Retrospective observation of our breast cancer patients

Year 2015, , 82 - 86, 07.09.2015

Hasan Ergenç Serdar Olt Özlem Uysal Sönmez Ali Tamer Aysel Gürkan Toçoğlu , Sümeyye Korkmaz

https://doi.org/10.5505/sakaryamj.2015.38233

Abstract

Breast cancer is the one of the most common types of cancer which affects women's health in many countries. However, it is likely to be diagnosed early by the screening methods and to treat the disease. It is possible for the patients to be diagnosed in early term by screening programs and to be treated. In this study, we aimed to presenting demographic, clinical and histopathological features of 150 patients diagnosed and followed as breast cancer in our Oncology Clinic between the years 2011-2013 by comparing with the recent literature data. The mean age patients were 58 years. 68 of the patients (45.3%) were premenopausal. The number of the patients with a family history of breast cancer was noted as 13 (8.7%). It was determined that the number of the patients with oestrogen receptor positivity was 100 (66.7%), progesterone receptor positivity was 87(58%), C-Erb b2 positivity was 38 (25.3%). With regard to the histopathological types of the patients, it was determined that the most frequent types were invasive ductal carcinoma (81.3%) and invasive lobular carcinoma ( 8.7%). Considering to the diagnosis age of 52 in our study, we wanted to highlight that mammography screening after the age of 45 will provide apportunities to identify at an early stage.

Keywords

Breast cancer, Intraductal carcinoma, Intralobular carcinoma

Meme kanserli hastalarımızın geriye dönük değerlendirilmesi

Abstract

Meme kanseri birçok ülkede kadın sağlığını etkileyen ve yaygın olarak görülen kanser türlerinden biridir. Ancak hastalığın erken tanıya yönelik tarama yöntemleri ile tedavisi de olasıdır. Tarama programları ile hastaların erken dönemde tanı alması ve tedavi görmesi mümkündür. Burada kliniğimizde 2011-2013 yılları arasında Onkoloji kliniğimizde meme kanseri tanısı konan ve takip edilen 150 hastanın, demografik,klinik ve histopatolojik özelliklerini güncel literatür bilgileri ile karşılaştırarak sunmayı amaçladık. Çalışmaya dahil edilen 150 meme kanserli hastanın yaş ortalaması 58, tanı yaşı ortalaması 52, menopoz yaşı ortalaması 47, menarş yaşı ortalaması 13, doğum sayısı ortalama 2 ve ilk çocuğunu doğurma yaşı ortalama 22.5 olarak kaydedildi. Hastaların 68 (%45.3)'i premenopozal ve 82 (54.7)'si postmenopozal idi. Hastaların 19 (%12.7)'u OKS, 6 (%4)'sı HRT, 13 (%8,7)'ü sigara ve 1 (%0.7)'i alkol kullanıyordu. Aile öyküsünde meme kanser olan hasta sayısı 13 (%8.7) olarak kayıt edildi. Östrojen reseptör pozitifliği olan hasta sayısı 100 (%66,7), progesteron reseptör pozitifliği olan hasta sayısı 87 (%58), Cerb b2 pozitifliği 38 (%25.3) olarak tespit edildi. Hastaların histopatolojik tiplerine bakıldığında en sık invaziv duktal karsinom (%81.3) ve invaziv lobuler karsinom (8.7) olduğu saptandı. Sonuç olarak hastalarımızın 52 olan tanı yaşına bakıldığında 45 yaşından sonra yapılacak olan mamografi taramalarıyla Meme Kanserli hastalara metastaz gelişmeden tanı konulabileceği gerçeğini vurgulamak istedik.

Keywords

Meme Kanseri, İntraduktal karsinom, İntralobüler Karsinom

References

• 1. Greenlee RT, Hill-Harmon MB, Murray T, Thun M. Cancer statistics, 2001. CA Cancer J Clin, 2001; 51:15-36.
• 2. Öztop İ, Alakavuklar M. Chemotherapy in metastatic breast cancer. Haematology-Oncology Updated compilation journal 2001; 3: 128-36.
• 3. Pak I. Prognostic factors in early stage breast cancer, Haematology-Oncology Updated compilation journal, 2001; 3: 79-83.
• 4. Tuncer M. Significance of cancer in Turkey, the burden of disease and cancer control policies (Volume 74). In: Tuncer M., eds. Cancer Control in Turkey, Ankara, Onur Press, Health Ministry Publication, 2008: 5-9.
• 5. Yeter K.Effect of Training Provided for the Patients Receiving Chemotherapy on the Quality of Life. Unpublished Master’s Thesis, Eskişehir, Eskişehir Osmangazi University, 2006.
• 6. Bektaş Aydın H, Akdemir A. Assessment of Functional Status of the Patients with Cancer. Turkish Clinics J Med Sci 2006;26:448-499.
• 7. Pınar R, Salepci T, Afşar F. Assessment of quality of life in Turkish patients with cancer. Turkish Journal of Cancer 2003,33(2):96-101.
• 8. Ozmen V. Breast cancer in the world and turkey. The Journal of Breast Health 2008; 4(1):7-12.
• 9. Eti Aslan F, Gurkan A. Risk Level of Breast Cancer in Women.The Journal of Breast Health2007;3 (2):63-68. 10. Karamanoğlu Yavuz A, Gok Ozer F. Home Care of Patients with Mastectomy. The Journal of Breast Health 2008;4(1):3-8.
• 11. The Health Ministry of Turkish Republic, Distribution of Cancer Frequency According to Organs and the most frequent 10 types of cancer seen in women, http:// www. saglık. gov.tr. 2001.
• 12. Vogel V. Assessing risk of breast cancer. Postgraduate Medicine 1999; 105:63-69.
• 13. Baron RH, Walsh A. Facts everyone should know about breast. AJN 1995; July:29-33.
• 14. Ries LAG, Eisner MP, Kosary CL, Hankey BF, Miller BA, Clegg L, Edwards,BK (eds). SEER Cancer Statistics Review, 1973-1998, National Cancer Institute, Bethesda, MD.2001.
• 15. Demographic and Health Survey 1998. Hacettepe University Institute of Population Studies, Ankara Turkey, 1999. 16. Henderson IC. Risk factors for breast cancer. Cancer 1993; 71: 2127-2140.
• 17. Weber J, Kelley J. Hearth Assessment in Nursing, LippincottRoven Publishers, Philadelphia, 1998.
• 18. Lee SY, Kim MT, Kim SW, Song MS, Yoon SJ. Effect of lifetime lactation on breast cancer risk: a Korean women’ s cohort study. Int J Cancer 2003; 105 (3): 390- 393.
• 19. Brinton LA, Potischman NA, Swanson CA, Schoenberg JB, Coates R, Gammon MD, Malone KE, Stanford JL, Dailing JR. Breast- feeding and breast cancer risk. Cancer Causes Control 1995; 6 (3):199- 208.
• 20. Mincey BA. Genetics and the management in women at high risk for breast cancer. Oncologist 2003; 8(5): 466-473.
• 21. McCredie M, Paul C, Skegg DC, Williams S. Family history and risk of breast cancer in New Zealand. Int J Cancer 1997; 73(4): 503- 507.
• 22. Özgün H, Soyder A, Tunçyürek P. The factors affecting delayed application in breast cancer. The Journal of Breast Health2009:5, Sayı 2 : 087-091.
• 23. Dolgun E,Kabataş MS, Ertem G Analysis of efficiency ofplanned training provided for the women aged 20 and over about breast self-examination.The Journal of Breast Health2009;5:141-147.
• 24. Spence WR. Health EDCO. A Division of WRS Group, Inc, Waco, Texas, 2000.
• 25. National Family Planning, Service Guide. Volume 3, Damla Press, Volum I, Ankara, 2000.
• 26. Epstein SA, Lin TH, Audrain J, Stefanek M, Rimer B, Lerman C. High-risk breast cancer consortium. Psychosomatics 1997; 38: 253-261.