Hemogram Parameters of Children with Bell’s Palsy at the Time of Admission and Their Findings in the Follow-up

Year 2024, , 295 - 299, 24.09.2024

İlknur Sürücü Kara , Yusuf Kemal Arslan

https://doi.org/10.12956/tchd.1423447

Abstract

Objective: The exact cause of idiopathic facial paralysis (Bell’s palsy) is not clear. The objective of our study was to investigate the relationship between certain hemogram parameters and the clinical prognosis in pediatric patients with facial paralysis.

Material and Methods: The files of patients with Bell’s palsy under the age of 18 who applied to our hospital were evaluated retrospectively. Leukocyte, neutrophil, lymphocyte, platelet count, red cell distribution width, neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and monocyte to lymphocyte ratio were compared between patients with Bell’s palsy and the control group. Information about their last health status recorded.

Results: A total of seventeen children with Bell’s palsy and 17 control groups were included in the study. There were 7 boys (41.20%) and 10 girls (58.70%) in each group, the mean age was 11.80±4.40 (minimum 3.0-maximum 17.9) years. While the median neutrophil-lymphocyte ratio was 1.25 (0.41-7.63) in patients with Bell’s palsy and 1.40 (0.42-2.52) in the control group, the median mean platelet volume level was 9.30 fL (8.20-12.30) in patients with Bell’s palsy and 9.95 fL (9.30-11.70) in the control group, and the median red cell distribution width level was 12.75 % (11.50-26.30) in patients with Bell’s palsy and 12.70% (12.10-26.30) in the control group. None of them were statistically significant. There were six patients with Bell’s palsy with low mean platelet volume levels and no patients with low mean platelet volume levels in the control group (p=0.007). There was a positive correlation between the neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and monocyte-lymphocyte ratio and the recovery time of patients with Bell’s palsy.

Conclusion: Bell’s palsy may show a better prognosis in girls. High neutrophil-lymphocyte ratio, platelet-lymphocyte ratio, and monocyte-lymphocyte ratio may be indicators of delayed recovery, inflammation, and microvascular ischemia in Bell’s palsy.

Keywords

Bell’s palsy, Child, Blood Cell Count, Inflammation

Ethical Statement

Erzincan Binali Yıldırım University Clinical Research Ethics Committee Chairman (The university medical sciences ethics committee gave permission for the study with the decision numbered 32/11 taken at the session numbered 32. Date: 16/10/2018) This study was conducted in accordance with the Declaration of Helsinki.

Supporting Institution

Yok

Project Number

Proje numarası yok

Thanks

I would like to thank all my colleagues who supported our work.

Bell Paralizisi Tanılı Çocukların Başvuru Anında Hemogram Parametreleri ve İzlemdeki Bulguları

Abstract

Amaç: İdiopatik fasiyal paralizinin (Bell paralizisi) kesin sebebi belli değildir. Çalışmamızda fasiyal paralizi tanılı çocuk hastalarda, bazı hemogram parametreleri ile klinik prognoz arasında ilişki olup olmadığının araştırılması amaçlandı.

Gereç ve Yöntemler: Hastanemize başvuran 18 yaş altındaki Bell paralizi tanılı hasta dosyaları retrospektif değerlendirildi. Lökosit, nötrofil, lenfosit, trombosit sayısı, kırmızı hücre dağılım genişliği, nötrofil lenfosit oranı, trombosit lenfosit oranı ve monosit lenfosit oranı, Bell paralizili hastalar ile kontrol grubu arasında karşılaştırıldı. Son sağlık durumlarıyla ilgili bilgiler kaydedildi.

Bulgular: Toplam on yedi Bell paralizi tanılı çocuk ve 17 kontrol grubu çalışmaya dahil edildi. Her bir grupta 7 erkek (%41.20), 10 kız (%58.70) vardı, yaş ortalaması 11.80±4.40 (minimum 3.00-maximum 17.90) yıldı. Bell paralizili hastalarda nötrofil lenfosit oranı medyanı 1.25 (0.41-7.63) iken kontrol grubunda nötrofil lenfosit oranı 1.40 (0.42-2.52), medyan ortalama trombosit hacim düzeyi Bell paralizili hastalarda 9.30 fL (8.20-12.30), kontrol grubunda 9.95 fL (9.30-11.70); medyan kırmızı hücre dağılım genişliği, Bell paralizili hastalarda 12.75 % (11.50-26.30) ve kontrol grubunda 12.70 % (12.10-26.30)’du. İstatistiksel olarak hiçbiri anlamlı değildi. Ortalama trombosit hacim düşüklüğü olan altı Bell paralizili hasta vardı, kontrol grubunda ortalama trombosit hacmi düşüklüğü olan kişi yoktu (p=0.007). Bell paralizili hastaların iyileşme süresi ile nötrofil lenfosit oranı, trombosit lenfosit oranı, monosit lenfosit oranı arasında pozitif korelasyon vardı.

Sonuç: Bell paralizisi kızlarda daha iyi prognoz gösterebilir. Nötrofil lenfosit oranı, trombosit lenfosit oranı ve monosit lenfosit oranı yüksekliği Bell paralizisinde iyileşmede gecikme, inflamasyon ve mikrovasküler iskeminin bir göstergesi olabilir.

Keywords

Bell Paralizisi, Çocuk, Tam Kan Sayımı, İnflamasyon

Project Number

Proje numarası yok

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