Abstract
Nephrotic syndrome is characterized by diffuse edema, massive proteinuria and hypoalbuminemia. It usually occurs between the ages of 2-6. Due to periorbital edema these patients are mistakenly diagnosed with allergic disease. A 4-year-old 9-month-old male patient, who had no known disease under follow-up, was admitted to the pediatric surgery service due to bilateral hydrocele and inguinal hernia, was planned to be operated on, and bilateral swelling in his eyes was noticed in the preoperative evaluation, was consulted to the pediatric immunology-allergy department. His general condition was good, his skin turgor was normal, his eyelids were edematous. There was bilateral pretibial pitting edema and bilateral transluminated swelling in the scrotum. In laboratory examination: Albumin: 1.6g/dl, Sedimentation:76 mm/hr, C3:1.23 mg/dl, and C4: 0.24 mg/dl. In urine: density: 1051, protein: +++, protein/creatinine was 17.8 mg/mg. Both nephrotic syndrome and angioedema cause severe edema of the eyelids and genital area. Therefore, laboratory tests, clinical findings and careful examination are sufficient for differential diagnosis. In our study, we aimed to present a case of nephrotic syndrome with a prediagnosis of allergic angioedema.
Nefrotik sendrom yaygın ödem, masif proteinüri ve hipoalbuminemi ile karakterize, sıklıkla 2-6 yaşlarında oluşan bir sendromdur. Genellikle gün içinde azalan periorbital ödem nedeniyle bu hastalar yanlışlıkla alerjik hastalık tanısı almaktadır. Daha önceden bilinen takipli hastalığı olmayan, bilateral hidrosel ve inguinal herni nedeniyle ameliyatı planlanan, operasyon öncesi değerlendirmede gözlerinde bilateral şişlik farkedilen 4 yaş 9 aylık erkek hasta, anjioödem ön tanısı ile çocuk immünoloji alerji bölümüne konsülte edildi. Göz kapakları ödemli, bilateral pretibial gode bırakan ödem ve skrotumda bilateral translüminasyon gösteren şişlik olan hastanın diğer muayeneleri normaldi. Laboratuvar incelemesinde: Albumin: 1.6g/dl, Sedimentasyon:76 mm/saat, C3:1,23 mg/dl, ve C4: 0,24 mg/dl. İdrarda: dansite: 1051, protein: +++, protein/kreatinin 17,8 mg/mg idi. Hem nefrotik sendrom hem de anjioödem göz kapaklarında, genital bölgede ciddi ödem oluşturur. Bu nedenle laboratuvar tetkikleri, klinik bulgular, dikkatli muayene ayırıcı tanı için yeterlidir. Çalışmamızda alerjik anjioödem ön tanılı nefrotik sendrom olgusunu sunmayı amaçladık.
Primary Language | Turkish |
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Subjects | Health Care Administration |
Journal Section | Case Report |
Authors | |
Early Pub Date | March 31, 2024 |
Publication Date | March 31, 2024 |
Submission Date | October 14, 2021 |
Published in Issue | Year 2024 Volume: 14 Issue: 1 |
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