin on Mechanical Properties of Caries-Affected Dentin. European Journal of Dentistry, 13(2), 255-60.
  • Fung, M., Duangthip, D., Wong, M., Lo, E., & Chu, C. (2016). Arresting dentine caries with different concentra-tion and periodicity of silver diamine fluoride. Clin Trans Res, 143-52.
  • Gao, S., Zhao, I., & Hiraishi, N. (2016). Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children:A Systematic Review. International & American Associations for Dental Research 2016, 1(3), 201-10.
  • Gao, S., Zhao, I., Hirashi, N., Duangthip, D., Mei, M., Lo, E., & Chu, C. (2016). Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children: A Systematic Review. Journal of Dental Research, 1(3), 201-10.
  • Gotjamanos, T. (1997). Safety İssues Related to the use of silver fluoride in pediatric dentistry. Australia Dental Journal, 42(3), 166-8.
  • Horst, J., Tanzer, J., & Milgrom, P. (2019). fluorides and other preventive strategies for tooth decay. dent clin north am., 62(2), 207-34.
  • Hosoya , Y., Aritomi, K., & Goto, G. (1990). Pulpal response to diammine silver fluoride. (2). Application on exposed pulps]. Shoni Shikagaku Zasshi, 327-37.
  • Hu, S., Meyer, B., & Duggal, M. (2018). A silver renaissance dentistry. European Archives of Paediatric Dentistry, 19(4), 221-227.
  • Kawasaki, A., Suge, T., Ishikawa, K., & Ozaki, K. (2005). Ammonium hexafluorosilicate increased acid resistance of bovine enamel and dentine. JOURNAL OF MATERIALS SCIENCE:, 16(5), 461-466.
  • Knight, G., Mclntyre, J., & Craig, G. (2009). Inability to form a biofilm of Streptococcus mutans on silver fluoride- and potassium iodide-treated demineralized dentin. Quintessence İnternational, 40(2), 155-161.
  • Korwar, A., Sharma, S., & Naseem, S. (2015). Pulp Response to high Fluoride releasing glass ionomer silver diamine fluoride and calcium hydroxide usedfor indrect pulp treatment:an in-vivo comparative study. Contemp Clin Dent, 6(3), 288-92.
  • Law, A., & Messer, H. (2004). An evidence-based analysis of the antibacterial effectiveness of intracanal medicaments. Journal of Endodontics, 10(689-94), 30.
  • Li, R., Lo, E., Liu, B., Wong, M., & Chu, C. (2015). Randomized clinical trial on arresting dental root caries through silver diammine fluoride applications in community-dwelling elders. Journal of Dental Research Meeting Abstracts(51), 15-20.
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  • Yu, O., Zhao, I., Mei, M., & .Lo, E. (2018). Caries-arresting effects of silver diamine fluoride and sodium fluoride on dentine caries lesions. Journal of Dentistry, 65-71.
  • Zhao, I., Gao, S., & Duangthip, D. (2018). Mechanisms of silver diamine fluoride on arresting caries: a literature review. İnternational Dental Journal, 68(2), 67-76.
  • Zhao, I., Mei, M., Burrow, M., Lo, E., & Chu, C. (2017). Effect of Silver Diamine Fluoride and Potassium Iodide Treatment on Secondary Caries Prevention and Tooth Discolouration in Cervical Glass Ionomer Cement Restoration. İnternational Journal of Molecular Sciences, 18(2), 340-54.
  • Zhao, I., Mei, M., Burrow, M., Lo, E., & Chu, C. (2017). Prevention of secondary caries using silver diamine fluoride treatment and casein phosphopeptide-amorphous calcium phosphate modified glass-ionomer cement. Journal of Dentistry, 57, 38-44.
Year 2022, Volume: 9 Issue: 2, 652 - 661, 24.08.2022
https://doi.org/10.15311/selcukdentj.980001

Abstract

Project Number

yoktur.

References

  • KAYNAKÇA Akyildiz, M., & Saroglu Sönmez, I. (2019). comparison of remineralising potential nano silver fluoride, silver diamine fluoride and sodıum fluoride varnish on artifical caries an in viro study. Oral Health Prev Dent, 469-77.
  • Cernigliaro, D., Kumar, A., & Northridge, M. (2019). Caregiver satisfaction with interim silver diamine fluoride applications for their children with caries prior to operating room treatment or sedation. J Public Health Dent ., 286-91.
  • Crystal , Y., & Marghalani , A. (2017). Use of Silver Diamine Fluoride for Dental Caries Management in Children and Adolescents, Including Those with Special Health Care Needs. Pediatr Dent, 135-45.
  • Duangthip , D., Fung , M., Wong , M., Chu , C., & Lo , E. (2017). Adverse Effects of Silver Diamine Fluoride Treatment among Preschool Children. J Dent Res, 395-401.
  • Duker , M., Hayashi, J., Chan , D., Tagami , J., & Sadr, A. (2019). Effect of silver diamine fluoride and potassium iodide on bonding to demineralized dentin. Am J Dent, 32(3), 143-46.
  • Espíndola-Castro, L., Rosenblatt, A., Galembeck, A., & Monteiro, G. (2020). Dentin Staining Caused by Nano-silver Fluoride: A Comparative Study. Oper Dent, 45(4), 435-441.
  • Huebner , C., Milgrom, P., & Cunha-Cruz, J. (2020). Parents' Satisfaction with Silver Diamine Fluoride Treatment of Carious Lesions in Children. J Dent Child, 4-11.
  • Jabin , Z., Vishnupriya, V., & Agarwal, N. (2020). Effect of 38% silver diamine fluoride on control of dental caries in primary dentition: A Systematic review. J Family Med Prim Care, 1302-1307.
  • Jiang , M., Mei , M., Wong , M., Chu , C., & Lo, E. (2020). Effect of silver diamine fluoride solution application on the bond strength of dentine to adhesives and to glass ionomer cements: a systematic review. BMC Oral Health, 20(1).
  • Kucukyilmaz , E., Savas , S., Akcay , M., & Bolukbasi, B. (2016). Effect of silver diamine fluoride and ammonium hexafluorosilicate applications with and without Er:YAG laser irradiation on the microtensile bond strength in sound and caries-affected dentin. Lasers Surg Med, 62-69.
  • Li , Y., Liu, Y., Psoter , W., Nguyen, O., & Bromage , T. (2019). Assessment of the Silver Penetration and Distribution in Carious Lesions of Deciduous Teeth Treated with Silver Diamine Fluoride. Caries Res, 431-440.
  • Luk , K., Niu, J., & Gutknecht, N. (2021). Preventing Enamel Caries Using Carbon Dioxide Laser and Silver Diamine Fluoride. Photobiomodul Photomed Laser Surg.
  • Luk , K., Zhao, I., & Yu , O. (2020). Caries Prevention Effects of Silver Diamine Fluoride with 10,600 nm Carbon Dioxide Laser Irradiation on Dentin. Photobiomodul Photomed Laser Surg, 295-300.
  • Mei , M., Yan , Z., Duangthip , D., Niu , J., & Yu, O. (2020). Effect of silver diamine fluoride on plaque microbiome in children. J. Dent.
  • Quock , R., Barros, J., Yang, S., & Patel, S. (2012). Effect of silver diamine fluoride on microtensile bond strength to dentin. Oper Dent, 37(6), 610-6.
  • Romão, D., Fernández, C., & Santos, L. (2020). Commercial Silver Diamine Fluoride (SDF) Products on Caries Lesion Progression in Primary Enamel: An In Vitro Study. Oral Health Prev Dent, 1025-1029.
  • Timms, L., Sumner, O., Deery , C., & Rogers, H. (2020). Everyone else is using it, so why isn't the UK? Silver diamine fluoride for children and young people. Community Dent Health, 143-49.
  • Turton, B., Horn , R., & Durward , C. (2020). Caries arrest and lesion appearance using two different silver fluoride therapies on primary teeth with and without potassium iodide: 12-month results. Clin Exp Dent Res, 28, 1-11.
  • Yua, O., Mei, M., & Zhao, I. (2018). Remineralisation of enamel with silver diamine fluoride and sodium fluoride. 344-52.
  • Zhao , I., Yin , I., Mei , M., & Lo, E. (2020). Remineralising Dentine Caries Using Sodium Fluoride with Silver Nanoparticles: An In Vitro Study. Filters applied: 1 year. Clear all, 2829-2839.
  • Zhao , I., Chu, S., Yu, O., Mei , M., Chu , C., & Lo , E. (2019). Effect of silver diamine fluoride and potassium iodide on shear bond strength of glass ionomer cements to caries-affected dentine. Int Dent J, 69(5), 341-347.
  • Agob , J., Aref , N., & Al-Wakeel , E. (2018). Effect of casein phosphopeptide-amorphous calcium phosphate on fluoride release and micro-shear bond strength of resin-modified glass ionomer cement in caries-affected dentin.,». Restor Dent Endod, 43(4).
  • Aksrapak, P. (2018). Microtensile Bond Strength Between Glass Ionomer Cement and Silver Diamine Fluoride-Treated Carious Primary Dentin. Pediatric dentistry, 40(4), 291-295.
  • Bahar, A., & Tagomori, S. (1994). The Effect of normal pulsed Nd-YAG laser irradiation on pits and fissures in humman teeth. Caries Research Journal, 28, 460-467.
  • Bau MEYER, J. C. (2018, November 12). Play it SMART:silver diamine fluorideplus ITR for dental caries. http://www.dentistryiq.com adresinden alındı
  • Bimstein, E., & Damm, D. (2018). Human Primary Tooth Histology Six Months after Treatment with Silver Diamine Fluoride. The Journal of Clinical Pediatric Dentistry, 42(6), 442-444.
  • Chaussain-Miller, C., Fioretti, F., Goldberg, M., & Menashi, M. (2006). The Role of matrix metalloproteinases in human caries. Journal of Dental Researh, 85(1), 22-32.
  • Chu, C., & Lo, E. (2008). Microhardness of dentine in primary teeth after topical fluoride applications. Journal of Dentistry, 36(6), 387-91.
  • Chu, c., & Lo, E. (2008). Promoting Caries Arrest in Children with Silver Diamine Fluoride. Oral Health Preventive Dentistry, 6(4), 315-321.
  • Craig, G., Knight, G., & Melntyre, J. (2012). Clinical evaluation of diamine silver fluoride/potassium iodide as a dentine desensitizing agent. A pilot study. Australian DentalJournal, 57(3), 308-11.
  • Crystal, Y., & Niderrman, R. (2019). Evidence-Based Dentistry Update on Silver Diamine Fluoride. Dental the Clinics North America, 63(1), 45-68.
  • Crystal, Y., Janal, M., Hamilton, D., & Niederman, R. (2017). Parental perceptions and acceptance of silver diamine fluoride staining. Journal of the American Dental Association, 148(7), 510-518.
  • DenBesten, P., & Li, W. (2011). chronic fluoride toxicity dental fluorosis. Monographs in Science(22), 81-96.
  • Duangthip, D., Fung, M., Wong, M., Chu, C., & Lo, E. (2018). Adverse Effects of Silver Diamine Fluoride Treatment among Preschool Children. Journal of dental research, 97(4), 395-401.
  • Fancher, M., Fournier, S., Townsend, J., & Lallier, T. (2019). Cytotoxic effects of silver diamine fluoride. Journal of American Dentistry, 32(3), 152-156.
  • Firouzmandi, M., Shafiei, F., Jowkar, Z., & Nazemi, F. (2019). Effect of Silver Diamine Fluoride and Proanthocyanidin on Mechanical Properties of Caries-Affected Dentin. European Journal of Dentistry, 13(2), 255-60.
  • Fung, M., Duangthip, D., Wong, M., Lo, E., & Chu, C. (2016). Arresting dentine caries with different concentra-tion and periodicity of silver diamine fluoride. Clin Trans Res, 143-52.
  • Gao, S., Zhao, I., & Hiraishi, N. (2016). Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children:A Systematic Review. International & American Associations for Dental Research 2016, 1(3), 201-10.
  • Gao, S., Zhao, I., Hirashi, N., Duangthip, D., Mei, M., Lo, E., & Chu, C. (2016). Clinical Trials of Silver Diamine Fluoride in Arresting Caries among Children: A Systematic Review. Journal of Dental Research, 1(3), 201-10.
  • Gotjamanos, T. (1997). Safety İssues Related to the use of silver fluoride in pediatric dentistry. Australia Dental Journal, 42(3), 166-8.
  • Horst, J., Tanzer, J., & Milgrom, P. (2019). fluorides and other preventive strategies for tooth decay. dent clin north am., 62(2), 207-34.
  • Hosoya , Y., Aritomi, K., & Goto, G. (1990). Pulpal response to diammine silver fluoride. (2). Application on exposed pulps]. Shoni Shikagaku Zasshi, 327-37.
  • Hu, S., Meyer, B., & Duggal, M. (2018). A silver renaissance dentistry. European Archives of Paediatric Dentistry, 19(4), 221-227.
  • Kawasaki, A., Suge, T., Ishikawa, K., & Ozaki, K. (2005). Ammonium hexafluorosilicate increased acid resistance of bovine enamel and dentine. JOURNAL OF MATERIALS SCIENCE:, 16(5), 461-466.
  • Knight, G., Mclntyre, J., & Craig, G. (2009). Inability to form a biofilm of Streptococcus mutans on silver fluoride- and potassium iodide-treated demineralized dentin. Quintessence İnternational, 40(2), 155-161.
  • Korwar, A., Sharma, S., & Naseem, S. (2015). Pulp Response to high Fluoride releasing glass ionomer silver diamine fluoride and calcium hydroxide usedfor indrect pulp treatment:an in-vivo comparative study. Contemp Clin Dent, 6(3), 288-92.
  • Law, A., & Messer, H. (2004). An evidence-based analysis of the antibacterial effectiveness of intracanal medicaments. Journal of Endodontics, 10(689-94), 30.
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There are 71 citations in total.

Details

Primary Language Turkish
Subjects Dentistry
Journal Section Review
Authors

Zeynep Uçar 0000-0001-8535-1755

Bahar Melis Akyıldız This is me 0000-0001-9714-7321

Project Number yoktur.
Publication Date August 24, 2022
Submission Date September 22, 2021
Published in Issue Year 2022 Volume: 9 Issue: 2

Cite

Vancouver Uçar Z, Akyıldız BM. ÇOCUK DİŞ HEKİMLİĞİNDE GÜMÜŞ DİAMİN FLORÜR KULLANIMI. Selcuk Dent J. 2022;9(2):652-61.