Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi?

Aysegul Ugural; Aylin Ayaz

doi:10.31832/smj.583473

Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi?

Abstract

K vitamini yağda çözünen bir vitamin olup doğada filokinon (K1) ve menakinon (K2) formlarında bulunmaktadır. Menadion (K3) formu ise sentetik analog olarak kullanılmaktadır. K vitamini, metabolizmada K vitaminine bağımlı proteinlerin karboksilasyonundan sorumludur. Genellikle kan koagülasyonü üzerine rolü olduğu bilinen K vitamininin günümüzde kardiyovasküler hastalıklar, osteoporoz, vasküler kalsifikasyon, kanser, diyabet ve glisemik kontrol ile de ilişkisi olduğu gösterilmiştir. Son yıllarda ise beyinde miyelinizasyonun yoğun olduğu bölgelerde Menakinon-4 (MK-4) formunda bulunduğu saptanmış ve bilişsel performans ile bazı nörodejeneratif hastalıkların patogenezinde rol alabileceği belirtilmiştir. Bu etkisini Gas-6 ve protein S gibi proteinler aracılığıyla veya nöronları oksidatif stres hasarına karşı koruyarak gösterdiği düşünülmektedir. Atriyal fibrilasyon (AF) hastalarının sıklıkla kullandığı antikoagülanların ve K vitamini antagonisti olmayan antikoagülanların bilişsel performans ve demans üzerine etkisi ise tartışmalıdır. Bu derleme makalede K vitamini ve antikoagülanların bilişsel performans üzerine etkileri ele alınmıştır.

Keywords

K vitamini,bilişsel performans,Alzheimer,antikoagülanlar

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Details

Primary Language

Turkish

Subjects

Health Care Administration

Journal Section

Review

Authors

Aysegul Ugural ^*
0000-0003-0097-1096
Türkiye

Aylin Ayaz
0000-0002-3543-7881
Türkiye

Publication Date

March 16, 2020

Submission Date

June 27, 2019

Acceptance Date

December 26, 2019

Published in Issue

Year 2020 Volume: 10 Number: 1

DOI

https://doi.org/10.31832/smj.583473

IZ

https://izlik.org/JA47TY63LH

Cite

RIS / Bibtex

APA

Ugural, A., & Ayaz, A. (2020). Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi? Sakarya Medical Journal, 10(1), 162-170. https://doi.org/10.31832/smj.583473

AMA

1.Ugural A, Ayaz A. Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi? Sakarya Medical Journal. 2020;10(1):162-170. doi:10.31832/smj.583473

Chicago

Ugural, Aysegul, and Aylin Ayaz. 2020. “Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler Mi?”. Sakarya Medical Journal 10 (1): 162-70. https://doi.org/10.31832/smj.583473.

EndNote

Ugural A, Ayaz A (March 1, 2020) Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi? Sakarya Medical Journal 10 1 162–170.

IEEE

[1]A. Ugural and A. Ayaz, “Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi?”, Sakarya Medical Journal, vol. 10, no. 1, pp. 162–170, Mar. 2020, doi: 10.31832/smj.583473.

ISNAD

Ugural, Aysegul - Ayaz, Aylin. “Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler Mi?”. Sakarya Medical Journal 10/1 (March 1, 2020): 162-170. https://doi.org/10.31832/smj.583473.

JAMA

1.Ugural A, Ayaz A. Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi? Sakarya Medical Journal. 2020;10:162–170.

MLA

Ugural, Aysegul, and Aylin Ayaz. “Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler Mi?”. Sakarya Medical Journal, vol. 10, no. 1, Mar. 2020, pp. 162-70, doi:10.31832/smj.583473.

Vancouver

1.Aysegul Ugural, Aylin Ayaz. Diyetle K Vitamini Alımı Bilişsel Performansı Etkiler mi? Sakarya Medical Journal. 2020 Mar. 1;10(1):162-70. doi:10.31832/smj.583473