Varfarin veya Yeni Nesil Oral Antikoagülan Kullanan Atriyal Fibrilasyonlu Hastalarda Tedavi Maliyetinin Analiz Çalışması

Year 2021, Volume: 11 Issue: 2, 322 - 327, 29.06.2021

Ercan Aydın , Aydın Kant , Altuğ Ösken , Salih Şahinkuş , Selcuk Yaylacı

https://doi.org/10.31832/smj.844292

Abstract

Amaç: Atriyal fibrilasyonu olan hastalarda varfarin ve yeni nesil oral antikoagülan (NOAC) tedavisinin maliyet analizini karşılaştırdık.
Gereç ve Yöntemler: Kardiyoloji polikliniğinden atriyal fibrilasyon tanısı alan, varfarin veya NOAC tedavisi kullanan 494 hasta retrospektif olarak çalışmaya dahil edildi. Poliklinik hizmet ücreti ,antikoagülanların neden olduğu kanama nedeniyle hastaneye yatış ücretleri ve antikoagülan ilaç maliyeti dahil edilerek Sosyal Güvenlik Kurumunca ödenen ücretlerin karşılaştırılması yapıldı.
Bulgular: Çalışma grubunda antikoagülan ilaç kullanıcılarının %18.8'i varfarin, %81.2'si NOACs kullanıyordu. Varfarin kullanan hastalarda poliklinik muayene hizmet sayısı daha yüksekti. Hasta grupları arasında cinsiyet açısından istatistiksel bir fark görülmedi fakat NOAC kullanan hastalarda ortalama yaş daha yüksekti (p<0.026). Varfarin kullanan hastalarda poliklinik muayene hizmet ve hastaneye yatış ücretleri daha yüksek fakat NOAC hastalarında toplam maliyetler daha yüksekti (p<0.001).
Sonuç: NOAC ilaçlarının hemorajik komplikasyonları ve hastaneye yatış sıklığı düşüktür ve poliklinik muayene ücretleri açısından daha avantajlıdr. NOAC ilaçlarının fiyatları daha düşük olsa, toplam maliyet azalacak ve bu ilaçlar varfarin'e göre toplam maliyet açısından daha avantajlı olacaktır

Keywords

Yeni nesil oral antikoagülan, varfarin, maliyet analizi

Treatment Cost Analysis Study In Patients with Atrial Fibrillation Using Warfarin or New Generation Oral Anticoagulant

Abstract

Objective:We compared the cost analysis of warfarin and new-generation oral anticoagulant (NOAC) treatment in patients with atrial fibrillation.

Materials and Methods:Four hundred and ninety-four patients diagnosed with atrial fibrillation at the cardiology outpatient clinic (OC) and using warfarin or NOAC therapy were retrospectively included in the study.Comparison of the total cost of OC and examination fees paid by the social security institution; Fees related to hospitalizations due to hemorrhage caused by anticoagulants and anticoagulant drug cost were compared.

Results: In the study group, 18.8% of the anticoagulant drug users were using warfarin, and 81.2% were using NOACs. The average number of admission to OC is more prevalent in patients using warfarin. No statistical difference was observed in gender between patients, but patients using NOAC had a higher mean age (p<0.026).The costs of OC examination and hospitalization were higher in patients receiving warfarin medication but the total costs were higher in NOAC patients (p<0.001).

Conclusion:Hemorrhagic complications of NOAC drugs and hospitalization frequency are low, and the cost of OC examination is beneficial. If the NOAC prices are lower, the total cost will be reduced and these drugs will be more favorable than warfarin.

Keywords

New-generation oral anticoagulant, warfarin, cost analysis

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