Abstract
Familial adenomatous polyposis coli (FAP) is an inherited syndrome in which numerous polyps form mainly in colonic epithelium. Risk for cancer development gradually increases in such a condition if left untreated. Due to apparent symptoms such as rectal bleeding and abdominal pain, patients usually diagnosed at an early age. We report a FAP case with malignant transformation which is diagnosed at emergency department.
Keywords
References
- Büyükdoğan M. Kolorektal kanserde genetik ve etyolojik faktörler. Selçuk Tıp Derg 2009; 25 (3): 171-180.
- Nandakumar G, Morgan JA, Silverberg D, Steinhagen RM. Familial polyposis coli: clinical manifestations, evaluation, management and treatment. Mt Sinai J Med 2004; 71: 384-91.
- Cruz-Correa M, Giardiello FM. Diagnosis and management of hereditary colon cancer. Gastroenterol Clin North Am 2002; 31: 537-49.
- Contessini-Avesani E, Botti F, Negri C. Familial adenomatous polyposis. Surgical treatment: when and how. Tech Coloproctol 2004; 8: 309-14.
- Fotiadis C, Tsekouras DK, Antonakis P, et al. Gardner’s syndrome: A case report and rewiev of the literature. World Gastroenterol 2005; 11: 5408- 11.
- Kartheuser A, Stangherlin P, Brandt D, et al. Restorative proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis revisited. Familial Cancer 2006; 5: 241-60.
- Ishikawa H. Chemoprevention of carcinogenesis in familial tumors. Int J Clin Oncol 2004; 9: 299-303.
- Giardiello FM, Yang VWW, Hylind LM. Primary chemoprevention of familial adenomatous polyposis with sulindac. N Eng J Med 2002; 346: 1054-9.
Abstract
Familyal adenomatöz polipozi koli (FAP) özellikle kolon epitelinde çok sayıda polip oluşumuyla karakterize genetik geçişli bir sendromdur. Tedavi edilmediği takdirde kanser gelişme riski giderek artmaktadır. Rektal kanama ve karın ağrısı gibi aşikar semptomlardan dolayı hastalar genellikle erken tanı almaktadır. Biz burada acil serviste tanı konulmuş olan malign transformasyon göstermiş bir FAP olgusunu sunmaktayız.
Keywords
References
- Büyükdoğan M. Kolorektal kanserde genetik ve etyolojik faktörler. Selçuk Tıp Derg 2009; 25 (3): 171-180.
- Nandakumar G, Morgan JA, Silverberg D, Steinhagen RM. Familial polyposis coli: clinical manifestations, evaluation, management and treatment. Mt Sinai J Med 2004; 71: 384-91.
- Cruz-Correa M, Giardiello FM. Diagnosis and management of hereditary colon cancer. Gastroenterol Clin North Am 2002; 31: 537-49.
- Contessini-Avesani E, Botti F, Negri C. Familial adenomatous polyposis. Surgical treatment: when and how. Tech Coloproctol 2004; 8: 309-14.
- Fotiadis C, Tsekouras DK, Antonakis P, et al. Gardner’s syndrome: A case report and rewiev of the literature. World Gastroenterol 2005; 11: 5408- 11.
- Kartheuser A, Stangherlin P, Brandt D, et al. Restorative proctocolectomy and ileal pouch-anal anastomosis for familial adenomatous polyposis revisited. Familial Cancer 2006; 5: 241-60.
- Ishikawa H. Chemoprevention of carcinogenesis in familial tumors. Int J Clin Oncol 2004; 9: 299-303.
- Giardiello FM, Yang VWW, Hylind LM. Primary chemoprevention of familial adenomatous polyposis with sulindac. N Eng J Med 2002; 346: 1054-9.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | December 1, 2014 |
| Submission Date | September 7, 2015 |
| Published in Issue | Year 2014 Volume: 4 Issue: 4 |
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