ELİT TÜRK GÜREŞÇİLERİNİN ANJİOTENSİN I-DÖNÜŞTÜRÜCÜ ENZİM GEN POLİMORFİZMİ VE VO2MAX DÜZEYLERİ İLE ATLETİK PERFORMANS ARASINDAKİ İLİŞKİNİN BELİRLENMESİ

Year 2019, Volume: 17 Issue: 4, 275 - 284, 30.12.2019

Melahat Kurtuluş Mehmet Günay Çağrı Çelenk İbrahim Cicioğlu Tahsin Kesici

https://doi.org/10.33689/spormetre.641112

Cited By: 1

Abstract

Anjiotensin I-dönüştürücü
enzim gen polimorfizmi fiziksel aktivite ile ilişkili önemli genlerden biridir.
Bu çalışmanın amacı, elit Türk güreşçilerde ADE I/D gen polimorfizmi ile
atletik performans ve ADE geni genotip dağılımı ile maksimum oksijen tüketimi
(Vo2max) arasında bir ilişki olup olmadığını belirlemektir. ADE I/D
gen polimorfizmi 46 elit Türk güreşçi ve 58 sağlıklı sedanter bireyde
araştırıldı. Elit güreşçilerin Vo2max değerleri mekik koşu testi ile
ölçüldü. Elit güreşçi ve sedanter bireylerin DNA’sı periferal kandan elde
edildi. ADE I/D gen polimorfizmi alel frekansları ve genotip dağılımı polimeraz zincir reaksiyonu ile belirlendi. Elit
güreşçi ve sedanter bireylerin ACE I/D gen polimorfizmi alel frekansları ve
genotip dağılımı karşılaştırıldı ve elit güreşçi ve sedanter bireyler arasında önemli
bir fark bulunmadı (P>0.05). Elit güreşçilerin ADE I/D gen polimorfizmi
genotip dağılımı ile Vo2max düzeyleri arasında bir fark tespit
edilmedi (P>0.05). Vo2max düzeylerinin DD, ID ve II
genotipli elit güreşçilerde benzer dağılım gösterdiği belirlendi. Bu araştırma
elit Türk güreşçilerinde ADE I/D gen polimorfizmi ile spor performansı ve ACE I/D
gen polimorfizmi genotipleri ile Vo2max arasında anlamlı bir ilişki
olmadığını göstermiştir.  

Keywords

Anjiotensin dönüştürücü enzim, Atletik Performans, Güreş, Polimorfizm, Vo2max

Supporting Institution

Gazi Üniversitesi

Project Number

02/2010-33

Thanks

Gazi Üniversitesine desteğinden dolayı teşekkür ederiz.

DETERMINATION OF THE RELATIONSHIP BETWEEN ANGIOTENSIN I-CONVERTING ENZYME GENE POLYMORPHISM AND VO2MAX LEVELS AND ATHLETIC PERFORMANCE IN ELITE TURKISH WRESTLERS

Abstract

The polymorphism of angiotensin I-converting
enzyme gene is one of the important genes associated with physical activity,
The aim of this study is to determine whether there is a relationship between
ACE I/D gene polymorphism and athletic performance and genotype distribution of
the ACE gene and maximum oxygen consumption (Vo2max) in the elite
Turkish wrestlers. ACE I/D gene polymorphism is investigated in 46 elite
Turkish wrestlers and 58 healthy sedentary individuals. Vo2max
values in elite wrestlers were measured by a progressive shuttle run test. DNA of elite wrestlers and
sedentary individuals was obtained from peripheral blood. The allele
frequencies and genotype distribution of ACE I/D gene polymorphism determined
by polymerase chain reaction. Allele frequencies and genotype distribution of
ACE I/D gene polymorphism in the elite wrestlers and sedentary individuals were
compared and no significant difference was found between elite wrestlers and
sedentary individuals (P>0.05). There was also no
difference between the genotype distribution of the ACE I/D gene polymorphism
and Vo2max levels in the elite wrestlers  (P>0.05). It was determined
that Vo2max showed similar distribution in elite wrestlers with DD,
ID and II genotypes. The present study demonstrated that there was no
significant relationship between the ACE I/D gene polymorphism and sports
performance and genotypes of ACE I/D gene polymorphism and Vo2max in
elite Turkish wrestlers.

Keywords

Angiotensin Converting Enzyme, Athletic Performance, Wrestling, Polymorphism, Vo2max

Project Number

02/2010-33

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