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Obstrüktif Uyku Apne Sendromu Olan Hastalarda Klinik ve Demografik Verilerinin Değerlendirilmesi

Year 2021, Volume: 11 Issue: 1, 103 - 108, 22.03.2021
https://doi.org/10.31832/smj.768573

Abstract

ÖZET:
Amaç: Çalışmanın amacı horlama şikayeti ile başvuran hastalarda obstrüktif uyku apne sendromu (OUAS) varlığının değerlendirilmesi ve OUAS’lı hastaların demografik verilerini ve eşlik eden kronik hastalık birlikteliğini araştırmaktır.
Gereç ve Yöntemler: Bu çalışmada Ocak 2017- Haziran 2018 tarihleri arasında, uykuda horlama ve apne şikayetleriyle İstanbul Eğitim ve Araştırma Hastanesi uyku laboratuvarına yönlendirilen hastalar incelendi. Hastaların anamnezleri alınarak horlama ve/veya apne şikayetlerinin yanı sıra kronik rahatsızlıklarının olup olmadığı sorgulanmış, alışkanlıkları ve demografik verileri kaydedilmiştir. Hastalarda OUAS varlığının tespiti için 1 gece süreyle polisomnografi testi yapılmış ve Apne Hipopne İndeksine (AHİ) göre hastalar gruplandırılmıştır. AHİ ≥ 5 olması OUAS olarak kabul edilmiş, AHİ 5.0-14.9 arası hafif, 15.0-29.9 arası orta, 30.0 ve üzeri ağır olarak gruplandırılmıştır. Hastaların ayrıca periyodik bacak hareket İndeksi (PBHİ) değerlendirilmiştir.
Bulgular: Polisomnografi test sonuçlarına göre hastaların 100'ü basit horlama (%26), 103'ü (%26.7) hafif derecede OUAS, 84'ü (%21.8) orta derecede OUAS ve 98'i (%25.4) ağır derecede OUAS olarak değerlendirilmiştir. Yaş, Beden Kitle İndeksi (VKİ) ve hipertansiyon varlığı OUAS’lı grupta daha yüksek olarak saptanmıştır.
Sonuç: OUAS hastalarında; erkek cinsiyetin hakim olduğu, bu hastaların daha yaşlı olduğu, hipertansiyonun eşlik ettiği ve vücut kitle indekslerinin (VKİ) daha yüksek olduğu bulunmuştur.

References

  • 1. Coleman JA. Pathophyology of snoring and sleep apnea: airway dynamics. In Snoring and Obsturictive Sleep Apnea. Ed. Fairbanks D, Mickelson S, Woodson T. Lippincot Williams & Wilkins .Philadelphia 2003. Chapter 2:19-25. 3rd edition
  • 2. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005;365:1046-53.
  • 3. Köktürk O, Köktürk N. Obstrüktif uyku apne sendromu fizyopotolojisi. Tüberküloz ve Toraks 1998; 46: 288-300.
  • 4. Papilla İ, Acıoğlu E. Obstrüktif Uyku Apne Sendromu. Klinik Gelişim 2005; 18: 42-50.
  • 5. Köktürk O. Obstrüktif uyku apne sendromu epidemiyolojisi. Tüberküloz ve Toraks 1998; 46: 193-201
  • 6.McNamara SG, Grunstein RR, Sullivan CE. Obstructive sleep apnea. Thorax 1993; 48: 754-63
  • 7.Nieto FJ, Young TB, Lind BK, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in large community based study. JAMA 2000; 283: 1829-36
  • 8. Wittels E, Thompson S. Obstructive sleep apnea and obesity. Otolaryngol Clin North Am 1990; 23; 751-60
  • 9. Schwab RJ. Upper airway imaging. Clinics in chest medicine. 1998;19(1):33-54.
  • 10. Stauffer JL, Buick MK, Bixler EO, Sharkey FE, Abt AB, Manders EK, et al. Morphology of the Uvula in Obstructive Sleep Apnea1-3. The American review of respiratory disease. 1989;140:724.
  • 11. Zohar Y, Schwartz A, Sabo R, Gal R, Strauss M, Oksenberg A. Oropharyngeal fatty infltration in obstructive sleep apnea patients: a histologic study. Annals of Otology, Rhinology & Laryngology. 1998;107(2):170-4.
  • 12. Nashi N, Kang S, Barkdull GC, Lucas J, Davidson TM. Lingual fat at autopsy. The Laryngoscope. 2007;117(8):1467-73.
  • 13 . Fletcher EC, De Behnke RD, Lovoi MS, Gorin AB. Undiagnosed sleep apnea in patients with essential hypertension. Ann Intern Med. 1985;103(2):190-5.
  • 14 . Sharabi Y, Dagan Y, Grossman E. Sleep apnea as a risk factor for hypertension. Curr Opin Nephrol Hypertens. 2004;13(3):359-64..
  • 15. Al-Delaimy WK, Manson JE, Willlett WC, Stampfer MJ, Hu FB. Snoring as a risk factor for type II diabetes mellitus: a prospective study. Am J Epidemiol. 2002;155(5):387-93.
  • 16.. Meslier N, Gagnadoux F, Giraud P, Person C, Ouksel H, Urban T, Racineux JL. Impaired glucose-insulin metabolism in males with obstructive sleep apnoea syndrome. Eur Respir J. 2003;22(1):156-60.
  • 17. Guilleminault C. Clinical features and evaluation of obstructive sleep apnea. In: Kryger MH, Roth T, Dement WC (Eds). Principles and Practice of Sleep Medicine. Philadelphia : W.B. Saunders Company, 1994; 667-677.
  • 18.Al-Alawi A, Mulgrew A, Tench E, Ryan CF. Prevalence, risk factors and impact on daytime sleepiness and hypertension of periodic leg movements with arousals in patients with obstructive sleep apnea. J Clin Sleep Med 2006;15:2:281-287.
  • 19. Manconi M, Zavalko I, Bassetti CL, Colamartino E, Pons M, Ferri R. Respiratory-related leg movements and their relationship with periodic leg movements during sleep. Sleep 2014;37:494-504.
Year 2021, Volume: 11 Issue: 1, 103 - 108, 22.03.2021
https://doi.org/10.31832/smj.768573

Abstract

References

  • 1. Coleman JA. Pathophyology of snoring and sleep apnea: airway dynamics. In Snoring and Obsturictive Sleep Apnea. Ed. Fairbanks D, Mickelson S, Woodson T. Lippincot Williams & Wilkins .Philadelphia 2003. Chapter 2:19-25. 3rd edition
  • 2. Marin JM, Carrizo SJ, Vicente E, Agusti AG. Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005;365:1046-53.
  • 3. Köktürk O, Köktürk N. Obstrüktif uyku apne sendromu fizyopotolojisi. Tüberküloz ve Toraks 1998; 46: 288-300.
  • 4. Papilla İ, Acıoğlu E. Obstrüktif Uyku Apne Sendromu. Klinik Gelişim 2005; 18: 42-50.
  • 5. Köktürk O. Obstrüktif uyku apne sendromu epidemiyolojisi. Tüberküloz ve Toraks 1998; 46: 193-201
  • 6.McNamara SG, Grunstein RR, Sullivan CE. Obstructive sleep apnea. Thorax 1993; 48: 754-63
  • 7.Nieto FJ, Young TB, Lind BK, et al. Association of sleep-disordered breathing, sleep apnea, and hypertension in large community based study. JAMA 2000; 283: 1829-36
  • 8. Wittels E, Thompson S. Obstructive sleep apnea and obesity. Otolaryngol Clin North Am 1990; 23; 751-60
  • 9. Schwab RJ. Upper airway imaging. Clinics in chest medicine. 1998;19(1):33-54.
  • 10. Stauffer JL, Buick MK, Bixler EO, Sharkey FE, Abt AB, Manders EK, et al. Morphology of the Uvula in Obstructive Sleep Apnea1-3. The American review of respiratory disease. 1989;140:724.
  • 11. Zohar Y, Schwartz A, Sabo R, Gal R, Strauss M, Oksenberg A. Oropharyngeal fatty infltration in obstructive sleep apnea patients: a histologic study. Annals of Otology, Rhinology & Laryngology. 1998;107(2):170-4.
  • 12. Nashi N, Kang S, Barkdull GC, Lucas J, Davidson TM. Lingual fat at autopsy. The Laryngoscope. 2007;117(8):1467-73.
  • 13 . Fletcher EC, De Behnke RD, Lovoi MS, Gorin AB. Undiagnosed sleep apnea in patients with essential hypertension. Ann Intern Med. 1985;103(2):190-5.
  • 14 . Sharabi Y, Dagan Y, Grossman E. Sleep apnea as a risk factor for hypertension. Curr Opin Nephrol Hypertens. 2004;13(3):359-64..
  • 15. Al-Delaimy WK, Manson JE, Willlett WC, Stampfer MJ, Hu FB. Snoring as a risk factor for type II diabetes mellitus: a prospective study. Am J Epidemiol. 2002;155(5):387-93.
  • 16.. Meslier N, Gagnadoux F, Giraud P, Person C, Ouksel H, Urban T, Racineux JL. Impaired glucose-insulin metabolism in males with obstructive sleep apnoea syndrome. Eur Respir J. 2003;22(1):156-60.
  • 17. Guilleminault C. Clinical features and evaluation of obstructive sleep apnea. In: Kryger MH, Roth T, Dement WC (Eds). Principles and Practice of Sleep Medicine. Philadelphia : W.B. Saunders Company, 1994; 667-677.
  • 18.Al-Alawi A, Mulgrew A, Tench E, Ryan CF. Prevalence, risk factors and impact on daytime sleepiness and hypertension of periodic leg movements with arousals in patients with obstructive sleep apnea. J Clin Sleep Med 2006;15:2:281-287.
  • 19. Manconi M, Zavalko I, Bassetti CL, Colamartino E, Pons M, Ferri R. Respiratory-related leg movements and their relationship with periodic leg movements during sleep. Sleep 2014;37:494-504.
There are 19 citations in total.

Details

Primary Language Turkish
Subjects Health Care Administration
Journal Section Articles
Authors

Ahmet Yıldırım 0000-0002-6644-9148

Aysel Kaya Tekeşin 0000-0002-0856-9387

Publication Date March 22, 2021
Submission Date July 13, 2020
Published in Issue Year 2021 Volume: 11 Issue: 1

Cite

AMA Yıldırım A, Kaya Tekeşin A. Obstrüktif Uyku Apne Sendromu Olan Hastalarda Klinik ve Demografik Verilerinin Değerlendirilmesi. Sakarya Tıp Dergisi. March 2021;11(1):103-108. doi:10.31832/smj.768573

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