Primer İmmün Yetmezlik Hastalıklarında Cilt Bulguları

Year 2022, , 349 - 354, 30.06.2022

Öner Özdemir

https://doi.org/10.31832/smj.1025702

Abstract

Primer immün yetmezlik hastalık tipleri günümüzde bilindiği gibi 400 hastalığı geçmiş bulunmaktadır. Farkındalığın artması ve tanı yöntemlerinin gelişmesi ile nadir olarak görülmekten çıkmışlar ve sık görülen hastalıklar haline gelmeye başlamışlardır. Bu hastalıklara cilt bulguları açısından yaklaşmak ve tanımak bu derlemenin asıl amacıdır. Primer immün yetmezlik hastalıklarının 10 uyarıcı işaretlerinden ikisi cilt bulgularından olmakla beraber sadece (bakteriyel ya da fungal) enfeksiyöz cilt bulgularını düşündürtmektedir. Bunlardan ilki tekrarlayan derin cilt abseleri ve diğeri cilt üzerindeki persistan mantar enfeksiyonu (tinea / dermatofitoz) olmasıdır. Cilt bulgularının sık olarak primer immün yetmezlik hastalıklarında görüldüğü bilinmelidir. En sık enfeksiyonlara (bakteriyel) ait bulgular görünmesine rağmen, onu non-enfeksiyöz tipte immüno-alerjik bulgu olarak egzama (atopik dermatit) izler. İmmüno-alerjik olmayan bulgular ise epidermal displazi, telenjiektazi vb. belirtilerdir. Bu deri belirtileri, bazen ilk geliş bulgusu olabilir. Her zaman bu bulgular çok özgün olmayabilir. Bu cilt bulgularıyla beraber özellikle büyüme geriliği ya da çoklu sistem tutulumu varsa, yine bu cilt bulgusu rekurrent ve tedaviye dirençli (refrakter) ise mutlaka primer immün yetmezlik hastalığı düşünülmeli ve var olup olmadığı araştırılmalıdır.

Keywords

cilt, immünyetmezlik, granülom, eritrodermi

Supporting Institution

yok

Project Number

yok

Thanks

yok

References

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