A promising marker for carotid artery disease: Monocyte to high-density lipoprotein ratio (MHR)

Year 2020, , 93 - 98, 16.03.2020

Mehmet Kirişçi

https://doi.org/10.31832/smj.644699

Abstract

Objectives: The aim of our study
was to evaluate the relation between monocyte/high-density lipoprotein(HDL)
ratio value and carotid artery stenosis in patients who underwent carotid
angiography.

Methods: To our study, 94
participants were enrolled (68 patients, 26 healthy individuals) who attended
the cardiovascular surgery policlinic and had carotid angiography in between
January 2017 and June 2018. Participants were divided into two groups, who have
carotid artery disease and who don't. Peripheral venous blood results, taken
from all patients before angiography for hematologic examination, were
evaluated. Groups were compared according to their monocyte/high-density
lipoprotein(HDL)  values and other
hematologic results.

Results: Monocyte/high-density
lipoprotein(HDL) ratio values were found to be higher in the group with a
carotid artery disease compared to the group with a normal carotid angiography
(72±10 ver 68±11  p=0.063). Yet again
when the two groups were compared, there were differences with respect to
existing hypertension, existing diabetes and gender (p=0.034, p=0.043, p=0.035
respectively).

Conclusion: In our study, it was
shown that high monocyte/high-density lipoprotein(HDL) ratio value can be a
predictor for the diagnosis of carotid artery disease.

Keywords

Carotid artery disease, Atherosclerosis risk factors, Monocyte/high-density lipoprotein(HDL) ratio

Karotis Arter Hastalığı İçin Ümit Verici Bir Marker: Monositin High Density Lipoproteine Oranı (MHR)

Abstract

Giriş:
Çalışmamızın amacı karotis arter angiografisi yapılan hastalarda MHR
(monosit/HDL ratio) değerlerinin karotis arter stenozu ile ilişkisini
retrospektif olarak araştırmaktı.

Gereç ve Yöntemler:
Çalışmamıza ocak 2017 ile haziran 2018 yılları arasında kardiyoloji ve kalp ve
damar cerrahisi polikliniğine başvuran karotis arter angiografisi yapılan 94
(68 hasta, 26 sağlıklı) hasta dahil edildi. Karotis arter hastalığı olanlar ve
olmayanlar diye iki gruba ayrıldı. Tüm hastaların hematolojik değerlerine
bakılması için angiografi öncesi alınan periferik venöz kan sonuçları tarandı.
Gruplar MHR değeri ve diğer hematolojik sonuçlar açısından karşılaştırıldı.

Bulgular:
MHR değeri karotis arter hastalığı olanlar grubunda karotis arter angiografisi
normal çıkan gruba göre anlamlı olarak yüksek bulundu (68±11 ver 721±10,
p=0.063). Yine iki grup kıyaslandığında hipertansiyon, diabetus mellitus
varlığı ve cinsiyet açısından gruplar arasında farklılk vardı (
p=0,034,p=0,043,p=0,035,sırası ile).

Sonuç:
Çalışmamızda yüksek MHR değerinin karotis arter hastalığı tanısında bir öngördürücü
olabileceği gösterildi.

Keywords

Karotis arter hastalığı, Monosit/HDL oranı(MHR), Aterosklerotik risk faktörleri

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