Vitiligo Hastalarında İnce Lif Nöropatisinin Değerlendirilmesi

Year 2019, , 148 - 153, 20.03.2019

Bahar Sevimli Dikicier Bekir Enes Demiryürek

https://doi.org/10.31832/smj.453290

Abstract

Amaç: Bu çalışma, normal standart sinir iletim çalışmaları olan vitiligo
hastalarında ince lif nöropatisini tespit etmek için tasarlanmıştır.

Meteryal Metod: Bu vaka- kontrol çalışması Mart 2016-Haziran 2016 tarihleri ​​arasında
Sakarya Üniversitesi Tıp Fakültesi Eğitim ve Araştırma Hastanesi Nöroloji
Anabilim Dalı'nda ENMG laboratuvarında gerçekleştirildi. Çalışmaya 123 vitiligo
hastasından dışlama kriterlerine göre seçilmiş 18-60 yaş arasında 40 vitiligo
hastası ile kontrol amaçlı yaşları ve cinsiyetleri eşleştirilmiş 40 sağlıklı
birey dahil edildi. Katılımcılar iki gruba ayrıldı (vitiligo ve kontrol
grupları). Katılımcıların demografik verileri kaydedildi. İnce lif iletimini
değerlendirmek için kutanöz sessiz period  (KSP) iletim çalışması yapıldı.
Vitiligo şiddeti vitiligo alan skorlama indeksi ile değerlendirildi.

Bulgular: Üst ve alt ekstremitelerin KSP distal latans ve süre değerleri iki
grupta benzerdi (vitiligo ve kontrol). Vitiligo hastalarında hastalığın şiddeti
ve süresi ile üst ve alt ekstremitelerin KSP değerleri arasında ilişki
saptanmadı.

Sonuç: Bu çalışmanın, vitiligonun her bir: miyelinli A delta lifleri ve küçük
lifler olan demiyelinize C lifleri üzerindeki etkilerini gözlemlememize izin
verdiği için değerli olduğunu düşünmekteyiz. 

Keywords

kutanöz sessiz period; vitiligo; ince lif nöropatisi

Thin Fiber Neuropathy Associated with Vitiligo

Abstract

Objective:
This study is designed to detect thin fiber
neuropathy, if any with patients who had vitiligo and had normal standard nerve
conduction studies.

Matherials
and Methods: This
case - control study was conducted between March 2016-June 2016 in ENMG
laboratory of our neurology clinic. Amoung 123 vitiligo
patients, 40vitiligo patients between ages 18-60 without
evident neuropathy by standard nerve conduction studies
were included in this study. Furthermore 40
healthy individuals without vitiligo or any neuropathy with matching age and
gender were included in this study. All participants divided into two groups
(vitiligo and control groups). Demographic data were
recorded with weight, height, body mass index (BMI) data of participants. Cutaneous
silent period conduction study was performed in median and sural nerves to
evaluate small fiber conduction.

Results:
CSP duration and distal latency measurements
abductor pollicis braves muscle on the upper extremity and tibialis anterior
muscle on the lower extremity were similar in both CTS and control groups.
Our findings show no
association with vitiligo and small fiber neuropathy,  

Conclusion:
We suppose that this
study is valuable for allowing us to observe the effects of vitiligo on each:
myelinated A delta fibers and demyelinated C fibers, which are small fibers.

Keywords

cutaneous silent period; vitiligo; thin fiber neuropathy

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