Naringenin Nedir?

Year 2023, Volume: 49 Issue: 2, 18 - 28, 30.10.2023

Emel Demirtaş

https://doi.org/10.35238/sufefd.1225990

Cited By: 1

Abstract

Flavonoidler, sebze ve bitkilerin çoğunda yaygın olarak gözlenen geniş bir kapsamı olan bitki besinleri sınıfıdır. Flavonoidler, çeşitli biyolojik aktiviteleri olan önemli doğal bileşiklerdir. Narenciye flavonoidleri önemli bir flavonoid serisini oluşturur. Narenciye flavonoidleri, greyfurt, limon, mandalina, misket limonu, portakal gibi turunçgillerde bulunmaktadır ve terapötik açıdan önemli bir flavanoid sınıfıdır. Narenciye besin bileşenleri, yaygın olarak Vitamin P olarak adlandırılan bir grup biyoaktif flavonoiddir ve naringenin, naringin, quercetin, diosmetin, narirutin, diosmin, nobiletin, neohesperidin, rutin, hesperidin, tangeritin vb. içerir. Naringenin (5,7,4'-trihidroksiflavanon) flavanonlar adı verilen flavonoidler sınıfına aittir. Naringenin, osteoporoz, kanser ve kardiyovasküler hastalıklarda faydalı etkilerle ilişkilidir. Naringenin'in başlıca etkileri arasında ksantin oksidaz, nikotinamid adenin dinükleotid fosfat oksidaz, lipoksijenaz ve siklooksijenaz gibi pro-oksidan enzimlerin inhibisyonu; metal iyon şelasyonu ve en önemlisi serbest radikallerin temizlenmesi yer alır.

Keywords

Naringenin, Vitamin P., flavanon

Supporting Institution

Tübitak

Project Number

121Z173

Thanks

Çalışmanın gerçekleşmesinde 121Z173 numaralı proje kapsamında maddi destek sağlayan TÜBİTAK kurumuna çok teşekkür ederim.

What is naringenin?

Abstract

Flavonoids are a broad class of phytonutrients, commonly observed in most vegetables and herbs. Flavonoids are important natural compounds with various biological activities. Citrus flavonoids form an important series of flavonoids. Citrus flavonoids are found in citrus fruits such as grapefruit, lemons, tangerines, limes, oranges and are a class of therapeutically important flavonoids. Citrus nutritional components are a group of bioactive flavonoids, commonly referred to as Vitamin P, and include naringenin, naringin, quercetin, diosmetin, narirutin, diosmin, nobiletin, neohesperidin, rutin, hesperidin, tangeritin, etc. includes. Naringenin (5,7,4'-trihydroxyflavanone) belongs to the class of flavonoids called flavanones. Naringenin is associated with beneficial effects in osteoporosis, cancer, and cardiovascular disease. The main effects of naringenin include inhibition of pro-oxidant enzymes such as xanthine oxidase, nicotinamide adenine dinucleotide phosphate oxidase, lipoxygenase and cyclooxygenase; metal ion chelation and, most importantly, scavenging of free radicals.

Keywords

Naringenin, Vitamin P., flavanone

Project Number

121Z173

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