The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee

Mustafa Tawfeeq; İsmail Keskin; Fatma İlhan

The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee

Abstract

Insulin-like growth factors (IGFs) areknown as peptides with important metabolic effects required for cellular growth and metabolism. IGF-I is synthesized in liver tissue under the control of growth hormone (GH) and released to blood. In the process of GH to accelerate growth, IGF-I occupies a large place. IGF-I clearly showed its important effects on the growth of animal studies. In this study, promoter region of the IGF-I gene were amplified by polymerase chain reaction (PCR) in sheep breeds (Akkaraman, Kivircik, Awassi, Sakiz, Daglıc, Morkaraman, MalyaKarayaka (15 to 20 sheep per breed)) reared in Turkey. Informative restriction fragment length polymorphisms (RFLPs) were obtained with HaeII enzyme. The digestion of IGF-I gene with HaeII produced two alleles and three genotypes. Genotype frequencies were 59%, 19%and 22% for AA, BB and AB genotypes, respectively. Allele frequencies were 0.70 for A allele and 0.30 for the B allele. This study indicates the genetic profiles of the IGF-1 gene in native Turkish sheep breeds.

Keywords

Details

Primary Language

English

Subjects

Zootechny (Other)

Journal Section

Research Article

Authors

Mustafa Tawfeeq This is me
Türkiye

İsmail Keskin This is me
Türkiye

Fatma İlhan This is me
Türkiye

Publication Date

December 25, 2020

Submission Date

July 20, 2020

Acceptance Date

-

Published in Issue

Year 2020 Volume: 34 Number: 3

IZ

https://izlik.org/JA26KH24ZU

Cite

RIS / Bibtex

APA

Tawfeeq, M., Keskin, İ., & İlhan, F. (2020). The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee. Selcuk Journal of Agriculture and Food Sciences, 34(3), 189-192. https://izlik.org/JA26KH24ZU

AMA

1.Tawfeeq M, Keskin İ, İlhan F. The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee. Selcuk J Agr Food Sci. 2020;34(3):189-192. https://izlik.org/JA26KH24ZU

Chicago

Tawfeeq, Mustafa, İsmail Keskin, and Fatma İlhan. 2020. “The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee”. Selcuk Journal of Agriculture and Food Sciences 34 (3): 189-92. https://izlik.org/JA26KH24ZU.

EndNote

Tawfeeq M, Keskin İ, İlhan F (December 1, 2020) The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee. Selcuk Journal of Agriculture and Food Sciences 34 3 189–192.

IEEE

[1]M. Tawfeeq, İ. Keskin, and F. İlhan, “The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee”, Selcuk J Agr Food Sci, vol. 34, no. 3, pp. 189–192, Dec. 2020, [Online]. Available: https://izlik.org/JA26KH24ZU

ISNAD

Tawfeeq, Mustafa - Keskin, İsmail - İlhan, Fatma. “The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee”. Selcuk Journal of Agriculture and Food Sciences 34/3 (December 1, 2020): 189-192. https://izlik.org/JA26KH24ZU.

JAMA

1.Tawfeeq M, Keskin İ, İlhan F. The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee. Selcuk J Agr Food Sci. 2020;34:189–192.

MLA

Tawfeeq, Mustafa, et al. “The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee”. Selcuk Journal of Agriculture and Food Sciences, vol. 34, no. 3, Dec. 2020, pp. 189-92, https://izlik.org/JA26KH24ZU.

Vancouver

1.Mustafa Tawfeeq, İsmail Keskin, Fatma İlhan. The Identification of Genetic Variation in Insulin-Like Growth Factors-I (IGF-I) Gene Region in Some Turkish Shee. Selcuk J Agr Food Sci [Internet]. 2020 Dec. 1;34(3):189-92. Available from: https://izlik.org/JA26KH24ZU