BibTex RIS Cite

Lipid peroxidation and antioxidant enzymes

Year 2013, Volume: 3 Issue: 1, 5 - 7, 01.03.2013
https://doi.org/10.5505/sakaryamj.2013.87609

Abstract

The role of reactive oxygen species (ROS) in the pathologic and physiologic effects on health has been emphasized in recent years. Production of ROS by mitochondria is generally thought to be the main cause of oxidative stres (OS). ROS are neutralized by various antioxidant defense mechanisms such as catalase, superoxide dismutase and glutathione peroxidase, vitamin C, vitamin E, vitamin A, pyruvate, glutathione, taurine and hypotaurine. Biomarkers of oxidative damage associated with human diseases could be used to diagnose and manage the diseases.

References

  • Sangameswaran B Balakrıshnan Br, Chumbhale Deshraj And Jayakar B. In Vıtro Antıoxıdant Actıvıty Of Roots Of Thespesıa Lampas Dalz And Gıbs. Pak. J. Pharm. Sci. 2009;22:4;368-372
  • Cross CE, Halliwell B, Borish ET, Pryor WA, Ames BN, Saul RL et al. Oxygen radicals and human disease. Ann Intern Med. 1987;107(4):526-45.
  • Ho YS, Magnenat JL, Gargano M, Cao J. The nature of antioxidant defense mechanisms: a lesson from transgenic studies. Environ Health Perspect. 1998;106:5:1219-28.
  • Mohsenzadegan M, Mirshafiey A. The immunopathogenic role of reactive oxygen species in Alzheimer disease. . Iran J Allergy Asthma Immunol. 2012;11(3):203-16.
  • Sorce S, Krause KH. NOX enzymes in the central nervous system: from signaling to disease. Antioxid Redox Signal. 2009;11(10):2481-504.
  • Gümüştaş K, Atukeren P. Oksidatif ve nitrozatif stresin psikiyatrik bozukluklar ile ilişkisi. İÜCerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri. Türkiye’de sık karşılaşılan psikiyatrik hastalıklar. Sempozyum Dizisi 2008;62;329-340.
  • Yoshida Y, Umeno A, Shichiri M. Lipid peroxidation biomarkers for evaluating oxidative stress and assessing antioxidant capacity in vivo. J Clin Biochem Nutr. 2013;52(1):9-16.
  • Vetrani C, Costabile G, Di Marino L, Rivellese AA. Nutrition and oxidative stress: a systematic review of human studies. nt J Food Sci Nutr. 2012.
  • D. Harman. Aging—A theory based on free-radical and radiation- chemistry J. Gerontol.1956;11:298–300
  • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 2007;39(1):44-84.
  • Michel F, Bonnefont-Rousselot D, Mas E, Drai J, Thérond P. Biomarkers of lipid peroxidation: analytical aspects. Ann Biol Clin (Paris). 2008;66(6):605-20.
  • Blumberg J. Use of Biomarkers of Oxidative Stress in Research Studies. American Society for Nutritional Sciences. J. Nutr. 2004;134: 3188S–3189S,

Lipid peroksidasyonu ve antioksidan enzimler

Year 2013, Volume: 3 Issue: 1, 5 - 7, 01.03.2013
https://doi.org/10.5505/sakaryamj.2013.87609

Abstract

Reaktif oksijen türlerinin (ROS) sağlık üzerindeki patolojik ve fizyolojik etkileri son yıllarda vurgulanmaktadır. Mitokondri tarafından ROS üretiminde oksidatif stresin ana neden olduğu genellikle düşünülmektedir. ROS katalaz, superoksid dismutaz, glutatyon peroksidaz, vitamin C, Vitamin E, vitamin A, pruvat, glutatyon, taurin, hiptaurin gibi antioksidan savunma mekanizmaları tarafından nötralize edilmektedir. Hastalıklarla ilişkili olan oksidatif hasar biyobelirteçleri hastalıkların teşhis ve idaresinde kullanılmaktadır.

References

  • Sangameswaran B Balakrıshnan Br, Chumbhale Deshraj And Jayakar B. In Vıtro Antıoxıdant Actıvıty Of Roots Of Thespesıa Lampas Dalz And Gıbs. Pak. J. Pharm. Sci. 2009;22:4;368-372
  • Cross CE, Halliwell B, Borish ET, Pryor WA, Ames BN, Saul RL et al. Oxygen radicals and human disease. Ann Intern Med. 1987;107(4):526-45.
  • Ho YS, Magnenat JL, Gargano M, Cao J. The nature of antioxidant defense mechanisms: a lesson from transgenic studies. Environ Health Perspect. 1998;106:5:1219-28.
  • Mohsenzadegan M, Mirshafiey A. The immunopathogenic role of reactive oxygen species in Alzheimer disease. . Iran J Allergy Asthma Immunol. 2012;11(3):203-16.
  • Sorce S, Krause KH. NOX enzymes in the central nervous system: from signaling to disease. Antioxid Redox Signal. 2009;11(10):2481-504.
  • Gümüştaş K, Atukeren P. Oksidatif ve nitrozatif stresin psikiyatrik bozukluklar ile ilişkisi. İÜCerrahpaşa Tıp Fakültesi Sürekli Tıp Eğitimi Etkinlikleri. Türkiye’de sık karşılaşılan psikiyatrik hastalıklar. Sempozyum Dizisi 2008;62;329-340.
  • Yoshida Y, Umeno A, Shichiri M. Lipid peroxidation biomarkers for evaluating oxidative stress and assessing antioxidant capacity in vivo. J Clin Biochem Nutr. 2013;52(1):9-16.
  • Vetrani C, Costabile G, Di Marino L, Rivellese AA. Nutrition and oxidative stress: a systematic review of human studies. nt J Food Sci Nutr. 2012.
  • D. Harman. Aging—A theory based on free-radical and radiation- chemistry J. Gerontol.1956;11:298–300
  • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol. 2007;39(1):44-84.
  • Michel F, Bonnefont-Rousselot D, Mas E, Drai J, Thérond P. Biomarkers of lipid peroxidation: analytical aspects. Ann Biol Clin (Paris). 2008;66(6):605-20.
  • Blumberg J. Use of Biomarkers of Oxidative Stress in Research Studies. American Society for Nutritional Sciences. J. Nutr. 2004;134: 3188S–3189S,
There are 12 citations in total.

Details

Primary Language Turkish
Journal Section Articles
Authors

Gönül Gürol This is me

Ali Aslan This is me

Publication Date March 1, 2013
Submission Date September 7, 2015
Published in Issue Year 2013 Volume: 3 Issue: 1

Cite

AMA Gürol G, Aslan A. Lipid peroksidasyonu ve antioksidan enzimler. Sakarya Tıp Dergisi. March 2013;3(1):5-7. doi:10.5505/sakaryamj.2013.87609

30703

The published articles in SMJ are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.