Colonic metastasis from lung cancer: a curatively treated case report and review of the literature

Abstract

Lung cancer is the most frequent cause of cancer death in the world. Lung cancer tends to metastasize, but gastrointestinal metastasis is very rare. A 52-year old female patient; previously operated on for lung epidermoid carcinoma; admitted with anemia. A mass in the sigmoid colon was found by colonoscopy. We performed a laparoscopic resection of the sigmoid colon. The report of surgical specimen was epidermoid carcinoma. And then, the patient completed the chemotherapy. The patient is stil alive 115 months after the diagnosis of metastatic colonic epidermoid carcinoma. To our knowledge, the case we reported is the first case to cure. It is necessary to be aware that primary epidermoid carcinoma of the lung may cause gastrointestinal tract metastasis. Gastrointestinal metastasis of lung cancer, is seen in the final stages of the disease, and the prognosis is poor, however, with close follow-up, early diagnosis and surgical intervention, the survey may be extended, in our patient, as.

Keywords

• Lung cancer metastases
• Gastrointestinal metastasis
• Distant metastases

References

1. Siegel R,Ward E, Brawley O, Jemal A (2011). Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths. CA Cancer J Clin. 61(4):212-236.
2. Yang CJ, Hwang JJ, Kang WY, Chong IW, Wang TH, Sheu CC, Tsai JR, Huang MS (2006). Gastro-intestinal metastasis of primary lung carcinoma: clinical presentations and outcome . Lung Cancer 54(3):319-323.
3. Hillers TK, Sauve MD, Guyatt GH (1994). Analysis of published studies on the detection of extrathoracic metastases in patients presumed to have operable non-small cell lung cancer. Thorax 49(1):14-19.
4. Antler AS, Ough Y, Pitchumoni CS , Davidian M, Thelmo W (1982). Gastrointestinal metastases from malignant tumors of the lung. Cancer 49:170-2.
5. Rossi G, Marchioni A, Romagnani E, Bertolini F, Longo L, Cavazza A, Barbieri F (2007). Primary Lung Cancer Presenting with Gastroentestinal Tract Involvement: Clinicopathologic and Immunohistochemical Features in a Series of 18 Consecutive Cases. J Thorac Oncol. 2:115-120.
6. Ryo H, Sakai H, Ikeda T, Hibino S, Goto I, Yoneda S, No¬guchi Y (1996). Gastrointestinal metastasis from lung cancer. Nihon Kyobu Shikkan Gakkai Zasshi. 34(9):968- 972.
7. Gonzalez-Tallon AI, Vasquez-Guerrero J, Garcia-Mayor MA (2013). Colonic Metastases From Lung Carcinoma: A Case Report andReview of the Literature. Gastroenterology Research 6(1):29-33.
8. Parker NA, McBride C, Forge J, Lalich D (2019). Bowel obstruction caused by colonic metastasis of lung adenocarcinoma: a case report and literature review. World J Surg Oncol. 8;17(1):63.

9. Hirasaki S, Suziki S, Umemura S, Kamei H, Okuda M, Kudo K (2008). Asymptomatic colonic metastases from primary squamous cell carcinoma of the lung with a positive fecal occult blood test. World J Gastroenterol 14(35):5481-5483.
10. Smith HJ, Vlasak MG: Metastasis to the colon from bronchogenic carcinoma (1978). Gastrointest Radiol 2(4):393-396.
11. Sakai H, Egi H, Hinoi T, Tokunaga M, Kawaguchi Y, Shinomura M, Adachi T, Arihiro K, Ohdan H (2012). Primary lung cancer presenting with metastasis to the colon: a case report. World J Surg Oncol 28;10:127.
12. Lou HZ, Wang CH, Pan HM, Pan Q, Wang J (2014). Colonic metastasis after resection of primary squamous cell carcinoma of the lung: a case report and literature review. World J Gastroenterol 20:5930–4.
13. Carroll D, Rajesh PB (2001). Colonic metastases from primary squamous cell carcinoma of the lung. Eur J Cardiothorac Surg. 19(5):719-720.
14. Habesoglu MA, Oguzulgen KI, Ozturk C, Akyurek N, Memis L (2005). A case of bronchogenic carcinoma presenting with acute abdomen. Tuberk Toraks 53: 280-283.
15. McNeill PM, Wagman LD, Neifeld JP (1987). Small bowel metastases from primary carcinoma of the lung. Cancer 59:1486-1489.
16. Rouhanimanesh Y, Vanderstighelen Y, Vanderputte S, Cools P, Wassenaar H, Vallaeys J (2001). Intra-abdominal metastases from primary carcinoma of the lung. Acta Chir Belg 101: 300-303.
17. Kim MS, Kook EH, Ahn SH, Jeon SY, Yoon JH, Han MS, Kim CH, Lee JC (2009). Gastrointestinal metastasis of lung cancer with special emphasis on a long-term survivor after operation. J Cancer Res Clin Oncol 135(2):297-301.
18. Lee PC, Lo C, Lin MT, Liang JT, Lin BR (2011). Role of surgical intervention in managing gastrointestinal metastases from lung cancer. World J Gastroenterol 17(38):4314–4320.