One-Year Retrospective Analysis of Adolescent Substance Use Treatment Clinic Cases

Year 2025, Volume: 15 Issue: 3, 239 - 248, 30.09.2025

Mustafa Tolga Tunagür , Enes Sarıgedik

https://doi.org/10.31832/smj.1740901

Abstract

Objective: This study aimed to examine the sociodemographic, clinical, psychosocial, and substance use characteristics of adolescents admitted to an outpatient Child and Adolescent Substance Addiction Treatment Center (ÇEMATEM) in Türkiye. It also compared adolescents who used a single substance with those who used multiple substances (polysubstance users).
Materials and Methods: The study retrospectively reviewed the medical records of 66 adolescents over a one-year period. Standardized assessment tools, including the Addiction Profile Index Adolescent Form (API-A) and the Substance Craving Scale (SCS), were used.
Results: The mean age of the sample was 15.97 ± 1.51 years. Polysubstance use was observed in 66.7% of the sample. Compared to monosubstance users, polysubstance users were more likely to be female, slightly older, and had significantly higher rates of prior hospitalization and suicide attempts. They also exhibited significantly higher levels of craving and addiction severity across all API-A domains. The most commonly used substances were alcohol, cannabinoids, stimulants, and methamphetamine. Half of the sample reported concurrent use of alcohol, stimulants, and cannabinoids.
Conclusions: Polysubstance use among adolescents is associated with greater psychosocial burden and clinical severity. These findings underscore the need for early identification and tailored interventions for this high-risk group.

Keywords

Suicide , Adolescent , Substance-related disorders , Risk factors , Cannabinoids , Polysubstance

References

• Coelho JM, Peixoto C, Bicho M, Fontes H. Substance use disorders in adolescence - a review. European Psychiatry. 2021;64(S1):S826-S827. doi:10.1192/j.eurpsy.2021.2183
• SAMHSA. Key substance use and mental health indicators in the United States: Results from the 2022 National Survey on Drug Use and Health (HHS Publication No. PEP23-07-01-006, NSDUH Series H-58). 2023. Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. Accessed July 30, 2025.
• ESPAD-Group. ESPAD Report 2019: Results from the European School Survey Project on Alcohol and Other Drugs. 2020. EMCDDA Joint Publications. Accessed July 30, 2025. https://www.euda.europa.eu/publications/joint-publications/espad-report-2019_en
• Turkey Country Drug Report 2019. European Monitoring Centre for Drugs and Drug Addiction. Accessed July 30, 2025. https://www.euda.europa.eu/system/files/publications/11356/turkey-cdr-2019.pdf
• Turkish Drug Report 2019. Republic of Turkey, Ministry of Interior, Turkish National Police, Counter Narcotics Department. Accessed July 30, 2025. https://www.narkotik.pol.tr/kurumlar/narkotik.pol.tr/TUB%C4%B0M/Ulusal%20Yay%C4%B1nlar/2019-TURKISH-DRUG-REPORT_30122019.pdf
• Kurt Tunagur EM, Yazici AB, Guzel D, et al. Investigating associations between appetite-regulating hormones, aggression, and craving in males with cannabis use disorder. Drug Alcohol Depend. Sep 1 2022;238:109577. doi:10.1016/j.drugalcdep.2022.109577
• Tomczyk S, Isensee B, Hanewinkel R. Latent classes of polysubstance use among adolescents: A systematic review. Drug Alcohol Depend. Mar 1 2016;160:12-29. doi:10.1016/j.drugalcdep.2015.11.035
• Merrin GJ, Thompson K, Leadbeater BJ. Transitions in the use of multiple substances from adolescence to young adulthood. Drug Alcohol Depend. Aug 1, 2018;189:147-153. doi:10.1016/j.drugalcdep.2018.05.015
• Black N, Noghrehchi F, Yuen WS, et al. Transitions to polysubstance use: Prospective cohort study of adolescents in Australia. Addiction. Jun 2024;119(6):1100-1110. doi:10.1111/add 16468
• Goodwin SR, Moskal D, Marks RM, Clark AE, Squeglia LM, Roche DJO. A scoping review of gender, sex, and sexuality differences in polysubstance use in adolescents and adults. Alcohol Alcohol. May 10, 2022;57(3):292-321. doi:10.1093/alcalc/agac006
• Chan GC, Kelly AB, Carroll A, Williams JW. Peer drug use and adolescent polysubstance use: Do parenting and school factors moderate this association? Addict Behav. Jan 2017;64:78-81. doi:10.1016/j.addbeh.2016.08.004
• Watts LL, Hamza EA, Bedewy DA, Moustafa AA. A meta-analysis study on peer influence and adolescent substance use. Current Psychology. 2024/02/01 2024;43(5):3866-3881. doi:10.1007/s12144-023-04944-z
• Catalano RF, Haggerty KP, Oesterle S, Fleming CB, Hawkins JD. The importance of bonding to school for healthy development: Findings from the Social Development Research Group. J Sch Health. Sep 2004;74(7):252-261. doi:10.1111/j.1746-1561.2004.tb08281.x
• Gardvik KS, Rygg M, Torgersen T, Lydersen S, Indredavik MS. Psychiatric morbidity, somatic comorbidity and substance use in an adolescent psychiatric population at 3-year follow-up. Eur Child Adolesc Psychiatry. Jul 2021;30(7):1095-1112. doi:10.1007/s00787-020-01602-8
• Green R, Wolf BJ, Chen A, et al. Predictors of Substance Use Initiation by Early Adolescence. Am J Psychiatry. May 1, 2024;181(5):423-433. doi:10.1176/appi.ajp.20230882
• Kardaş Ö, Kardaş B. Çocuk ve ergen madde bağımlılığı tedavi merkezine başvuran olguların sosyodemografik ve madde kullanım özelliklerinin incelenmesi. Bağımlılık Dergisi. June 2023;24(2):174-185. doi:10.51982/bagimli.1112645
• Sirin H, Uzun ME. Sociodemographic and clinical characteristics of adolescent patients treated in ÇEMATEM with the diagnosis of substance use disorders: Bursa sample. Turk J Child Adolesc Ment Health. 2021;28(2):151-158. doi:10.4274/tjcamh.galenos.2021.46330
• Ciftci Demirci A, Erdogan A, Yalcin O, et al. Sociodemographic characteristics and drug abuse patterns of adolescents admitted for substance use disorder treatment in Istanbul. Am J Drug Alcohol Abuse. May 2015;41(3):212-219. doi:10.3109/00952990.2014.973961
• Kuygun Karcı C, Arıcı Gürbüz A, Akkuş Özdemir F, Altun Varmış D, Yolga Tahiroğlu A. Madde kullanan ergenlerde psikiyatrik eş tanı, bağımlılık profili ve tedavi isteği: ÇEMATEM verileri. Psychiatric Comorbidity, Addiction Profile and Desire for Treatment in Substance-Using Adolescents: ÇEMATEM Data. Bağımlılık Dergisi. March 2022;23(1):61-68. doi:10.51982/bagimli.956300
• Ögel K, Evren C, Karadağ F, Gürol DT. Bağımlılık profil indeksi'nin (BAPİ) geliştirilmesi, geçerlik ve güvenilirliği. Türk Psikiyatri Dergisi. 2012;23(4):264-273.
• Evren C, Gürol DT, Ögel K, Karadağ F. Reliability and validity of the Penn Alcohol Craving Scale (PACS) revised version for substance craving in male substance-dependent inpatients. Türk Psikiyatri Dergisi. 2011;(Suppl. 1):70.
• Halladay J, Woock R, El-Khechen H, et al. Patterns of substance use among adolescents: A systematic review. Drug Alcohol Depend. Nov 1 2020;216:108222. doi:10.1016/j.drugalcdep.2020.108222
• Chopra R, Sylvestre M-P, Pelekanakis A, Doré I, Omorou AY, O’Loughlin J. Polysubstance use and mental health among young adults. Canadian Journal of Public Health. 2025 April29. doi:10.17269/s41997-025-01035-3
• Hochheimer M, Strickland JC, Rabinowitz JA, et al. The impact of opioid-stimulant co-use on tonic and cue-induced craving. J Psychiatr Res. Aug 2023;164:15-22. doi:10.1016/j.jpsychires.2023.05.018
• Carbonneau R, Vitaro F, Brendgen M, Tremblay RE. Longitudinal patterns of polysubstance use throughout adolescence: Association with adult substance use and psychosocial outcomes controlling for preadolescent risk factors in a male cohort. Soc Psychiatry Psychiatr Epidemiol. Oct 2023;58(10):1469-1481. doi:10.1007/s00127-023-02454-8
• Rodzlan Hasani WS, Saminathan TA, Ab Majid NL, et al. Polysubstance use among adolescents in Malaysia: Findings from the National Health and Morbidity Survey 2017. PLoS One. 2021;16(1):e0245593. doi:10.1371/journal.pone.0245593
• Farmer E, Ingram P, Finn P. Sex differences in polysubstance use symptoms: A network analysis. International Journal of Mental Health and Addiction. 2025 January 28. doi:10.1007/s11469-025-01449-7
• Bilaç Ö, Kavurma C, Önder A, Doğan Y, Uzunoğlu G, Ozan E. A clinical and sociodemographic evaluation of youths with substance use disorders in a child and adolescent inpatient unit of a mental health hospital (Turkey). Turkish J Clin Psy. 2019;22(4):463-471. doi:10.5505/kpd.2019.30075
• Yildiz D, Ciftci A, Yalcin O. Substance use patterns, psychosocial traumas, psychiatric comorbidities, and gender differences among adolescent inpatients at an addiction treatment center. Dusunen Adam. 2020;33(2):190-202. doi:10.14744/DAJPNS.2020.00078