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Tüberkülozda ülkemiz verilerine güncel bir bakış

Year 2022, , 586 - 595, 29.09.2022
https://doi.org/10.31832/smj.1078274

Abstract

Tüberküloz, Mycobacterium tuberculosis kompleks tarafından oluşturulan granülomatöz enfeksiyondur. Tüberküloz basili, dünya genelinde çok fazla kişide görülür ancak enfeksiyon oluşturma potansiyeli düşüktür. Enfeksiyon en sık az gelişmiş ülkelerde görülmekle birlikte, gelişmiş ülkelerde kentleşmenin yükselmesi ile toplu yaşam alanlarının ve buralarda zaman geçiren birey sayısında artış nedeni ile vakalar artmıştır. Dünya Sağlık Örgütü’nün tüberkülozu bitirme politikası gereğince olgu sayıları yakından kontrol edilmektedir. Dünya genelinde erişkin erkeklerde daha fazla oranda görülmektedir. HIV pozitif bireylerin tüberküloza olan hassasiyetleri bilinirken 2019 yılı içinde ortaya çıkan yeni tip Coronavirus, tüberküloz kaynaklı ölüm vakalarında artışa neden olmuştur. Vaka sayılarındaki artış ilaç tedavisi alan birey sayısının artmasına ve hastaların medikal takiplerinde aksaklıklar olmasına neden olmaktadır. İlaç kullanımının bırakılması en sık ilaç direncine sebep olan etkindir. Tüberküloz geçmişte olduğu gibi günümüzde de küresel halk sağlığı problemlerinin ilk sıralarında yer almaktadır. Yapılan çalışmalar ve alınan önlemler ile birlikte vaka sayılarında azalma trendi devam etmektedir. Bu azalışın sürekliliği için çalışmalar titizlikle devam etmelidir.

References

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Year 2022, , 586 - 595, 29.09.2022
https://doi.org/10.31832/smj.1078274

Abstract

References

  • Bansal LK, Gupta S, Gupta AK, Chaudhary P. Thyroid tuberculosis. Indian J Tuberc. 2021 Apr;68(2):272-278. doi: 10.1016/j.ijtb.2020.09.006. Epub 2020 Sep 12. PMID: 33845964.
  • Baylan O. Çok ilaca dirençli tüberkülozdan sonra yaygın ilaca dirençli ve tüm ilaçlara dirençli tüberküloz formları: Eski hastalığın yeni yüzleri. Mikrobiyol Bul 2011; 45(1): 181-95
  • Bektöre B, Haznedaroğlu T, Baylan O, Ozyurt M, Ozkütük N, Satana D, Cavuşoğlu C, Seber E. Çok İlaca Dirençli Tüberküloz İzolatlarında Yaygın İlaç Direncinin Araştırılması [Investigation of extensive drug resistance in multidrug resistance tuberculosis isolates]. Mikrobiyol Bul. 2013 Jan;47(1):59-70. Turkish. doi: 10.5578/mb.4229. PMID: 23390903
  • Beyrer C, Shisana O, Baral SD, Milsana K, Mayer KH, Pozniak A, Walker BD, Mboup S, Sohn AH, Serwadda D, Rees H, Dvoriak S, Warren M, Thiam S, El-Sadr WM, Hospital X, Ryan O, Thomson N, Bekker LG. The science of Durban, AIDS 2016. J Int AIDS Soc. 2017 Jun 30;20(1):21781. doi: 10.7448/IAS.20.1.21781. PMID: 28692209; PMCID: PMC5515038.
  • Boeree MJ, Diacon AH, Dawson R, Narunsky K, du Bois J, Venter A, Phillips PP, Gillespie SH, McHugh TD, Hoelscher M, Heinrich N, Rehal S, van Soolingen D, van Ingen J, Magis-Escurra C, Burger D, Plemper van Balen G, Aarnoutse RE; PanACEA Consortium. A dose-ranging trial to optimize the dose of rifampin in the treatment of tuberculosis. Am J Respir Crit Care Med. 2015 May 1;191(9):1058-65. doi: 10.1164/rccm.201407-1264OC. PMID: 25654354.
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  • Churchyard G, Kim P, Shah NS, Rustomjee R, Gandhi N, Mathema B, Dowdy D, Kasmar A, Cardenas V. What We Know About Tuberculosis Transmission: An Overview. J Infect Dis. 2017 Nov 3;216(suppl_6):S629-S635. doi: 10.1093/infdis/jix362. PMID: 29112747; PMCID: PMC5791742.
  • D'Ambrosio L, Centis R, Tiberi S, Tadolini M, Dalcolmo M, Rendon A, Esposito S, Migliori GB. Delamanid and bedaquiline to treat multidrug-resistant and extensively drug-resistant tuberculosis in children: a systematic review. J Thorac Dis. 2017 Jul;9(7):2093-2101. doi: 10.21037/jtd.2017.06.16. PMID: 28840010; PMCID: PMC5542985.
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  • Forrellad MA, Klepp LI, Gioffré A, et al. Virulence factors of the Mycobacterium tuberculosis complex. Virulence. 2013;4(1):3-66. doi:10.4161/viru.22329
  • Furin J, Cox H, Pai M. Tuberculosis. Lancet. 2019 Apr 20;393(10181):1642-1656. doi: 10.1016/S0140-6736(19)30308-3. Epub 2019 Mar 20. PMID: 30904262.
  • Githinji LN, Gray DM, Zar HJ. Lung function in HIV-infected children and adolescents. Pneumonia (Nathan). 2018 Jun 25;10:6. doi: 10.1186/s41479-018-0050-9. PMID: 29984134; PMCID: PMC6016126.
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  • Influenza Raporu. Türküye Halk Sağlığı Genel Müdürlüğü https://grip.gov.tr/depo/influenzaraporu/2022/Haftalik_InfluenzaGrip_Surveyans Raporu_2021_51._Hafta_431b4.pdf Erişim: 10.01.2022
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  • Jha SK, Rathish B. Genitourinary Tuberculosis. 2022 Jan 7. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2022 Jan–. PMID: 32491490.
  • Jo KW, Yoo JW, Hong Y, Lee JS, Lee SD, Kim WS, Kim DS, Shim TS. Risk factors for 1-year relapse of pulmonary tuberculosis treated with a 6-month daily regimen. Respir Med. 2014 Apr;108(4):654-9. doi: 10.1016/j.rmed.2014.01.010. Epub 2014 Jan 27. PMID: 24518046.
  • Lawn SD, Zumla AI. Tuberculosis. Lancet. 2011 Jul 2;378(9785):57-72. doi: 10.1016/S0140-6736(10)62173-3. Epub 2011 Mar 21. PMID: 21420161.
  • Low M. The tuberculosis treatment pipeline: a breakthrough year for the treatment of XDR-TB. July 2017. http://www.pipelinereport. org/2017/tbtx. Erişim 10.01.2022.
  • MacPherson P, Lebina L, Motsomi K, Bosch Z, Milovanovic M, Ratsela A, Lala S, Variava E, Golub JE, Webb EL, Martinson NA. Prevalence and risk factors for latent tuberculosis infection among household contacts of index cases in two South African provinces: Analysis of baseline data from a cluster-randomised trial. PLoS One. 2020 Mar 17;15(3):e0230376. doi: 10.1371/journal.pone.0230376. PMID: 32182274; PMCID: PMC7077873.
  • Mbuagbaw L. A review of available evidence on the use of bedaquiline in the treatment of multidrug-resistant tuberculosis: data analysis report. 2017. http://www.who.int/tuberculosis/publications/2017/Appendix_GDGReport_Bedaquiline.pdf. Erişim: 10.01.2022
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  • Nathavitharana RR, Friedland JS. A tale of two global emergencies: tuberculosis control efforts can learn from the Ebola outbreak. Eur Respir J. 2015 Aug;46(2):293-6. doi: 10.1183/13993003.00436-2015. PMID: 26232473.
  • Ndjeka N, Conradie F, Schnippel K, Hughes J, Bantubani N, Ferreira H, Maartens G, Mametja D, Meintjes G, Padanilam X, Variava E, Pym A, Pillay Y. Treatment of drug-resistant tuberculosis with bedaquiline in a high HIV prevalence setting: an interim cohort analysis. Int J Tuberc Lung Dis. 2015 Aug;19(8):979-85. doi: 10.5588/ijtld.14.0944. PMID: 26162365.
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Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Articles
Authors

Ahmet Aktaş 0000-0003-3243-6338

Yaşar Nakipoğlu 0000-0001-7979-7291

Dilek Şatana 0000-0002-8827-1504

Publication Date September 29, 2022
Submission Date February 28, 2022
Published in Issue Year 2022

Cite

AMA Aktaş A, Nakipoğlu Y, Şatana D. Tüberkülozda ülkemiz verilerine güncel bir bakış. Sakarya Tıp Dergisi. September 2022;12(3):586-595. doi:10.31832/smj.1078274

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