Research Article
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Year 2019, Volume 1, Issue 1, 34 - 41, 30.08.2019

Abstract

References

  • Referans 1.Bedirli N, Akkaya T: Postspinal Başağrısı. Anestezi Dergisi. 2010:18(3):135-140

In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache?

Year 2019, Volume 1, Issue 1, 34 - 41, 30.08.2019

Abstract

Objectives: Postdural puncture headache (PDPH) is a complication that may arise following spinal anesthesia. We investigated whether homocysteine and C-reactive protein levels may be associated in the development of PDPH in patients that received spinal anesthesia.

Materials and Methods: In order to determine homocysteine and C-reactive protein (CRP) levels, blood samples were taken from patients before and one day following spinal anesthesia. A total of 100 male patients were enrolled in the study. The mean age of the patients was 29 years old. Out of all the patients, a total of 6 developed headaches. The Mann-Whitney U-test was used to compare homocysteine and CRP levels between patients that did and did not develop headaches.

Results: Homocysteine levels before and after the operation were higher in subjects that developed a headache as compared to patients that did not develop headaches (p<0.001). CRP levels did not differ significantly between patients with headaches and patients that did not experience them (p>0.05).

Conclusions: High blood levels of homocysteine in patients with PDPH might be used as a biomarker so to predict the development of PDPH. However, future larger, multi-center studies are needed to further elucidate this association.

References

  • Referans 1.Bedirli N, Akkaya T: Postspinal Başağrısı. Anestezi Dergisi. 2010:18(3):135-140

Details

Primary Language English
Subjects Primary Health Care
Journal Section Research Articles
Authors

Murat ŞAHİN>
AMASYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, ANESTEZİYOLOJİ VE REANİMASYON ANABİLİM DALI
0000-0003-1180-2204
Türkiye


Kemal PEKER>
SAKARYA ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, GENEL CERRAHİ ANABİLİM DALI
Türkiye


Ali Seydi BOZKURT This is me
ERZİNCAN BİNALİ YILDIRIM ÜNİVERSİTESİ, TIP FAKÜLTESİ, CERRAHİ TIP BİLİMLERİ BÖLÜMÜ, ÜROLOJİ ANABİLİM DALI
Türkiye

Supporting Institution Erzincan Binali Yıldırım Üniversitesi Bilimsel Araştırma Projesi
Project Number 2012/12.01.08
Publication Date August 30, 2019
Submission Date August 1, 2019
Acceptance Date August 29, 2019
Published in Issue Year 2019, Volume 1, Issue 1

Cite

APA Şahin, M. , Peker, K. & Bozkurt, A. S. (2019). In patients receiving spinal anesthesia, can homocysteine and C-reactive protein levels predict the development of postdural puncture headache? . Sabuncuoglu Serefeddin Health Sciences , 1 (1) , 34-41 . Retrieved from https://dergipark.org.tr/en/pub/sshs/issue/48459/599681