COVİD-19 Enfeksiyonu Sonrası Ergenlerde Davranışsal, Emosyonel Problemler ve Yorgunluk: Kesitsel Bir Çalışma

Abstract

Amaç: Bu çalışma, COVİD-19 enfeksiyonu sonrası ergenlerde davranışsal, emosyonel problemler ve yorgunluk belirtilerini araştırmayı amaçlamıştır. Ayrıca, ergenlerin başlangıç inflamasyon düzeyleri ile mevcut davranış, emosyonel problemler ve yorgunluk belirtileri arasındaki ilişkiler incelenmiştir.

Gereç ve Yöntemler: Çalışmaya toplam 110 ergen (56 erkek, %50.9, yaş ortalaması 14.72 yıl) ve ebeveynleri dahil edildi. Ergenlerin psikiyatrik değerlendirmeleri hastaneden taburcu olduktan 7.31±2.35 ay sonra yapılmıştır. Ergenlerdeki davranış, emosyonel problemler, Çocuk Davranışı Kontrol Listesi (CBCL) 6-18 ebeveyn formu kullanılarak değerlendirilmiştir.

Bulgular: COVİD-19 tanı anındaki C-reaktif protein (CRP), nötrofil/lenfosit oranı (NLR), monosit/lenfosit oranı (MLR) ve sistemik immün-enflamasyon indeksi (SII) dahil olmak üzere temel inflamatuar belirteçleri geriye dönük olarak saptanmıştır. En az bir davranışsal ve emosyonel problem alanında klinik aralıkta olan ergenlerin oranı tüm örneklemde %44.5, erkeklerde %35.7 ve kızlarda %53.7 olarak bulunmuştur. Düşünce sorunları tüm örneklemde (%25.5) en sık görülen sorunlar olarak bulunurken; içe yönelim ve dışa yönelim belirtilerinin oranları sırasıyla %33.6 ve %16.4 olarak saptanmıştır. Somatik ve dikkat belirtileri kadınlarda erkeklere göre daha sık olduğu bulunmuştur. İnflamatuar belirteç düzeyleri ile davranışsal ve emosyonel problem skorları arasında korelasyon saptanmamıştır. Tüm ergenlerin %36.4’ünde yorgunluk belirtileri saptanmıştır. Yorgunluk olan ergenlerde somatik ve dikkat problemlerin daha fazla olduğu bulunmuştur.

Sonuç: Bulgularımız, COVİD-19 enfeksiyonu olan ergenlerde davranışsal, emosyonel problemler ve yorgunluk belirtileri taramasının gerekli olduğunu göstermiştir. COVİD-19 enfeksiyonu sonrası davranışsal, emosyonel problemler ile başlangıç inflamasyon seviyeleri arasında bir ilişki olup olmadığını belirlemek için izlem çalışmalarına ihtiyaç vardır.

Keywords

• COVID-19
• ruh sağlığı
• ergen
• inflamasyon
• yorgunluk

Behavioral, Emotional Problems and Fatigue in Adolescents After COVID-19 Infection: A Cross-Sectional Study

Abstract

Objective: This study aimed to investigate behavioral, emotional problems and fatigue in adolescents after COVID-19 infection. Also, we examined relationships between baseline inflammation levels, fatigue, and the current behavioral and emotional problems of adolescents.

Material and Methods: A total of 110 adolescents (56 boys, 50.9%, mean age 14.72 years) and their parents were included in the study. Psychiatric assessments of the adolescents were performed 7.31±2.35 months after discharge from hospital. Behavioral and emotional problems was assessed using the Child Behavior Checklist (CBCL) 6-18 parent-rated questionnaire.

Results: We collected baseline inflammatory markers including C-reactive protein (CRP), the neutrophil/lymphocyte ratio (NLR), the monocyte/lymphocyte ratio (MLR), and the systemic immune-inflammation index (SII). The proportions of adolescents that were in the clinical range in at least one behavioral and emotional domain were as follows: 44.5% in the entire sample, 35.7% in boys, and 53.7% in girls. Thought problems were the most common problems in the entire sample (25.5%). The rates of internalizing and externalizing symptoms were 33.6% and 16.4%, respectively. Somatic and attention symptoms were more frequent in females than in males. Inflammatory marker levels did not correlate with behavioral and emotional scores. Fatigue symptoms were determined in 36.4% of all adolescents. We found that somatic and attention problems are more common in fatigued adolescents.

Conclusion: Our findings demonstrated that screening for behavioral, emotional problems, and fatigue in adolescents with COVID-19 infection is necessary. Future studies with a follow-up design are needed to determine whether a relationship exists between behavioral, emotional problems and baseline inflammation levels after COVID-19 infection.

Keywords

• COVID-19
• Mental health
• Adolescent
• Inflammation
• Fatigue

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