The Effects of Metabolic Syndrome on Aortic Distensibility in Patients with Angiographically Normal Coronary Arteries

Abstract

Objective: In this study we aimed to investigate the parameters of aortic stiffness that were measured angiographically and the factors that effect these parameters in patients diagnosed as having metabolic syndrome and whose coronary arteries were normal angiographically. Materials and Methods: Thirty patients with metabolic syndrome and twenty patients without metabolic syndrome were included. Hemodynamic measurements were made during cardiac catheterization while the patients were in supine position. The systolic and diastolic diameters of aorta and parameters associated with aortic stiffness aortic strain and distensibility were measured.Results: When compared with the control group the systolic and diastolic blood pressure, pulse pressure, waist circumference, triglyceride and fasting plasma glucose levels were higher and HDL cholesterol level was lower in the metabolic syndrome group. Aortic strain was higher in the metabolic syndrome group but the statistical relation was non-significant (p=0,181). Moreover the distensibility was lower in the metabolic syndrome group and the statistical relation was significant (p

Keywords

• Metabolic syndrome, aortic function, arterial stifness

Koroner Arterler Normal Olan Hastalarda Metabolik Sendromun Aortik Distensibilite Üzerine Etkisi

Abstract

Amaç: Bu çalışmada, metabolik sendrom tanısı alan ve anjiyografik olarak koroner arterleri normal saptanan hastalarda metabolik sendromun invazif olarak ölçülmüş aort sertlik parametrelerine olan etkilerini ortaya koymayı amaçladık.Gereç ve Yöntemler: Çalışmaya metabolik sendrom tanısı konan 30 hasta ve kontrol grubu olarak metabolik sendrom tanısı bulunmayan 20 hasta alındı. Hemodinamik ölçümler hasta yatar pozisyonda kardiyak kateterizasyon yapımı esnasında değerlendirildi. Aort sistolik ve diyastolik çapları ölçüldü ve aort sertliğinin göstergeleri olan aort gerilimi ve esneyebilirliği hesaplandı.Bulgular: Metabolik sendrom grubunda, kontrol grubu ile karşılaştırıldığında beklendiği üzere sistolik ve diyastolik kan basıncı, nabız basıncı, bel çevresi, trigliserid düzeyi, açlık kan şekeri değerleri daha yüksek, HDL-kolesterol düzeyleri düşük bulundu. Metabolik sendrom grubunda aort gerilimi istatistiksel olarak anlamlı olmamakla birlikte daha yüksek saptandı(p=0.181). Aort esneyebiliriği ise istatistiksel olarak anlamlı olarak daha düşük idi(p

Keywords

• Metabolik sendrom, aortik fonksiyon, arteryel sertlik

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