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OTİZM SPEKTRUM BOZUKLUĞUNDA FİZİKSEL AKTİVİTE MÜDAHALESİNİN BİLİŞSEL GELİŞİM ÜZERİNDEKİ ETKİSİ

Year 2025, Volume: 23 Issue: 3, 162 - 177
https://doi.org/10.33689/spormetre.1676676

Abstract

Elektroensefalografi (EEG) sinyalleri, zihinsel iş yükü değerlendirmelerinde sıklıkla kullanılmaktadır. Bu nedenle, Otizm Spektrum Bozukluğu (OSB) üzerinde yapılan spektral analizler, etiyolojiye ışık tutmak, semptomları azaltmak amacıyla müdahale programları geliştirmek, bu yöntemlerin etkilerini belirlemek ve nöral aktivitenin gelişimini anlamak için önemlidir. Bu çalışmanın amacı, fiziksel aktivite müdahalesinin otizm tanısı almış çocuklarda beyin aktivasyonu, otizm semptomları ve tekrarlayan davranışlardaki değişiklikler üzerindeki etkisini incelemektir. Çalışma, nicel ve deneysel araştırma tasarımlarından bir kontrol grubu ile ön ve son test tasarımı kullanılarak yapılmıştır. Otizm tanısı almış yirmi bir çocuk, ölçüt örnekleme yöntemiyle çalışmaya dahil edilmiştir. Beyinde yaratılan ani dalgalanmalarla öğrenme sürecinin daha etkili olacağı ilkesine dayanan, farklara dayalı öğrenme yaklaşımına dayalı bir fiziksel aktivite programı uygulanmıştır. Müdahale programının etkileri, tekrarlayan davranışsal ve sinirsel ölçümlerden elde edilen verilerle belirlenmiştir. Bulgular, müdahale programına katıldıktan sonra ASD'li çocuklarda görülen tekrarlayan davranışlardaki azalmayı açıklayabilecek karmaşık beyin süreçlerinin daha kapsamlı bir şekilde incelenmesine olanak sağlamaktadır.

Project Number

2022EĞBE003

References

  • Akşit, S., & Yılmaz, E. B. (2024). Egzersiz müdahalelerinin otizm spektrum bozukluğunda bilişsel sürece etkisi i̇le i̇lgili yapılmış çalışmaların sistematik derlemesi. Akdeniz Spor Bilimleri Dergisi, 7(1), 70-88. DOI: https://doi.org/10.38021asbid.1400492
  • Blanco, S., Garcia, H., Quiroga, R. Q., Romanelli, L., & Rosso, O. A. (1995). Stationarity of the EEG series. IEEE Engineering in Medicine and Biology Magazine, 14(4), 395-399. DOI: 10.1109/51.395321
  • Buzsáki, G., & Wang, X. J. (2012). Mechanisms of gamma oscillations. Annual Review of Neuroscience, 35, 203-225. DOI: 10.1146/annurev-neuro-062111-150444
  • Canolty, R. T., Edwards, E., Dalal, S. S., Soltani, M., Nagarajan, S. S., Kirsch, H. E., … & Knight, R. T. (2006). High gamma power is phase-locked to theta oscillations in human neocortex. Science, 313(5793), 1626–1628. https://doi.org/10.1126/science.1128115
  • Cai, K., Yu, Q., Herold, F., Liu, Z., Wang, J., Zhu, L., ve Zou, L. (2020). Mini-basketball training program improves social communication and white matter integrity in children with autism. Brain Sciences, 10(11), 803. DOI: 10.3390/brainsci10110803
  • Carter Leno, V., Tomlinson, S. B., Chang, S. A. A., Naples, A. J., & McPartland, J. C. (2018). Resting-state alpha power is selectively associated with autistic traits reflecting behavioral rigidity. Scientific Reports, 8(1), 11982. DOI: 10.1038/s41598-018-30445-2
  • Casanova, M. F., Shaban, M., Ghazal, M., El-Baz, A. S., Casanova, E. L., & Sokhadze, E. M. (2021). Ringing decay of gamma oscillations and transcranial magnetic stimulation therapy in autism spectrum disorder. Applied Psychophysiology and Biofeedback, 46, 161-173. DOI: 10.1007/s10484-021-09509-z
  • Chan, A. S., Han, Y. M., Sze, S. L., & Lau, E. M. (2015). Neuroenhancement of memory for children with autism by a mind–body exercise. Frontiers in Psychology, 6, 1893. https://doi.org/10.3389/fpsyg.2015.01893
  • Chan, A. S., Sze, S. L., & Cheung, M. C. (2007). Quantitative electroencephalographic profiles for children with autistic spectrum disorder. Neuropsychology, 21(1), 74–81. https://doi.org/10.1037/0894-4105.21.1.74. DOI: 10.1037/0894-4105.21.1.74
  • Chan, K. L. R., & Ouyang, G. (2024). Impact of child-centered play therapy intervention on children with autism reflected by brain EEG activity: A randomized controlled trial. Research in Autism Spectrum Disorders, 112, 102336. DOI: 10.1016/j.rasd.2024.102336
  • Choktanomsup, K., Charoenwat, W., & Sittiprapaporn, P. (2017). Changes of EEG power spectrum in moderate running exercises. In 2017 14th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology (ECTI-CON), 9-12. EEE. DOI: 10.1109/ECTICon.2017.8096161
  • Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences (2nd ed.). Hillsdale, NJ: Lawrence Earlbaum Associates.
  • Colcombe, S., & Kramer, A. F. (2003). Fitness effects on the cognitive function of older adults: a meta-analytic study. Psychological Science, 14(2), 125-130. DOI: 10.1111/1467-9280.t01-1-01430
  • Comsa, I. M., Bekinschtein, T. A., & Chennu, S. (2019). Transient topographical dynamics of the electroencephalogram predict brain connectivity and behavioural responsiveness during drowsiness. Brain Topography, 32(2), 315–331. https://doi.org/10.1007/s10548-018-0689-9
  • Dickinson, A., DiStefano, C., Senturk, D., & Jeste, S. S. (2018). Peak alpha frequency is a neural marker of cognitive function across the autism spectrum. European Journal of Neuroscience, 47(6), 643–651. https://doi.org/10.1111/ejn.13645
  • Dickinson, A., Bruyns‐Haylett, M., Jones, M., & Milne, E. (2015). Increased peak gamma frequency in individuals with higher levels of autistic traits. European Journal of Neuroscience, 41(8), 1095-1101. https://doi.org/10.1111/ejn.12881
  • Diken, İ. H., Ardıç, A., Diken, Ö., & Gilliam, J. E. (2012). Gilliam otistik bozukluk derecelendirme ölçeği-2 Türkçe versiyonu’nun (GOBDÖ-2-TV) geçerlik ve güvenirliğinin araştırılması: Türkiye standardizasyon çalışması. Eğitim ve Bilim, 37(166).
  • Duru, A.D. (2019). Determination of ıncreased mental workload condition from eeg by the use of classification techniques. International Journal of Advances in Engineering and Pure Sciences, 1, 47- 52. https://doi.org/10.7240/jeps.459420
  • Enriquez-Geppert, S., Huster, R. J., & Herrmann, C. S. (2017). EEG-neurofeedback as a tool to modulate cognition and behavior: A review tutorial. Frontiers in Human Neuroscience, 11, 51. https://doi.org/10.3389/fnhum.2017.00051
  • Faul, F., Erdfelder, E., Lang, A. G., & Buchner, A. (2007). G* Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39(2), 175-191. doi: 10.3758/bf03193146.
  • Fauzan, N., & Amran, N. H. (2015). Brain waves and connectivity of autism spectrum disorders. Procedia-Social and Behavioral Sciences, 171, 882-890. doi: 10.1016/j.sbspro.2015.01.204
  • Foxe, J. J., & Snyder, A. C. (2011). The role of alpha-band brain oscillations as a sensory suppression mechanism during selective attention. Frontiers in Psychology, 2, 10747. https://doi.org/10.3389/fpsyg.2011.00154
  • Gandhi, T., & Lee, C. C. (2021). Neural mechanisms underlying repetitive behaviors in rodent models of autism spectrum disorders. Frontiers in Cellular Neuroscience, 14, 592710. https://doi.org/10.3389/fncel.2020.592710
  • Garson, G. D. (2012). Testing statistical assumptions. Statistical Associates Publishing.
  • Gilliam, J. E. (2005). Gilliam autism rating scale (2nd ed.). Pro-Ed.
  • Gilliam, J. E. (1995). Gilliam autism rating scale (GARS). Pro-Ed.
  • Guerra, A., Bologna, M., Paparella, G., Suppa, A., Colella, D., Di Lazzaro, V., Brown, P. & Berardelli, A. (2018). Effects of transcranial alternating current stimulation on repetitive finger movements in healthy humans. Neural Plasticity. Article 4593095. https://doi.org/10.1155/2018/4593095
  • Höfer, J., Bachmann, C., Kamp-Becker, I., Poustka, L., Roessner, V., Stroth, S., ... & Hoffmann, F. (2019). Willingness to try and lifetime use of complementary and alternative medicine in children and adolescents with autism spectrum disorder in Germany: A survey of parents. Autism, 23(7), 1865-1870. DOI: 10.1177/1362361318823545
  • Jensen, O., Kaiser, J., & Lachaux, J. P. (2007). Human gamma-frequency oscillations associated with attention and memory. Trends in Neurosciences, 30(7), 317-324. DOI: 10.1016/j.tins.2007.05.001
  • Jensen, O., & Tesche, C. D. (2002). Frontal theta activity in humans increases with memory load in a working memory task. European Journal of Neuroscience, 15(8), 1395-1399. DOI: 10.1046/j.1460-9568.2002.01975.x
  • Kim, D., Lee, J. Y., Jeong, B. C., Ahn, J. H., Kim, J. I., Lee, E. S., ... & Han, C. E. (2021). Overconnectivity of the right Heschl’s and inferior temporal gyrus correlates with symptom severity in preschoolers with autism spectrum disorder. Autism Research, 14(11), 2314-2329. DOI: 10.1002/aur.2609
  • Kitaura, Y., Nishida, K., Yoshimura, M., Mii, H., Katsura, K., Ueda, S., ... & Kinoshita, T. (2017). Functional localization and effective connectivity of cortical theta and alpha oscillatory activity during an attention task. Clinical Neurophysiology Practice, 2, 193-200. https://doi.org/10.1016/j.cnp.2017.09.002
  • Knyazev, G. G. (2007). Motivation, emotion, and their inhibitory control mirrored in brain oscillations. Neuroscience & Biobehavioral Reviews, 31(3), 377-395. DOI: 10.1016/j.neubiorev.2006.10.004
  • Liang, X., Li, R., Wong, S. H., Sum, R. K., Wang, P., Yang, B., & Sit, C. H. (2022). The effects of exercise interventions on executive functions in children and adolescents with autism spectrum disorder: A systematic review and meta-analysis. Sports Medicine, 52(1), 75-88. DOI: 10.1007/s40279-021-01545-3
  • Lisman, J., & Buzsáki, G. (2008). A neural coding scheme formed by the combined function of gamma and theta oscillations. Schizophrenia Bulletin, 34(5), 974-980. DOI: 10.1093/schbul/sbn060
  • Lisman, J. E., & Jensen, O. (2013). The theta-gamma neural code. Neuron, 77(6), 1002-1016.
  • Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. The Lancet, 392(10146), 508-520. doi:10.1016/s0140-6736(18)31129-2
  • Macoun, S. J., Schneider, I., Bedir, B., Sheehan, J., ve Sung, A. (2021). Pilot study of an attention and executive function cognitive intervention in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 51, 2600-2610. DOI: 10.1007/s10803-020-04723-w
  • Magosso, E., De Crescenzio, F., Ricci, G., Piastra, S., & Ursino, M. (2019). EEG alpha power is modulated by attentional changes during cognitive tasks and virtual reality immersion. Computational intelligence and neuroscience, 2019, 7051079. https://doi.org/10.1155/2019/7051079
  • McVoy, M., Lytle, S., Fulchiero, E., Aebi, M. E., Adeleye, O., & Sajatovic, M. (2019). A systematic review of quantitative EEG as a possible biomarker in child psychiatric disorders. Psychiatry Res., 279, 331–44. DOI: 10.1016/j.psychres.2019.07.004
  • Nekar, D. M., Lee, D. Y., Hong, J. H., Kim, J. S., Kim, S. G., Seo, Y. G., ve Yu, J. H. (2022). Effects of augmented reality game-based cognitive–motor training on restricted and repetitive behaviors and executive function in patients with autism spectrum disorder. In Healthcare, 10, 10. DOI: 10.3390/healthcare10101981
  • Orekhova, E. V., Stroganova, T. A., Nygren, G., Tsetlin, M. M., Posikera, I. N., Gillberg, C., & Elam, M. (2007). Excess of high frequency electroencephalogram oscillations in boys with autism. Biological Psychiatry, 62(9), 1022-1029. https://doi.org/10.1016/j.biopsych.2006.12.029
  • Ökcün Akçamuş, M. Ç., Bakkaloğlu, H., Demir, Ş., & Bahap Kudret, Z. (2019). Otizm spektrum bozukluğunda Tekrarlayıcı Davranışlar Ölçeği-Revize Türkçe Sürümünün geçerlilik ve güvenilirlik çalışması. Anadolu Psikiyatri Dergisi, 20. Doi: 10.5455/apd.42649
  • Rafiei Milajerdi, H., Sheikh, M., Najafabadi, M. G., Saghaei, B., Naghdi, N., & Dewey, D. (2021). The effects of physical activity and exergaming on motor skills and executive functions in children with autism spectrum disorder. Games for Health Journal, 10(1), 33-42. https://doi.org/10.1089/g4h.2019.0180
  • Ray, S., Niebur, E., Hsiao, S. S., Sinai, A., & Crone, N. E. (2008). High-frequency gamma activity (80–150 Hz) is increased in human cortex during selective attention. Clinical Neurophysiology, 119(1), 116-133. https://doi.org/10.1016/j.clinph.2007.09.136
  • Salari, N., Rasoulpoor, S., Rasoulpoor, S., Shohaimi, S., Jafarpour, S., Abdoli, N., ... & Mohammadi, M. (2022). The global prevalence of autism spectrum disorder: a comprehensive systematic review and meta-analysis. Italian Journal of Pediatrics, 48(1), 112. https://doi.org/10.1186/s13052-022-01310-w
  • Schöllhörn, I., Hegen, P., & Davids, K. (2012). The nonlinear nature of learning-a differential learning approach. The Open Sports Sciences Journal, 5(1). DOI: 10.2174/1875399X01205010100
  • Schöllhorn, W. I. (2000). Practical consequences of systems dynamic approach to technique and strength training. Acta Academiae Olympique Estonia, 8, 25–37.
  • Schöllhorn, W. (1994). Comparison of biomechanical movement patterns by means of orthogonal reference functions. In ISBS-Conference Proceedings Archive.
  • Sert, G. (2020). Otizmli çocuklarda uygulanan farklılıkla öğrenme egzersizlerinin denge ve üst ekstremite koordinasyonu üzerine etkisi. Düzce Üniversitesi, Sağlık bilimleri Enstitüsü, Beden Eğitimi ve Spor Anabilim Dalı. Yüksek Lisans Tezi.
  • Shahane, V., Kilyk, A., & Srinivasan, S. M. (2024). Effects of physical activity and exercise-based interventions in young adults with autism spectrum disorder: A systematic review. Autism, 28(2), 276-300. DOI: 10.1177/13623613231169058
  • Sharma, A., & Singh, M. (2015). Assessing alpha activity in attention and relaxed state: An EEG analysis. International Conference on Next Generation Computing Technologies. 508-513. DOI: 10.1109/NGCT.2015.7375171
  • Snijders, T. M., Milivojevic, B., & Kemner, C. (2013). Atypical excitation–inhibition balance in autism captured by the gamma response to contextual modulation. NeuroImage: Clinical, 3, 65-72. DOI: 10.1016/j.nicl.2013.06.015
  • Stillman, C. M., Esteban-Cornejo, I., Brown, B., Bender, C. M., & Erickson, K. I. (2020). Effects of exercise on brain and cognition across age groups and health states. Trends in Neurosciences, 43(7), 533-543. DOI: 10.1016/j.tins.2020.04.010
  • Strofylla, G., Charitou, S., Asonitou, K., ve Koutsouki, D. (2021). Efficacy of 6-Month Adapted Aerobic Program on Motor Proficiency, BMI and Cognitive Abilities of Students with Autism Spectrum Disorder: Three Case Reports. Open Journal of Social Sciences, 9(9), 153-166. DOI: 10.4236/jss.2021.99011
  • Van Diessen, E., Senders, J., Jansen, F. E., Boersma, M., & Bruining, H. (2015). Increased power of resting-state gamma oscillations in autism spectrum disorder detected by routine electroencephalography. European Archives of Psychiatry and Clinical Neuroscience, 265, 537-540. DOI 10.1007/s00406-014-0527-3
  • Wang, Y., Sokhadze, E. M., El-Baz, A. S., Li, X., Sears, L., Casanova, M. F., & Tasman, A. (2016). Relative power of specific EEG bands and their ratios during neurofeedback training in children with autism spectrum disorder. Frontiers in Human Neuroscience, 9, 723. https://doi.org/10.3389/fnhum.2015.00723
  • Wang, J. G., Cai, K. L., Liu, Z. M., Herold, F., Zou, L., Zhu, L. N., ve Chen, A. G. (2020). Effects of mini-basketball training program on executive functions and core symptoms among preschool children with autism spectrum disorders. Brain sciences, 10(5), 263. DOI: 10.3390/brainsci10050263
  • Wantzen, P., Clochon, P., Doidy, F., Wallois, F., Mahmoudzadeh, M., Desaunay, P., ... & Guillery-Girard, B. (2022). EEG resting-state functional connectivity: evidence for an imbalance of external/internal information integration in autism. Journal of Neurodevelopmental Disorders, 14(1), 1-14. https://doi.org/10.1186/s11689-022-09456-8
  • Yano, N., & Hosokawa, K. (2023). The importance of comprehensive support based on the three pillars of exercise, nutrition, and sleep for improving core symptoms of autism spectrum disorders. Frontiers in Psychiatry, 14, 1119142. https://doi.org/10.3389/fpsyt.2023.1119142
  • Zhang, Y., Tian, H., Tao, Y., Li, Y., Wang, D., ve Qin, L. (2023). A study on the effects of three game intervention programs on executive functions of preschool autistic children. International Journal of Developmental Disabilities, 1-11. https://doi.org/10.1080/20473869.2023.2215606
  • Zhao, H. C., Lv, R., Zhang, G. Y., He, L. M., Cai, X. T., Sun, Q., ... & Fu, B. (2022). Alterations of prefrontal-posterior information processing patterns in autism spectrum disorders. Frontiers in Neuroscience, 15, 768. https://doi.org/10.3389/fnins.2021.768219

EFFECT OF PHYSICAL ACTIVITY INTERVENTION ON COGNITIVE DEVELOPMENT IN AUTISM SPECTRUM DISORDER

Year 2025, Volume: 23 Issue: 3, 162 - 177
https://doi.org/10.33689/spormetre.1676676

Abstract

Electroencephalography (EEG) signals are frequently used in mental workload assessments. Therefore, spectral analysis in Autism Spectrum Disorder (ASD) is considered necessary to shed light on the aetiology, to develop intervention programs to reduce symptoms, to determine the effects of these methods, and to understand the development of neuronal activity. This study aims to examine the effects of physical activity on brain activation, autism symptoms, and repetitive behavioral changes in children with ASD. The model of this study is a pre and post-test design with a control group from quantitative and experimental research designs. 21 children with ASD were included in the study using the criterion sampling method. A physical activity program based on the learning by difference approach was implemented, based on the principle that the learning process would be more effective with sudden fluctuations created in the brain. The effects of the program were determined using data obtained from repeated behavioral and neural measurements. The findings pave the way for a more comprehensive examination of the complex brain processes that may be responsible for the reduction in repetitive behaviors exhibited by children with ASD.

Ethical Statement

The doctoral thesis titled "Effects of Physical Activity Intervention on Brain and Cognitive Development in Children Diagnosed with Autism Spectrum Disorder: An EEG Study" was presented as an oral presentation at the 21st Sports Sciences Congress, Antalya.

Supporting Institution

Pamukkale University Scientific Research Projects Coordination

Project Number

2022EĞBE003

Thanks

This article is derived from the doctoral dissertation entitled “Effects of Physical Activity Intervention on Brain and Cognitive Development in Children Diagnosed with Autism Spectrum Disorder: An EEG Study” and was supported by the Scientific Research Projects Coordination Unit of Pamukkale University.. I sincerely thank the Unit for its support. I would also like to express my heartfelt gratitude to Prof. Dr. Hakan Levent Gül, from the Medical Park Hospitals Group and Istanbul Rumeli University, and to Prof. Dr. Adil Deniz Duru, from the Faculty of Sport Sciences at Marmara University, for their valuable contributions and continuous support throughout this process.

References

  • Akşit, S., & Yılmaz, E. B. (2024). Egzersiz müdahalelerinin otizm spektrum bozukluğunda bilişsel sürece etkisi i̇le i̇lgili yapılmış çalışmaların sistematik derlemesi. Akdeniz Spor Bilimleri Dergisi, 7(1), 70-88. DOI: https://doi.org/10.38021asbid.1400492
  • Blanco, S., Garcia, H., Quiroga, R. Q., Romanelli, L., & Rosso, O. A. (1995). Stationarity of the EEG series. IEEE Engineering in Medicine and Biology Magazine, 14(4), 395-399. DOI: 10.1109/51.395321
  • Buzsáki, G., & Wang, X. J. (2012). Mechanisms of gamma oscillations. Annual Review of Neuroscience, 35, 203-225. DOI: 10.1146/annurev-neuro-062111-150444
  • Canolty, R. T., Edwards, E., Dalal, S. S., Soltani, M., Nagarajan, S. S., Kirsch, H. E., … & Knight, R. T. (2006). High gamma power is phase-locked to theta oscillations in human neocortex. Science, 313(5793), 1626–1628. https://doi.org/10.1126/science.1128115
  • Cai, K., Yu, Q., Herold, F., Liu, Z., Wang, J., Zhu, L., ve Zou, L. (2020). Mini-basketball training program improves social communication and white matter integrity in children with autism. Brain Sciences, 10(11), 803. DOI: 10.3390/brainsci10110803
  • Carter Leno, V., Tomlinson, S. B., Chang, S. A. A., Naples, A. J., & McPartland, J. C. (2018). Resting-state alpha power is selectively associated with autistic traits reflecting behavioral rigidity. Scientific Reports, 8(1), 11982. DOI: 10.1038/s41598-018-30445-2
  • Casanova, M. F., Shaban, M., Ghazal, M., El-Baz, A. S., Casanova, E. L., & Sokhadze, E. M. (2021). Ringing decay of gamma oscillations and transcranial magnetic stimulation therapy in autism spectrum disorder. Applied Psychophysiology and Biofeedback, 46, 161-173. DOI: 10.1007/s10484-021-09509-z
  • Chan, A. S., Han, Y. M., Sze, S. L., & Lau, E. M. (2015). Neuroenhancement of memory for children with autism by a mind–body exercise. Frontiers in Psychology, 6, 1893. https://doi.org/10.3389/fpsyg.2015.01893
  • Chan, A. S., Sze, S. L., & Cheung, M. C. (2007). Quantitative electroencephalographic profiles for children with autistic spectrum disorder. Neuropsychology, 21(1), 74–81. https://doi.org/10.1037/0894-4105.21.1.74. DOI: 10.1037/0894-4105.21.1.74
  • Chan, K. L. R., & Ouyang, G. (2024). Impact of child-centered play therapy intervention on children with autism reflected by brain EEG activity: A randomized controlled trial. Research in Autism Spectrum Disorders, 112, 102336. DOI: 10.1016/j.rasd.2024.102336
  • Choktanomsup, K., Charoenwat, W., & Sittiprapaporn, P. (2017). Changes of EEG power spectrum in moderate running exercises. In 2017 14th International Conference on Electrical Engineering/Electronics, Computer, Telecommunications and Information Technology (ECTI-CON), 9-12. EEE. DOI: 10.1109/ECTICon.2017.8096161
  • Cohen, J. (1988). Statistical Power Analysis for the Behavioral Sciences (2nd ed.). Hillsdale, NJ: Lawrence Earlbaum Associates.
  • Colcombe, S., & Kramer, A. F. (2003). Fitness effects on the cognitive function of older adults: a meta-analytic study. Psychological Science, 14(2), 125-130. DOI: 10.1111/1467-9280.t01-1-01430
  • Comsa, I. M., Bekinschtein, T. A., & Chennu, S. (2019). Transient topographical dynamics of the electroencephalogram predict brain connectivity and behavioural responsiveness during drowsiness. Brain Topography, 32(2), 315–331. https://doi.org/10.1007/s10548-018-0689-9
  • Dickinson, A., DiStefano, C., Senturk, D., & Jeste, S. S. (2018). Peak alpha frequency is a neural marker of cognitive function across the autism spectrum. European Journal of Neuroscience, 47(6), 643–651. https://doi.org/10.1111/ejn.13645
  • Dickinson, A., Bruyns‐Haylett, M., Jones, M., & Milne, E. (2015). Increased peak gamma frequency in individuals with higher levels of autistic traits. European Journal of Neuroscience, 41(8), 1095-1101. https://doi.org/10.1111/ejn.12881
  • Diken, İ. H., Ardıç, A., Diken, Ö., & Gilliam, J. E. (2012). Gilliam otistik bozukluk derecelendirme ölçeği-2 Türkçe versiyonu’nun (GOBDÖ-2-TV) geçerlik ve güvenirliğinin araştırılması: Türkiye standardizasyon çalışması. Eğitim ve Bilim, 37(166).
  • Duru, A.D. (2019). Determination of ıncreased mental workload condition from eeg by the use of classification techniques. International Journal of Advances in Engineering and Pure Sciences, 1, 47- 52. https://doi.org/10.7240/jeps.459420
  • Enriquez-Geppert, S., Huster, R. J., & Herrmann, C. S. (2017). EEG-neurofeedback as a tool to modulate cognition and behavior: A review tutorial. Frontiers in Human Neuroscience, 11, 51. https://doi.org/10.3389/fnhum.2017.00051
  • Faul, F., Erdfelder, E., Lang, A. G., & Buchner, A. (2007). G* Power 3: A flexible statistical power analysis program for the social, behavioral, and biomedical sciences. Behavior Research Methods, 39(2), 175-191. doi: 10.3758/bf03193146.
  • Fauzan, N., & Amran, N. H. (2015). Brain waves and connectivity of autism spectrum disorders. Procedia-Social and Behavioral Sciences, 171, 882-890. doi: 10.1016/j.sbspro.2015.01.204
  • Foxe, J. J., & Snyder, A. C. (2011). The role of alpha-band brain oscillations as a sensory suppression mechanism during selective attention. Frontiers in Psychology, 2, 10747. https://doi.org/10.3389/fpsyg.2011.00154
  • Gandhi, T., & Lee, C. C. (2021). Neural mechanisms underlying repetitive behaviors in rodent models of autism spectrum disorders. Frontiers in Cellular Neuroscience, 14, 592710. https://doi.org/10.3389/fncel.2020.592710
  • Garson, G. D. (2012). Testing statistical assumptions. Statistical Associates Publishing.
  • Gilliam, J. E. (2005). Gilliam autism rating scale (2nd ed.). Pro-Ed.
  • Gilliam, J. E. (1995). Gilliam autism rating scale (GARS). Pro-Ed.
  • Guerra, A., Bologna, M., Paparella, G., Suppa, A., Colella, D., Di Lazzaro, V., Brown, P. & Berardelli, A. (2018). Effects of transcranial alternating current stimulation on repetitive finger movements in healthy humans. Neural Plasticity. Article 4593095. https://doi.org/10.1155/2018/4593095
  • Höfer, J., Bachmann, C., Kamp-Becker, I., Poustka, L., Roessner, V., Stroth, S., ... & Hoffmann, F. (2019). Willingness to try and lifetime use of complementary and alternative medicine in children and adolescents with autism spectrum disorder in Germany: A survey of parents. Autism, 23(7), 1865-1870. DOI: 10.1177/1362361318823545
  • Jensen, O., Kaiser, J., & Lachaux, J. P. (2007). Human gamma-frequency oscillations associated with attention and memory. Trends in Neurosciences, 30(7), 317-324. DOI: 10.1016/j.tins.2007.05.001
  • Jensen, O., & Tesche, C. D. (2002). Frontal theta activity in humans increases with memory load in a working memory task. European Journal of Neuroscience, 15(8), 1395-1399. DOI: 10.1046/j.1460-9568.2002.01975.x
  • Kim, D., Lee, J. Y., Jeong, B. C., Ahn, J. H., Kim, J. I., Lee, E. S., ... & Han, C. E. (2021). Overconnectivity of the right Heschl’s and inferior temporal gyrus correlates with symptom severity in preschoolers with autism spectrum disorder. Autism Research, 14(11), 2314-2329. DOI: 10.1002/aur.2609
  • Kitaura, Y., Nishida, K., Yoshimura, M., Mii, H., Katsura, K., Ueda, S., ... & Kinoshita, T. (2017). Functional localization and effective connectivity of cortical theta and alpha oscillatory activity during an attention task. Clinical Neurophysiology Practice, 2, 193-200. https://doi.org/10.1016/j.cnp.2017.09.002
  • Knyazev, G. G. (2007). Motivation, emotion, and their inhibitory control mirrored in brain oscillations. Neuroscience & Biobehavioral Reviews, 31(3), 377-395. DOI: 10.1016/j.neubiorev.2006.10.004
  • Liang, X., Li, R., Wong, S. H., Sum, R. K., Wang, P., Yang, B., & Sit, C. H. (2022). The effects of exercise interventions on executive functions in children and adolescents with autism spectrum disorder: A systematic review and meta-analysis. Sports Medicine, 52(1), 75-88. DOI: 10.1007/s40279-021-01545-3
  • Lisman, J., & Buzsáki, G. (2008). A neural coding scheme formed by the combined function of gamma and theta oscillations. Schizophrenia Bulletin, 34(5), 974-980. DOI: 10.1093/schbul/sbn060
  • Lisman, J. E., & Jensen, O. (2013). The theta-gamma neural code. Neuron, 77(6), 1002-1016.
  • Lord, C., Elsabbagh, M., Baird, G., & Veenstra-Vanderweele, J. (2018). Autism spectrum disorder. The Lancet, 392(10146), 508-520. doi:10.1016/s0140-6736(18)31129-2
  • Macoun, S. J., Schneider, I., Bedir, B., Sheehan, J., ve Sung, A. (2021). Pilot study of an attention and executive function cognitive intervention in children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 51, 2600-2610. DOI: 10.1007/s10803-020-04723-w
  • Magosso, E., De Crescenzio, F., Ricci, G., Piastra, S., & Ursino, M. (2019). EEG alpha power is modulated by attentional changes during cognitive tasks and virtual reality immersion. Computational intelligence and neuroscience, 2019, 7051079. https://doi.org/10.1155/2019/7051079
  • McVoy, M., Lytle, S., Fulchiero, E., Aebi, M. E., Adeleye, O., & Sajatovic, M. (2019). A systematic review of quantitative EEG as a possible biomarker in child psychiatric disorders. Psychiatry Res., 279, 331–44. DOI: 10.1016/j.psychres.2019.07.004
  • Nekar, D. M., Lee, D. Y., Hong, J. H., Kim, J. S., Kim, S. G., Seo, Y. G., ve Yu, J. H. (2022). Effects of augmented reality game-based cognitive–motor training on restricted and repetitive behaviors and executive function in patients with autism spectrum disorder. In Healthcare, 10, 10. DOI: 10.3390/healthcare10101981
  • Orekhova, E. V., Stroganova, T. A., Nygren, G., Tsetlin, M. M., Posikera, I. N., Gillberg, C., & Elam, M. (2007). Excess of high frequency electroencephalogram oscillations in boys with autism. Biological Psychiatry, 62(9), 1022-1029. https://doi.org/10.1016/j.biopsych.2006.12.029
  • Ökcün Akçamuş, M. Ç., Bakkaloğlu, H., Demir, Ş., & Bahap Kudret, Z. (2019). Otizm spektrum bozukluğunda Tekrarlayıcı Davranışlar Ölçeği-Revize Türkçe Sürümünün geçerlilik ve güvenilirlik çalışması. Anadolu Psikiyatri Dergisi, 20. Doi: 10.5455/apd.42649
  • Rafiei Milajerdi, H., Sheikh, M., Najafabadi, M. G., Saghaei, B., Naghdi, N., & Dewey, D. (2021). The effects of physical activity and exergaming on motor skills and executive functions in children with autism spectrum disorder. Games for Health Journal, 10(1), 33-42. https://doi.org/10.1089/g4h.2019.0180
  • Ray, S., Niebur, E., Hsiao, S. S., Sinai, A., & Crone, N. E. (2008). High-frequency gamma activity (80–150 Hz) is increased in human cortex during selective attention. Clinical Neurophysiology, 119(1), 116-133. https://doi.org/10.1016/j.clinph.2007.09.136
  • Salari, N., Rasoulpoor, S., Rasoulpoor, S., Shohaimi, S., Jafarpour, S., Abdoli, N., ... & Mohammadi, M. (2022). The global prevalence of autism spectrum disorder: a comprehensive systematic review and meta-analysis. Italian Journal of Pediatrics, 48(1), 112. https://doi.org/10.1186/s13052-022-01310-w
  • Schöllhörn, I., Hegen, P., & Davids, K. (2012). The nonlinear nature of learning-a differential learning approach. The Open Sports Sciences Journal, 5(1). DOI: 10.2174/1875399X01205010100
  • Schöllhorn, W. I. (2000). Practical consequences of systems dynamic approach to technique and strength training. Acta Academiae Olympique Estonia, 8, 25–37.
  • Schöllhorn, W. (1994). Comparison of biomechanical movement patterns by means of orthogonal reference functions. In ISBS-Conference Proceedings Archive.
  • Sert, G. (2020). Otizmli çocuklarda uygulanan farklılıkla öğrenme egzersizlerinin denge ve üst ekstremite koordinasyonu üzerine etkisi. Düzce Üniversitesi, Sağlık bilimleri Enstitüsü, Beden Eğitimi ve Spor Anabilim Dalı. Yüksek Lisans Tezi.
  • Shahane, V., Kilyk, A., & Srinivasan, S. M. (2024). Effects of physical activity and exercise-based interventions in young adults with autism spectrum disorder: A systematic review. Autism, 28(2), 276-300. DOI: 10.1177/13623613231169058
  • Sharma, A., & Singh, M. (2015). Assessing alpha activity in attention and relaxed state: An EEG analysis. International Conference on Next Generation Computing Technologies. 508-513. DOI: 10.1109/NGCT.2015.7375171
  • Snijders, T. M., Milivojevic, B., & Kemner, C. (2013). Atypical excitation–inhibition balance in autism captured by the gamma response to contextual modulation. NeuroImage: Clinical, 3, 65-72. DOI: 10.1016/j.nicl.2013.06.015
  • Stillman, C. M., Esteban-Cornejo, I., Brown, B., Bender, C. M., & Erickson, K. I. (2020). Effects of exercise on brain and cognition across age groups and health states. Trends in Neurosciences, 43(7), 533-543. DOI: 10.1016/j.tins.2020.04.010
  • Strofylla, G., Charitou, S., Asonitou, K., ve Koutsouki, D. (2021). Efficacy of 6-Month Adapted Aerobic Program on Motor Proficiency, BMI and Cognitive Abilities of Students with Autism Spectrum Disorder: Three Case Reports. Open Journal of Social Sciences, 9(9), 153-166. DOI: 10.4236/jss.2021.99011
  • Van Diessen, E., Senders, J., Jansen, F. E., Boersma, M., & Bruining, H. (2015). Increased power of resting-state gamma oscillations in autism spectrum disorder detected by routine electroencephalography. European Archives of Psychiatry and Clinical Neuroscience, 265, 537-540. DOI 10.1007/s00406-014-0527-3
  • Wang, Y., Sokhadze, E. M., El-Baz, A. S., Li, X., Sears, L., Casanova, M. F., & Tasman, A. (2016). Relative power of specific EEG bands and their ratios during neurofeedback training in children with autism spectrum disorder. Frontiers in Human Neuroscience, 9, 723. https://doi.org/10.3389/fnhum.2015.00723
  • Wang, J. G., Cai, K. L., Liu, Z. M., Herold, F., Zou, L., Zhu, L. N., ve Chen, A. G. (2020). Effects of mini-basketball training program on executive functions and core symptoms among preschool children with autism spectrum disorders. Brain sciences, 10(5), 263. DOI: 10.3390/brainsci10050263
  • Wantzen, P., Clochon, P., Doidy, F., Wallois, F., Mahmoudzadeh, M., Desaunay, P., ... & Guillery-Girard, B. (2022). EEG resting-state functional connectivity: evidence for an imbalance of external/internal information integration in autism. Journal of Neurodevelopmental Disorders, 14(1), 1-14. https://doi.org/10.1186/s11689-022-09456-8
  • Yano, N., & Hosokawa, K. (2023). The importance of comprehensive support based on the three pillars of exercise, nutrition, and sleep for improving core symptoms of autism spectrum disorders. Frontiers in Psychiatry, 14, 1119142. https://doi.org/10.3389/fpsyt.2023.1119142
  • Zhang, Y., Tian, H., Tao, Y., Li, Y., Wang, D., ve Qin, L. (2023). A study on the effects of three game intervention programs on executive functions of preschool autistic children. International Journal of Developmental Disabilities, 1-11. https://doi.org/10.1080/20473869.2023.2215606
  • Zhao, H. C., Lv, R., Zhang, G. Y., He, L. M., Cai, X. T., Sun, Q., ... & Fu, B. (2022). Alterations of prefrontal-posterior information processing patterns in autism spectrum disorders. Frontiers in Neuroscience, 15, 768. https://doi.org/10.3389/fnins.2021.768219
There are 62 citations in total.

Details

Primary Language English
Subjects Physical Training, Sports and Physical Activity For Disabled
Journal Section Research Article
Authors

Sevim Akşit 0000-0002-4861-2677

Bülent Ağbuğa 0000-0002-4817-198X

Project Number 2022EĞBE003
Early Pub Date September 22, 2025
Publication Date September 29, 2025
Submission Date April 23, 2025
Acceptance Date July 7, 2025
Published in Issue Year 2025 Volume: 23 Issue: 3

Cite

APA Akşit, S., & Ağbuğa, B. (2025). EFFECT OF PHYSICAL ACTIVITY INTERVENTION ON COGNITIVE DEVELOPMENT IN AUTISM SPECTRUM DISORDER. SPORMETRE Beden Eğitimi Ve Spor Bilimleri Dergisi, 23(3), 162-177. https://doi.org/10.33689/spormetre.1676676