ABDOMINAL AORTIC ANEURYSM OCCURENCE AND RISK FACTORS IN HEMODIALYSIS PATIENTS

Year 2018, , 14 - 19, 26.03.2018

Altay Kandemir , Gökhan Nergizoğlu

https://doi.org/10.31832/smj.380824

Abstract

Objective: Frequency
and age-standardized mortality rate are increasing for asymptomatic and
ruptured abdominal aortic aneurysm (AAA). Because traditional risk factors and
chronic renal failure related risk factors in hemodialysis patients are
recognized as the main factors in AAA etiopathogenesis, in this study we aimed
to determine the frequency of AAA by 
ultrasonography (USG).

Materials and Methods: A
total of 647 patients (341 men/306 women, 58.3±11.6 years of age) from 8
dialysis centers and 185 control subjects (102 men/83 women, 57.4±9.6 years of
age) were included in the study. Transverse diameter and anterior-posterior
diameter measurements of infrarenal aorta and suprarenal aorta were performed
with B-Mode gray scale ultrasound projection. The relationship between
demographic and biochemical parameters of patients and abdominal aortic
aneurysm was also evaluated.

Results: The frequency of AAA
was 8.2% in hemodialysis patients while 3.8% in control group (p<0.05). Men
displayed a higher risk of AAA than women (p<0.05). Univariate analysis of
hemodialysis patients and study parameters revealed a significant relation
between age, gender, hyperlipidemia and parathormone levels. However,
independent variables were determined as only age, male gender and diabetes
mellitus in multivariate analysis.

Conclusion: In our
study, the risk of AAA was found to increase in hemodialysis patients and
advanced age, male gender, and diabetes mellitus were determined as the
prominent factors . Our findings suggest that the patients having these risk
factors may have an improved life span with early detection and timely treatment
of abdominal aortic aneurysm cases by regular screening programs in
hemodialysis. 

Keywords

Abdominal Aortic Aneurysm, Ultrasonography, Chronic renal failure

Hemodiyaliz Hastalarında Abdominal Aort Anevrizması Sıklığı ve Risk Faktörleri

Abstract

Amaç: Asemptomatik ve rüptüre
abdominal aort anevrizması (AAA) sıklığı ve yaş-standartize mortalitesi giderek
artmaktadır. Biz bu çalışmada
hemodiyaliz tedavisi alan hastalarda geleneksel risk faktörleri ve kronik
böbrek yetmezliği ile ilişkili risk faktörlerinin AAA etiopatogenezinde de
temel faktörler olması nedeniyle ultrasonografi (USG) ile AAA sıklığını
saptamayı amaçladık.

Gereç-Yöntemler: Toplam 8 diyaliz merkezinden 647 (341 erkek/306
kadın, 58.3±11.6 yıl ) hasta ve 185 (102 erkek/83 kadın, 57.4±9.6 yıl) kontrol
çalışmaya alındı. B-Mode gri skala Ultrasonografik projeksiyon ile infrarenal
aorta ve suprarenal aortanın transvers çap ve anterior-posterior çap ölçümleri
yapıldı. Ayrıca hastaların demografik ve biyokimyasal parametreleri ile
abdominal aort anevrizması arasındaki ilişki değerlendirildi.

Bulgular: Hemodiyaliz hastalarında abdominal aorta
anevrizması sıklığı %8.2 iken kontrol grubunda %3.8 idi (p<0.05). Cinsiyete
göre değerelendirildiğinde erkeklerde anevrizma riski daha yüksek saptandı
(p<0.05). Univariate analizde hemodiyaliz hastaları ve çalışma parametreleri
incelendiğinde yaş, cinsiyet, hiperlipidemi ve parathormon düzeyi arasında
anlamlı ilişki saptandı. Ancak multivariate analizde bağımsız değişkenler
yalnızca yaş, erkek cinsiyet ve diyabetes mellitus saptandı.

Sonuç: Çalışmamızda hemodiyaliz hastalarında abdominal
aort anevrizması riskinin arttığı ve risk artışında en temel faktörler olarak
ileri yaş, erkek cinsiyet ve diyabet mellitus varlığının ön planda çıktığını
saptadık. Bulgularımız, bu risk faktörlerine sahip hemodiyaliz hastalarında
düzenli tarama programları ile abdominal aort anevrizması olgularının
saptanarak gerekli girişimlerin yapılmasının yaşam sürelerine katkıda
bulunabileceğini düşündürmektedir.

Keywords

Abdominal aort anevrizması, Ultrasonografi, Kronik böbrek yetmezliği

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