Knowledge and behavior of dentistry patients about the use and misuse of antibiotics: A cross-sectional study

Year 2022, Volume: 9 Issue: 3, 753 - 762, 26.12.2022

Nilay Er

https://doi.org/10.15311/selcukdentj.1033705

Abstract

Amaç: Bu anket çalışmasının amacı dental enfeksiyonlarda en sık kullanılan ilaçlar olan antibiyotikler hakkında diş hekimliği hastalarının bilgi ve davranışlarının analiz edilmesiyle hatalı ilaç kullanımına yol açan etkenleri ortaya çıkarmaktır.
Yöntem: Bu kesitsel anket çalışması Mart 2019-Haziran 2019 tarihleri arasında Trakya Üniversitesi Diş Hekimliği Fakültesi’ne gelen hastalar arasında gerçekleştirildi. Veriler bir anket kullanılarak toplandı ve istatistiksel analiz için IBM SPSS Statistics 22 (IBM SPSS, Türkiye) kullanılarak analiz edildi. Nitel verilerin ve frekansın karşılaştırılmasında Ki-kare testi, Fisher's Exact testi, Fisher Freeman Halton testi ve Süreklilik (Yates) Düzeltmesi kullanıldı. Anlamlılık p<0.05 düzeyinde değerlendirildi.
Bulgular: Bu çalışmaya toplam 350 gönüllü katıldı. Doktora danışmadan antibiyotik ile kendi kendine tedavi oranı % 31.7 (n=111) ve hasta olmadan evde bulundurmak üzere doktordan antibiyotik isteme oranı % 9.7 (n= 34) olarak bulundu. Katılımcıların % 24,9'u (n=87) şikayetleri bitince antibiyotik kullanmayı bıraktığını ve % 50,6'sı (n=177) diş enfeksiyonlarında verilen antibiyotiklerin diğer enfeksiyonlarda da etkili olduğunu düşündüklerini belirtti. Eğitim seviyesi gruplarının tümünde yüksek oranda antibiyotik kötüye kullanım davranışı bulundu.
Sonuçlar: Bu çalışma sonuçları diş kaynaklı rahatsızlıklardaki antibiyotik kullanımı ile ilgili olarak, hastalar arasında bilgilendirme ve eğitimsel müdahalelere acil bir ihtiyaç olduğunu belirlemiştir.

Keywords

antibiotic use, antimicrobial resistance, dentistry, drug misuse

Knowledge and behavior of dentistry patients about the use and misuse of antibiotics: A cross-sectional study

Abstract

Background: Antibiotics are being used frequently in dental infection and this study focused on the knowledge and behavior on antibiotic use of dentistry patients to reveal major mistakes leading to drug misuse.
Methods: This cross-sectional survey was conducted among Trakya University Faculty of Dentistry patients between March and June 2019. The data were collected using a questionnaire and analyzed using IBM SPSS Statistics 22 (IBM SPSS, Turkey) for statistical analysis. Chi-square test, Fisher's Exact test, Fisher Freeman Halton test, and Continuity (Yates) Correction were used for comparison of qualitative data and frequency. Significance was evaluated at the p<0.05 level.
Results: A total of 350 patients participated in this study. The rate of self-treatment with antibiotics was 31.7% (n=111) and the rate of asking for prescribing antibiotics without being sick is 9.7% (n= 34). 24.9% (n=87) of the participants use antibiotics until their complaints stop. 50.6% (n=177) of the participants think that antibiotics given in dental infections are also effective in other infections. Among the educational backgrounds, high rates of antibiotic misuse behavior were found in all groups.
Conclusion: This study has identified an urgent need for widespread investigations and educational interventions for patients regarding antibiotic usage, especially in dental situations.

Keywords

antibiotic use

References

• 1. Pereira JQ, Silva MT, Galvao TF. Use of antibiotics by adults: a population-based cross-sectional study. Sao Paulo Med J 2018;136:407-413.
• 2. World Health Organisation. Global action plan on antimicrobial resistance. 2015. http://www.who.int/antimicrobial-resistance/publications/global-action-plan/en/ Accessed 22 Jan 2020.
• 3. Jairoun A, Hassan N, Ali A, Jairoun O, Shahwan M. Knowledge, attitude and practice of antibiotic use among university students: a cross-sectional study in UAE. BMC Public Health 2019;19:518.
• 4. Eysenbach G. Improving the quality of Web surveys: the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). J Med Internet Res 2004; 6:e34.
• 5. https://cip.tuik.gov.tr/ Accessed at 15 July 2021.
• 6. Kandelaki K, Lundborg CS, Marrone. Antibiotic use and resistance: a cross-sectional study exploring knowledge and attitudes among school and institution personnel in Tbilisi, Republic of Georgia. BMC Res Notes 2015; 8:495.
• 7. Ventola CL. The antibiotic resistance crisis: part 1: causes and threats. P T 2015;40:277-83.
• 8. Van de Sande-Bruinsma N, Grundmann H, Verloo D, Tiemersma E, Monen J, Goossens H, et al. Antimicrobial drug use and resistance in Europe. Emerg Infect Dis 2008;14:1722-1730.
• 9. Skliros E, Merkouris P, Papazafiropoulou A, Gikas A, Matzouranis G, Papafragos C, et al. Self-medication with antibiotics in rural population in Greece: a cross-sectional multicenter study. BMC Fam Pract 2010;11:58.
• 10. Jamhour A, El-Kheir A, Salameh P, Hanna PA, Mansour H. Antibiotic knowledge and self-medication practices in a developing country: A cross-sectional study. Am J Infect Control 2017;45:384-388.
• 11. Harbarth S, Samore MH. Antimicrobial resistance determinants and future control. Emerg Infect Dis 2005;11:794-801.
• 12. Al-Bakri AG, Bustanji Y, Yousef AM. Community consumption of antibacterial drugs within the Jordanian population: sources, patterns and appropriateness. Int J Antimicrob Agents 2005;26:389-395.
• 13. Berzanskyte A, Valinteliene R, Haaijer-Ruskamp FM, Gurevicius R, Grigoryan L. Self-medication with antibiotics in Lithuania. Int J Occup Med Environ Health 2006;19:246-253.
• 14. Okeke IN, Klugman KP, Bhutta ZA, Duse AG, Jenkins P, O'Brien TF, et al. Antimicrobial resistance in developing countries. Part II: strategies for containment. Lancet Infect Dis 2005;5:568-580.
• 15. Al-Azzam SI, Al-Husein BA, Alzoubi F, Masadeh MM, Al-Horani MA. Self-medication with antibiotics in Jordanian population. Int J Occup Med Environ Health 2007;20:373-380.
• 16. Haque M, Rahman NAA, McKimm J, Binti Abdullah SL, Islam MZ, Zulkifli Z, et al. A cross-sectional study evaluating the knowledge and beliefs about, and the use of antibiotics amongst Malaysian university students. Expert Rev Anti Infect Ther 2019;17:275-284.
• 17. Chandy SJ, Thomas K, Mathai E, Antonisamy B, Holloway KA, Stalsby Lundborg C. Patterns of antibiotic use in the community and challenges of antibiotic surveillance in a lower-middle-income country setting: a repeated cross-sectional study in Vellore, South India. J Antimicrob Chemother 2013;68:229-236.
• 18. Grigoryan L, Haaijer-Ruskamp FM, Burgerhof JG, Mechtler R, Deschepper R, Tambic-Andrasevic A, et al. Self-medication with antimicrobial drugs in Europe. Emerg Infect Dis 2006;12:452-459.
• 19. Grigoryan L, Burgerhof JG, Degener JE, Deschepper R, Lundborg CS, Monnet DL, et al. Determinants of self-medication with antibiotics in Europe: the impact of beliefs, country wealth and the healthcare system. J Antimicrob Chemother 2008;61:1172-1179.
• 20. Wang XM, Zhou XD, Hesketh T. Massive misuse of antibiotics by university students in China: a cross-sectional survey. Lancet 2016;388:S94.
• 21. Peng D, Wang X, Xu Y, Sun C, Zhou X. Antibiotic misuse among university students in developed and less developed regions of China: a cross-sectional survey. Glob Health Action 2018;11:1496973.
• 22. Kardas P, Devine S, Golembesky A, Roberts C. A systematic review and meta-analysis of misuse of antibiotic therapies in the community. Int J Antimicrob Agents. 2005;26:106-113.
• 23. Hafner S, Albittar M, Abdel-Kahaar E, Zolk O. Antibiotic prophylaxis of infective endocarditis in oral and maxillofacial surgery: incomplete implementation of guidelines in everyday clinical practice. Int J Oral Maxillofac Surg 2020;49:522-528.
• 24. American Dental A, American Academy of Orthopedic S. Antibiotic prophylaxis for dental patients with total joint replacements. J Am Dent Assoc 2003;134:895-899.
• 25. Loikas D, Wettermark B, von Euler M, Bergman U, Schenck-Gustafsson K. Differences in drug utilisation between men and women: a cross-sectional analysis of all dispensed drugs in Sweden. BMJ Open 2013;3(5):e002378.
• 26. Serna MC, Ribes E, Real J, Galvan L, Gasco E, Godoy P. High exposure to antibiotics in the population and differences by sex and age. Aten Primaria 2011;43:236-244.
• 27. Hooton TM. Recurrent urinary tract infection in women. Int J Antimicrob Agents 2011;17:259-268.
• 28. Mor A, Froslev T, Thomsen RW, Oteri A, Rijnbeek P, Schink T, et al. Antibiotic use varies substantially among adults: a cross-national study from five European Countries in the ARITMO project. Infection 2015;43:453-472.
• 29. De Jong J, Bos JH, de Vries TW, de Jong-van den Berg LT. Use of antibiotics in rural and urban regions in The Netherlands: an observational drug utilization study. BMC Public Health 2014;14:677.
• 30. Huang Y, Gu J, Zhang M, Ren Z, Yang W, Chen Y, et al. Knowledge, attitude and practice of antibiotics: a questionnaire study among 2500 Chinese students. BMC Med Educ 2013; 13:163.