Gonartrozlu Hastalarda Trigliserit Glikoz İndeksi ile Nötrofil Lenfosit Oranı Arasındaki İlişki

Year 2023, Volume: 13 Issue: 1, 41 - 47, 16.03.2023

Zeynep Ergenç Hasan Ergenç Sami Oflaz

https://doi.org/10.31832/smj.1191878

Abstract

Amaç: Bu çalışmada, bu göstergelerin gonartroz gelişimindeki rolünü araştırmak için Trigliserit Glikoz, Nötrofil Lenfosit Oranı ve gonartroz hastalığı arasındaki ilişki araştırıldı.
Yöntem: Çalışmamızda 01.06.2022-01.10.2021 tarihleri ​​arasında ortopedi kliniğimizde takip edilen 50-84 yaş arası 141 hasta retrospektif olarak incelendi. Katılımcılar iki kontrol ve çalışma grubuna ayrıldı. Gonartroz tanısı alan katılımcılar çalışma grubuna, sağlıklı kontroller kontrol grubuna dahil edildi. Hastaların demografik özellikleri ve biyokimyasal verileri hasta dosyalarından ve elektronik kayıtlardan toplandı.
Bulgular: Hastaların yaşı 54±12.5 (18-75) idi. Çalışmamızdaki biyokimyasal parametrelerden açlık safra taşı olan olgularda plazma glukozu 124,6 ± 24,5 mg/dL, trigliserit 198.3 ± 36,8 mg/dL, insülin 16,5 ± 5,6 uIU/mL, HOMA-IR 4 düzeyi ,8± 1.2, hepsinde kontrol grubuna göre istatistiksel olarak anlamlı derecede yüksekti (p=0.001). TGYI gruba göre anlamlı farklılık göstermektedir (p<0.05). Gonartroz grubundakilerin ortalaması 4,3±0,22 iken kontrol grubundakilerin ortalaması 4,21±0,08 idi. NEUCRP gruba göre anlamlı farklılık göstermektedir (p<0.05). Gonartroz grubundakilerin ortalaması 3.02±5.55 iken kontrol grubundakilerin ortalaması 1.37±0.53 idi.
Sonuç: Sonuçlar, Trigliserit Glikoz İndeksi ve Nötrofil Lenfosit Oranı gibi metabolik sendrom indeksleri ile gonartroz arasında anlamlı bir ilişki olduğunu göstermiştir.

Keywords

Trigliserit Glikoz İndeksi, Nötrofil Lenfosit Oranı, Gonartroz

Association Between Triglyceride Glucose Index and Neutrophil Lymphocyte Ratio in Patients with Gonarthrosis

Abstract

Aim: This study investigated the relationship between Triglyceride Glucose, Neutrophil Lymphocyte Ratio, and gonarthrosis disease to investigate the role of these indicators in developing gonarthrosis.
Method: Our study retrospectively investigated 141 patients aged between 50-84 years old who underwent follow-up in our orthopedic clinic between 01.06.2022-01.10.2021. The participants were divided into two control and study groups. Participants diagnosed with gonarthrosis were included in the study group, and healthy controls were included in the control group. Demographic characteristics of the patients and biochemical data were collected from patient files and electronic records.
Results: The age of the patients was 54±12.5 (18-75) years. Among the biochemical parameters in our study, in cases with fasting gallstones, plasma glucose is 124.6 ± 24.5 mg/dL, triglyceride 198.3 ± 36.8 mg/dL, insulin 16.5 ± 5.6 uIU/mL, HOMA-IR 4 The level of .8±1.2 was statistically significantly higher in all of them compared to the control group (p=0.001). TGYI shows a significant difference according to the group (p<0.05). The mean of those in the gonarthrosis group was 4.3±0.22, while the mean of those in the control group was 4.21±0.08. NEUCRP shows a significant difference according to the group (p<0.05). While the mean of those in the gonarthrosis group was 3.02±5.55, the mean of those in the control group was 1.37±0.53.
Conclusion: Results showed a significant association between metabolic syndrome indexes, such as Triglyceride Glucose Index and Neutrophil Lymphocyte Ratio, and gonarthrosis.

Keywords

Triglyceride Glucose Index, Neutrophil Lymphocyte Ratio, Gonarthrosis

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