İnsan Anellovirüsleri

Year 2018, , 462 - 469, 30.09.2018

Semra Öz , Merve Pilavcı Adıgül , Mustafa Altındiş

https://doi.org/10.31832/smj.448521

Abstract

Çeşitli
biyolojik insan numuneleri üzerinde yüksek verimli sekanslamanın yaygın
kullanımı sonucunda bilinen viral tiplerin dağılımı değişmiş ve birçok yeni
virüs ortaya çıkmıştır.İnsanları enfekte ettiği bilinen bu virüs
ailesi, Alphatorquevirüs genusundan Torque teno virüs, Betatorquevirüs
genusundan Torque teno mini virüs ve Gammatorquevirüs genusundan Torque teno
midi virüsü içermektedir. Dünya nüfusunda Anellovirüs prevalansı oldukça
yüksektir. Bu virüslerin insanlar için patojeniteleri hala net olarak açıklanamamıştır.
Yapılan çalışmalarda Anellovirüslerin başta hepatit olmak üzere solunumsal,
hematopoetik, bağışıklık sistemi ve kanser gibi birkaç hastalık ile ilişkili
olduğu görülmüş olmakla birlikte kesin veriler bulunmamaktadır. Temel viroloji
ve immünoloji alanında yapılacak daha kapsamlı ve verimli çalışmalar ile
Anellovirüsler hakkında bilgilerimiz artacaktır ve çözüm bekleyen sorularımız
cevap bulacaktır.

Keywords

Anellovirüs; Torque teno virüs; virom

Human Anelloviruses

Abstract

The widespread use of high-throughput sequencing on a
variety of biological human samples has altered the distribution of known viral
types, many new viruses have emerged. Torque teno viruses, closely related to
each other within the members of the Anelloviridae family, are recently
discovered viruses. It contains Torque teno virus from Alphatorquevirus genus,
Torque teno midi virus from Betatorquevirus genus, Torque teno midi virus from
Gammatorquevirus genus which are known to infect humans. The prevalence of
Anellovirus in the world is very high. The pathogenicity of these viruses to
humans is still unclear. Studies have shown that Anelloviruses are associated
with several diseases, especially hepatitis, such as respiratory, hematopoietic,
immune system, cancer but we still don’t have the exact data. As a result of
more comprehensive and efficient work in the field of basic virology and
immunology, we will increase our knowledge of Anelloviruses, answer our
questions that are pending.

References

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