Research Article
BibTex RIS Cite
Year 2019, , 266 - 271, 28.06.2019
https://doi.org/10.31832/smj.532943

Abstract

References

  • 1. Le Goff MM, Bishop PN. Adult vitreous structure and postnatal changes. Eye 2008;22: 1214–1222. 2. COULOMBRE AJ. The role of intraocular pressure in the development of the chick eye. I. Control of eye size. J. Exper. Zool 1956;133:211–225.3. Los LI, van der Worp RJ, van Luyn MJ, Hooymans JM. Age-related liquefaction of the human vitreous body: LM and TEM evaluation of the role of proteoglycans and collagen. Invest Ophthalmol Vis Sci 2003;44:2828–2833.4. Foos RY, Wheeler NC. Vitreoretinal juncture: synchysis senilis and posterior vitreous detachment. Ophthalmology 1982;89:1502–1512.5. Foos RY. Posterior vitreous detachment. Trans Am Acad Ophthalmol Otolaryngol 1972;76:480–496.6. Eisner G. [Postmortem slitlamp study of the vitreous body. 3. Relation to histology, biomicroscopy and clinical applications]. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1971;182:23-40.7. Deike-Hofmann K, Kuder T, König F, Paech D, Dreher C, Delorme S, et al. Diffusion-weighted breast imaging. Radiologe. 2018;58:14-19. 8. de Figueiredo EH, Borgonovi AF, Doring TM. Basic concepts of MR imaging, diffusion MR imaging and diffusion tensor imaging. Magn Reson Imaging Clin N Am 2011;19:1-22.9. Zhu ZR, Goodnight R, Sorgente N, Ogden TE, Ryan SJ. Morphologic observations of retinal pigment epithelial proliferation and neovascularization in the rabbit. Retina 1989;9:319-327.10. Itakura H, Kishi S, Kotajima N, Murakami M. Decreased vitreal hyaluronan levels with agingi Ophthalmologica 2009;223:32–3511. Bishop PN. Structural macromolecules and supramolecular organisation of the vitreous gel. Prog Retin Eye Res 2000;19:323–344.12. Böhm MRR, Thomasen H, Parnitzke F, Steuhl KP. [Clinical, morphological and molecular biological characteristics of the aging eye]. Ophthalmologe 2017;114:98-107.13. Eisner G. Postmortem slitlamp study of the vitreous body. II. Pattern of vitreous structures made visible by the slitbeam. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1971;182:8–2214. Sebag J. Age-related changes in human vitreous structure. Graefes Arch Clin Exp Ophthalmol 1987;225:89–9315. Basser PJ, Mattiello J, Le Bihan D. Estimation of the effective self diffusion tensor from the NMR spin echo. J Magn Reson B 1994;103:247–254.16. Seiko Kuroki-Suzuki, Yoshifumi Kuroki, Katsuhiro Nasu, Shigeru Nawano, Noriyuki Moriyama, Masatoshi Okazaki. Detecting Breast Cancer with Non-contrast MR Imaging: Combining Diffusion-weighted and STIR Imaging. Magn Reson Med Sci 2007;6:21-27.17. Lövblad KO, Delavelle J, Wetzel S, Kelekis AD, Assal F, Palmesino M, et al. ADC mapping of the aging frontal lobes in mild cognitive impairment. Neuroradiology 2004;46:282-286.18. Engelter ST, Provenzale JM, Petrella JR, DeLong DM, MacFall JR. The effect of aging on the apparent diffusion coefficient of normal-appearing white matter. AJR Am J Roentgenol 2000;175:425-43019. Meral I, Bilgili Y. Diffusion changes in the vitreous humor of the eye during aging. AJNR Am J Neuroradiol 2011;32:1563-6.20. Sebag J. The vitreous. In: Adler FH, Hart WM, eds. Adler’s physiology of the eye. 9th ed. St. Louis: Mosby 1992:268-347.21. Shui YB, Holekamp NM, Kramer BC, Crowley JR, Wilkins MA, Chu F, et al. The gel state of the vitreous and ascorbate-dependent oxygen consumption: relationship to the etiology of nuclear cataract. Arch Ophthalmol 2009;127:475-482.22. Chang S. LXII Edward Jackson lecture: open angle glaucoma after vitrectomy. Am J Ophthalmol 2006;141:1033-1043.23. Sebag J. Anomalous posterior vitreous detachment: a unifying concept in vitreo-retinal disease Graefes Arch Clin Exp Ophthalmol. 2004;242:690-698.

Yaşlanma ile İlişkili Vitreus Humor Değişikliklerinin Difüzyon MRG ile Değerlendirilmesi

Year 2019, , 266 - 271, 28.06.2019
https://doi.org/10.31832/smj.532943

Abstract

ÖZ



Amaç Bu çalışmada, vitreus
humorde yaşlanma ile ilişkili DAG ile belirlemeyi amaçladık.



Gereç ve Yöntem
Ekim 2018 ile Ocak 2019 tarihleri arasında, veri tabanımızda anahtar kelime
arama özelliği ile beyin difüzyon MRG tetkiki uygulanan hastalar retrospektif
olarak tarandı ve vitreus kanaması, glokom, kontrolsüz hipertansiyon veya
diabetes mellitusu olan hastalar çalışma dışında bırakıldı. Sonuçta, 211 hasta
çalışmaya dahil edildi ve hastalar yaşlarına göre dekadlara ayrıldı. Olguların
yaşları ile vitreus humor ADC değerleri arasında regresyon analizi yapıldı.



Bulgular Çalışmaya
dahil edilen 211 hastanın (102 kadın, 109 erkek) yaşlarının ortalaması 53,8 (±
21,4) yıl olup en az 3 yıl ve en fazla 89 yıldır. Vitreus humor ADC değerleri
artan yaş ile birlikte lineer artış gösterdi ve istatistiksel olarak anlamlı
pozitif korelasyon saptandı (p<0,001). Dekadlar arasındaki vitreus humor ADC
değerleri karşılaştırıldığında ilk üç dekad arasında anlamlı fark saptanmazken
(p>0.005) diğer dekadlar arasında istatiksel anlamlı fark saptandı (p<0,005).



Sonuç Vitreus humorde
yaşlanmayla ile ilşkili yapısal değişikliklerin anlaşılması daha etkili tedavi
geliştirmek için önemlidir. Çalışmamızın sonuçlarına göre, vitreus humor ADC
değerleri ilk üç dekadda anlamlı fark göstermemekle beraber yaşla beraber
pozitif korelasyon gösterdi. 

References

  • 1. Le Goff MM, Bishop PN. Adult vitreous structure and postnatal changes. Eye 2008;22: 1214–1222. 2. COULOMBRE AJ. The role of intraocular pressure in the development of the chick eye. I. Control of eye size. J. Exper. Zool 1956;133:211–225.3. Los LI, van der Worp RJ, van Luyn MJ, Hooymans JM. Age-related liquefaction of the human vitreous body: LM and TEM evaluation of the role of proteoglycans and collagen. Invest Ophthalmol Vis Sci 2003;44:2828–2833.4. Foos RY, Wheeler NC. Vitreoretinal juncture: synchysis senilis and posterior vitreous detachment. Ophthalmology 1982;89:1502–1512.5. Foos RY. Posterior vitreous detachment. Trans Am Acad Ophthalmol Otolaryngol 1972;76:480–496.6. Eisner G. [Postmortem slitlamp study of the vitreous body. 3. Relation to histology, biomicroscopy and clinical applications]. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1971;182:23-40.7. Deike-Hofmann K, Kuder T, König F, Paech D, Dreher C, Delorme S, et al. Diffusion-weighted breast imaging. Radiologe. 2018;58:14-19. 8. de Figueiredo EH, Borgonovi AF, Doring TM. Basic concepts of MR imaging, diffusion MR imaging and diffusion tensor imaging. Magn Reson Imaging Clin N Am 2011;19:1-22.9. Zhu ZR, Goodnight R, Sorgente N, Ogden TE, Ryan SJ. Morphologic observations of retinal pigment epithelial proliferation and neovascularization in the rabbit. Retina 1989;9:319-327.10. Itakura H, Kishi S, Kotajima N, Murakami M. Decreased vitreal hyaluronan levels with agingi Ophthalmologica 2009;223:32–3511. Bishop PN. Structural macromolecules and supramolecular organisation of the vitreous gel. Prog Retin Eye Res 2000;19:323–344.12. Böhm MRR, Thomasen H, Parnitzke F, Steuhl KP. [Clinical, morphological and molecular biological characteristics of the aging eye]. Ophthalmologe 2017;114:98-107.13. Eisner G. Postmortem slitlamp study of the vitreous body. II. Pattern of vitreous structures made visible by the slitbeam. Albrecht Von Graefes Arch Klin Exp Ophthalmol 1971;182:8–2214. Sebag J. Age-related changes in human vitreous structure. Graefes Arch Clin Exp Ophthalmol 1987;225:89–9315. Basser PJ, Mattiello J, Le Bihan D. Estimation of the effective self diffusion tensor from the NMR spin echo. J Magn Reson B 1994;103:247–254.16. Seiko Kuroki-Suzuki, Yoshifumi Kuroki, Katsuhiro Nasu, Shigeru Nawano, Noriyuki Moriyama, Masatoshi Okazaki. Detecting Breast Cancer with Non-contrast MR Imaging: Combining Diffusion-weighted and STIR Imaging. Magn Reson Med Sci 2007;6:21-27.17. Lövblad KO, Delavelle J, Wetzel S, Kelekis AD, Assal F, Palmesino M, et al. ADC mapping of the aging frontal lobes in mild cognitive impairment. Neuroradiology 2004;46:282-286.18. Engelter ST, Provenzale JM, Petrella JR, DeLong DM, MacFall JR. The effect of aging on the apparent diffusion coefficient of normal-appearing white matter. AJR Am J Roentgenol 2000;175:425-43019. Meral I, Bilgili Y. Diffusion changes in the vitreous humor of the eye during aging. AJNR Am J Neuroradiol 2011;32:1563-6.20. Sebag J. The vitreous. In: Adler FH, Hart WM, eds. Adler’s physiology of the eye. 9th ed. St. Louis: Mosby 1992:268-347.21. Shui YB, Holekamp NM, Kramer BC, Crowley JR, Wilkins MA, Chu F, et al. The gel state of the vitreous and ascorbate-dependent oxygen consumption: relationship to the etiology of nuclear cataract. Arch Ophthalmol 2009;127:475-482.22. Chang S. LXII Edward Jackson lecture: open angle glaucoma after vitrectomy. Am J Ophthalmol 2006;141:1033-1043.23. Sebag J. Anomalous posterior vitreous detachment: a unifying concept in vitreo-retinal disease Graefes Arch Clin Exp Ophthalmol. 2004;242:690-698.
There are 1 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Articles
Authors

Ali Küpeli 0000-0002-5322-2972

Mehmet Koçak This is me 0000-0003-3590-0327

Gürkan Danışan 0000-0003-2052-0006

Mehmet Soytürk This is me 0000-0002-9011-3660

Publication Date June 28, 2019
Submission Date February 26, 2019
Published in Issue Year 2019

Cite

AMA Küpeli A, Koçak M, Danışan G, Soytürk M. Yaşlanma ile İlişkili Vitreus Humor Değişikliklerinin Difüzyon MRG ile Değerlendirilmesi. Sakarya Tıp Dergisi. June 2019;9(2):266-271. doi:10.31832/smj.532943

30703

SMJ'de yayınlanan makaleler, Creative Commons Atıf-GayriTicari 4.0 Uluslararası Lisansı kapsamında lisanslanır