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Investigation of Osteoradionecrosis Awareness of Dentists in Turkey in Patients with Head and Neck Cancer

Year 2025, Volume: 12 Issue: 1, 1 - 6, 21.04.2025
https://doi.org/10.15311/selcukdentj.1483621

Abstract

Introduction: Head and neck cancers; include cancers in the oral cavity, lip, nasal cavity, salivary glands, pharynx, and larynx. This study aimed to investigate dentists' awareness of osteoradionecrosis, one of the most critical side effects of radiotherapy in patients with head and neck cancer.
Material and Method: In this survey study, dentists from 12 different regions in NUTS-1 determined by TURKSTAT were reached via digital media and their participation in the study was ensured. Participants were asked 25 questions about osteoradionecrosis prepared by reviewing the literature. For the statistical analysis of the data collected from the questionnaires, frequency analysis, and chi-square test were performed with the help of the SPSS 23 package program. A p-value <0.05 was accepted for statistical significance.
Results: A total of 634 participants, including 278 (44%) intern dentists,149 (24%) general practitioner dentists, 128 (20%) doctoral-specialty students, and 79 (12%) specialist dentists, were included in the study. When the data obtained from the study is examined; It was found significant as a result of the analysis that doctorate-specialty students and specialist dentists had more knowledge in the diagnosis of osteoradionecrosis and in the treatment methods (p=0.000<0.050).
Conclusion: Necessary training should be provided both in the undergraduate program and within the framework of continuing education activities to increase the awareness of osteoradionecrosis in general practitioners and intern dentists.

Ethical Statement

This article is not the version of a presentation. This article has not been prepared on the basis of a master’s/ doctoral thesis. It is declared that during the preparation process of this study, scientific and ethical principles were followed and all the studies benefited are stated in the bibliography.

Supporting Institution

None.

Thanks

None.

References

  • 1. Başerer N. Oral Kavite Kanserleri. In: Engin K, Erişen L (eds). Baş- Boyun Kanserleri 1. Baskı. Nobel Matbaacılık. İstanbul. 2003;33-36.
  • 2. Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman. Global cancer statistics . GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018;68(6):394-424.
  • 3. Beyzadeoğlu M., Özyiğit G., Ebruli C. Basic Radiation Oncology. 2010;30,148,155- 169,209-222.
  • 4. Hermans R. Posttreatment imaging of head and neck cancer. Eur J Radiol. 2008;66:501-11.
  • 5. A. Vissink, F.R. Burlage, F.K. Spijkervet, J. Jansma, R.P. Coppes. Prevention and treatment of the consequences of head and neck radiotherapy. Crit Rev Oral Biol Med. 2003;14:213-25.
  • 6. Chronopoulos A, Zarra T, Ehrenfeld M, Otto S. Osteoradionecrosis of the jaws: definition, epidemiology, staging and clinical and radiological findings. A concise review. Int Dent J. 2018;68(1):22- 30.
  • 7. T. Reuther, T. Schuster, U. Mende, A. Kübler. Osteoradionecrosis of t he jaws a s a side e ffect o f radiotherapy o f head and n eck tumour patients–a report of a thirty year retrospective review. Int J Oral Maxillofac Surg. 2003;32(3):289-95.
  • 8. Kün-Darbois, J-D., and F. Fauvel. Medication-related osteonecrosis and osteoradionecrosis of the jaws: Update and current management. Morphologie. 2021;105(349):170-187.
  • 9. GRISAR, K., et al. Osteoradionecrosis and medication-related osteonecrosis of the jaw: similarities and differences. International journal of oral and maxillofacial surgery. 2016;45(12):1592-1599.
  • 10. Pauli, N. Treating radiation-induced trismus in head and neck cancer; Exercise intervention and risk structures. Doctoral Dissertation, University of Gothenburg, Institute of Clinical Sciences. Sweden. 2015:13-41.
  • 11. B.R. Chrcanovic, P. Reher, A.A. Sousa, M. Harris. Osteoradionecrosis of the jaws—a current overview—part 1. Physiopathology and risk and predisposing factors Oral Maxillofac Surg. 2010;14(1):3-16.
  • 12. T.J. Kuo, W.T. Ko, Y.C. Chang, Y.C. Lai, W.C. Huang. Risk of osteoradionecrosis in head and neck cancers Comparison between oral and non-oral cancers. Oral Oncol. 2016;59:10-1.
  • 13. I.-.F. Pereira, R.-.T. Firmino, H.-.C. Meira, B.-.C.E. Vasconcelos, V-R-AS Noronha, V.-.R. Santos. Osteoradionecrosis prevalence and associated factors: a ten years retrospective study. Med Oral Pathol Oral Cirgia Bucal. 2018;23:633-8.
  • 14. J. Dhanda, D. Pasquier, L. Newman, J. Shaw. Current Concepts in Osteoradionecrosis after Head and Neck Radiotherapy. Clin Oncol. 2016;28:459-66 .
  • 15. J.W. Little, C.S. Miller, N.L. Rhodus Cancer and oral care of patients with cancer. Dent. manag. medically compromised patient (9th ed.). Elsevier. St-Louis, Missouri. 2018:512-3.
  • 16. E.V. Kluth, P.R. Jain, R.N. Stuchell, J.C Frich Jr A study of factor& contributing to the development of osteoradionecrosis of the jaws. J Prosthet Dent. 1988;59:194-201.
  • 17. A.A. Owosho, A. Kadempour, S.K. Yom et al. Radiographic osteoradionecrosis of the jaw with intact mucosa Proposal of clinical guidelines for early identification of this condition. Oral Oncol. 2015;51 (12):93-6.
  • 18. R.E. Marx, R. Tursun. Suppurative osteomyelitis, bisphosphonate induced osteonecrosis, osteoradionecrosis: a blinded histopathologic comparison and its implications for the mechanism of each disease. Int J Oral Maxillofac Surg. 2012;41(3):283-289.
  • 19. Curi MM, Dib LL. Osteoradionecrosis of the jaws: a retrospective study of the background factors and treatment in 104 cases. J Oral Maxillofac Surg. 1997;55:540-544.
  • 20. Ajila, V., & Hegde, S. Osteoradionecrosis-a review of clinical features and management. Gülhane Tip Dergisi. 2020;62(4):213.
  • 21. J Dhanda, L Rennie, R. Shaw. Current trends in the medical management of osteoradionecrosis using triple therapy. Br J Oral Maxillofac Surg. 2018;56:401-405.
  • 22. J.A. Regezi, R.M. Courtney, D.A. Kerr. Dental management of patients irradiated for oral cancer Cancer. 1976;38: 994-1000.
  • 23. McLeod and Bater, N.M. McLeod, M.C. Bater Brennan PA. Management of patients at risk of osteoradionecrosis: results of survey of dentists and oral & maxillofacial surgery units in the United Kingdom, a nd s uggestions f or b est p ractice. B r. J . O ral Maxillofac. Surg. 2010;48:301-304.

Baş ve Boyun Kanseri Olan Hastalarda Türkiye’deki Diş Hekimlerinin Osteoradyonekroz Farkındalıklarının Araştırılması

Year 2025, Volume: 12 Issue: 1, 1 - 6, 21.04.2025
https://doi.org/10.15311/selcukdentj.1483621

Abstract

Giriş: Baş ve boyun kanserleri, ağız boşluğunu, dudakları, burun boşluğunu, tükürük bezlerini, farenks ve larinks'i etkileyen kanserleri içerir. Bu çalışmanın amacı, baş ve boyun kanserli hastalarda radyoterapinin en önemli yan etkilerinden biri olan osteoradyonekroz konusunda diş hekimlerinin farkındalığını değerlendirmektir.
Materyal ve Metod: Bu anket çalışmasında, TÜİK tarafından belirlenen NUTS-1'e göre 12 farklı bölgedeki diş hekimleri, çalışmaya katılımlarını sağlamak için dijital ortamlar aracılığıyla iletişime geçildi. Katılımcılara literatür gözden geçirilerek formüle edilen 25 osteoradyonekroz ile ilgili soru soruldu. Anketlerden toplanan verilerin istatistiksel analizi için SPSS 23 yazılım paketi kullanılarak frekans analizi ve ki-kare testi yapıldı. p<0.05 değeri istatistiksel olarak anlamlı kabul edildi.
Bulgular: Çalışmaya toplam 634 katılımcı dahil edildi; bunlar 278 (%44) stajyer diş hekimi, 149 (%24) genel pratisyen diş hekimi, 128 (%20) doktora uzmanlık öğrencisi ve 79 (%12) uzman diş hekimi idi. Çalışmadan toplanan verilerin incelenmesi sonucunda, doktora uzmanlık öğrencileri ve uzman diş hekimlerinin osteoradyonekrozun tanısında ve tedavi yöntemlerinde daha fazla bilgiye sahip görülmüştür (p=0.000<0.050).
Sonuç: Pratisyen ve stajyer diş hekimlerinin osteoradyonekroz farkındalığını artırmak için lisansüstü programlar içinde ve sürekli eğitim faaliyetleri aracılığıyla gerekli eğitimlerin sağlanması faydalı olabilir.

References

  • 1. Başerer N. Oral Kavite Kanserleri. In: Engin K, Erişen L (eds). Baş- Boyun Kanserleri 1. Baskı. Nobel Matbaacılık. İstanbul. 2003;33-36.
  • 2. Jemal, A., Bray, F., Center, M. M., Ferlay, J., Ward, E., & Forman. Global cancer statistics . GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries. CA: a cancer journal for clinicians. 2018;68(6):394-424.
  • 3. Beyzadeoğlu M., Özyiğit G., Ebruli C. Basic Radiation Oncology. 2010;30,148,155- 169,209-222.
  • 4. Hermans R. Posttreatment imaging of head and neck cancer. Eur J Radiol. 2008;66:501-11.
  • 5. A. Vissink, F.R. Burlage, F.K. Spijkervet, J. Jansma, R.P. Coppes. Prevention and treatment of the consequences of head and neck radiotherapy. Crit Rev Oral Biol Med. 2003;14:213-25.
  • 6. Chronopoulos A, Zarra T, Ehrenfeld M, Otto S. Osteoradionecrosis of the jaws: definition, epidemiology, staging and clinical and radiological findings. A concise review. Int Dent J. 2018;68(1):22- 30.
  • 7. T. Reuther, T. Schuster, U. Mende, A. Kübler. Osteoradionecrosis of t he jaws a s a side e ffect o f radiotherapy o f head and n eck tumour patients–a report of a thirty year retrospective review. Int J Oral Maxillofac Surg. 2003;32(3):289-95.
  • 8. Kün-Darbois, J-D., and F. Fauvel. Medication-related osteonecrosis and osteoradionecrosis of the jaws: Update and current management. Morphologie. 2021;105(349):170-187.
  • 9. GRISAR, K., et al. Osteoradionecrosis and medication-related osteonecrosis of the jaw: similarities and differences. International journal of oral and maxillofacial surgery. 2016;45(12):1592-1599.
  • 10. Pauli, N. Treating radiation-induced trismus in head and neck cancer; Exercise intervention and risk structures. Doctoral Dissertation, University of Gothenburg, Institute of Clinical Sciences. Sweden. 2015:13-41.
  • 11. B.R. Chrcanovic, P. Reher, A.A. Sousa, M. Harris. Osteoradionecrosis of the jaws—a current overview—part 1. Physiopathology and risk and predisposing factors Oral Maxillofac Surg. 2010;14(1):3-16.
  • 12. T.J. Kuo, W.T. Ko, Y.C. Chang, Y.C. Lai, W.C. Huang. Risk of osteoradionecrosis in head and neck cancers Comparison between oral and non-oral cancers. Oral Oncol. 2016;59:10-1.
  • 13. I.-.F. Pereira, R.-.T. Firmino, H.-.C. Meira, B.-.C.E. Vasconcelos, V-R-AS Noronha, V.-.R. Santos. Osteoradionecrosis prevalence and associated factors: a ten years retrospective study. Med Oral Pathol Oral Cirgia Bucal. 2018;23:633-8.
  • 14. J. Dhanda, D. Pasquier, L. Newman, J. Shaw. Current Concepts in Osteoradionecrosis after Head and Neck Radiotherapy. Clin Oncol. 2016;28:459-66 .
  • 15. J.W. Little, C.S. Miller, N.L. Rhodus Cancer and oral care of patients with cancer. Dent. manag. medically compromised patient (9th ed.). Elsevier. St-Louis, Missouri. 2018:512-3.
  • 16. E.V. Kluth, P.R. Jain, R.N. Stuchell, J.C Frich Jr A study of factor& contributing to the development of osteoradionecrosis of the jaws. J Prosthet Dent. 1988;59:194-201.
  • 17. A.A. Owosho, A. Kadempour, S.K. Yom et al. Radiographic osteoradionecrosis of the jaw with intact mucosa Proposal of clinical guidelines for early identification of this condition. Oral Oncol. 2015;51 (12):93-6.
  • 18. R.E. Marx, R. Tursun. Suppurative osteomyelitis, bisphosphonate induced osteonecrosis, osteoradionecrosis: a blinded histopathologic comparison and its implications for the mechanism of each disease. Int J Oral Maxillofac Surg. 2012;41(3):283-289.
  • 19. Curi MM, Dib LL. Osteoradionecrosis of the jaws: a retrospective study of the background factors and treatment in 104 cases. J Oral Maxillofac Surg. 1997;55:540-544.
  • 20. Ajila, V., & Hegde, S. Osteoradionecrosis-a review of clinical features and management. Gülhane Tip Dergisi. 2020;62(4):213.
  • 21. J Dhanda, L Rennie, R. Shaw. Current trends in the medical management of osteoradionecrosis using triple therapy. Br J Oral Maxillofac Surg. 2018;56:401-405.
  • 22. J.A. Regezi, R.M. Courtney, D.A. Kerr. Dental management of patients irradiated for oral cancer Cancer. 1976;38: 994-1000.
  • 23. McLeod and Bater, N.M. McLeod, M.C. Bater Brennan PA. Management of patients at risk of osteoradionecrosis: results of survey of dentists and oral & maxillofacial surgery units in the United Kingdom, a nd s uggestions f or b est p ractice. B r. J . O ral Maxillofac. Surg. 2010;48:301-304.
There are 23 citations in total.

Details

Primary Language English
Subjects Oral and Maxillofacial Surgery
Journal Section Research
Authors

Uğur Dolunay 0000-0003-2150-9124

Hasan Küçükkolbaşı 0000-0002-7769-8537

Yunus Akdoğan 0000-0003-3520-7493

Publication Date April 21, 2025
Submission Date May 14, 2024
Acceptance Date August 6, 2024
Published in Issue Year 2025 Volume: 12 Issue: 1

Cite

Vancouver Dolunay U, Küçükkolbaşı H, Akdoğan Y. Investigation of Osteoradionecrosis Awareness of Dentists in Turkey in Patients with Head and Neck Cancer. Selcuk Dent J. 2025;12(1):1-6.