Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy

Volume: 11 Number: 1 April 1, 2017
  • Ulaş Emre Akbulut
  • Elif Sağ
  • Murat Çakır
TR EN

Özofagogastroduodenoskopi Yapılmış Çocuklarda Özofagus Patolojilerinin Değerlendirilmesi

Abstract

Amaç: Çocuklarda özofagus patolojilerinin sıklığı, bu hastalıkların yaş, cinsiyet ve semptomlarla ilişkisini içeren veriler sınırlıdır. Çalışmanın amacı, çocuklardaki özofagus patolojilerinin sıklığının, etiyolojisinin, endoskopik ve histopatolojik özelliklerinin incelenmesidir.Gereç ve Yöntemler: Birimimizde Mayıs 2009 - Haziran 2015 tarihleri arasında özofagogastroduodenoskopi yapılmış 1-17 yaş aralığında hastalar retrospektif olarak incelendi (n=3081). Hastaların dosya bilgilerinden yaşı, cinsiyeti, şikayetleri ve endoskopik bulguları kaydedildi. İstatiksel değerlendirmede iki grup karşılaştırmalarında normal dağılım gösteren değişkenler için Bağımsız İki Örnek t testi, normal dağılım göstermeyen değişkenler için Mann-Whitney U testi, kategorik değişkenlerin karşılaştırılmasında Ki-kare testi kullanıldı.Bulgular: Toplam 335 hastanın (%10.8) özofagusunda patoloji mevcuttu (205 hastada endoskopik, 12 hastada histopatolojik, 118 hastada hem endoskopik hem de histopatolojik). On yaşının üzerindeki hastalarda özofagus patolojisinin daha sık görüldüğü tespit edildi (p<0.001, OR: 1.65, %95 CI: 1.31-2.08). Reflü şikayeti (89 hasta, %26.5, p<0.001, OR: 7.58, %95 CI: 5.61-10.25) ve disfajisi (10 hasta, %2.9, p<0.001, OR: 7.01, %95 Cl: 3.00-16.35) olan hastalarda özofagusta patoloji saptanma oranının daha fazla olduğu saptandı. Hiatal hernisi olan tüm hastalarda (n=8) histopatolojik anormallik bulunurken, endoskopik olarak yüksek evre özofajit olanlarda daha sık histopatolojik anormallik olduğu tespit edildi.Sonuç: Çalışmamızda, 10 yaşın üzerinde, reflü şikayetleri ve disfajisi olan hastalarda özofagogastroduodenoskopinin tanısal önemi olduğu ve endoskopik olarak saptanan yüksek evre özofajit ile hiatal herni varlığında histopatolojik anormalliğin daha sık olduğu tespit edilmiştir.

Keywords

References

  1. Noble AJ, Drouin E, Tamblyn R. Design of predictive models for positive outcomes of upper and lower gastrointestinal endoscopies in children and adolescents. J Pediatr Gastroenterol Nutr 2008;46: 409-13.
  2. Liacouras CA, Furuta GT, Hirano I, Atkins D, Attwood SE, Bonis PA, et al. Eosinophilic esophagitis: Updated consensus recommendations for children and adults. J Allergy Clin Immunol 2011;128:3-20.
  3. Dahms BB. Reflux esophagitis: Sequelae and differential diagnosis in infants and children including eosinophilic esophagitis. Pediatr Dev Pathol 2004;7:5-16.
  4. Dent J. Microscopic esophageal mucosal injury in nonerosive reflux disease. Clin Gastroenterol Hepatol 2007;5:4-16.
  5. Chadwick LM, Kurinczuk JJ, Hallam LA, Brennan BA, Forbes D. Clinical and endoscopic predictors of histological oesophagitis in infants. J Paediatr Child Health 1997;33:388-93.
  6. Gordon C, Kang JY, Neild PJ, Maxwell JD. The role of the hiatus hernia in gastro-oesophageal reflux disease. Aliment Pharmacol Ther 2004;20:719-32.
  7. Scarpato E, D’Armiento M, Martinelli M, Mancusi V, Campione S, Alessandrella A, et al. Impact of hiatal hernia on pediatric dyspeptic symptoms. J Pediatr Gastroenterol Nutr 2014; 59:795-8.
  8. Ruigo`mez A, Wallander MA, Lundborg P, Johansson S, Rodriguez LA. Gastroesophageal reflux disease in children and adolescents in primary care. Scand J Gastroenterol 2010;45:139–46.

Details

Primary Language

English

Subjects

-

Journal Section

-

Authors

Ulaş Emre Akbulut This is me

Elif Sağ This is me

Murat Çakır This is me

Publication Date

April 1, 2017

Submission Date

April 1, 2017

Acceptance Date

-

Published in Issue

Year 2017 Volume: 11 Number: 1

APA
Akbulut, U. E., Sağ, E., & Çakır, M. (2017). Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy. Türkiye Çocuk Hastalıkları Dergisi, 11(1), 9-14. https://izlik.org/JA74FE73PT
AMA
1.Akbulut UE, Sağ E, Çakır M. Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy. Turkish J Pediatr Dis. 2017;11(1):9-14. https://izlik.org/JA74FE73PT
Chicago
Akbulut, Ulaş Emre, Elif Sağ, and Murat Çakır. 2017. “Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy”. Türkiye Çocuk Hastalıkları Dergisi 11 (1): 9-14. https://izlik.org/JA74FE73PT.
EndNote
Akbulut UE, Sağ E, Çakır M (April 1, 2017) Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy. Türkiye Çocuk Hastalıkları Dergisi 11 1 9–14.
IEEE
[1]U. E. Akbulut, E. Sağ, and M. Çakır, “Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy”, Turkish J Pediatr Dis, vol. 11, no. 1, pp. 9–14, Apr. 2017, [Online]. Available: https://izlik.org/JA74FE73PT
ISNAD
Akbulut, Ulaş Emre - Sağ, Elif - Çakır, Murat. “Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy”. Türkiye Çocuk Hastalıkları Dergisi 11/1 (April 1, 2017): 9-14. https://izlik.org/JA74FE73PT.
JAMA
1.Akbulut UE, Sağ E, Çakır M. Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy. Turkish J Pediatr Dis. 2017;11:9–14.
MLA
Akbulut, Ulaş Emre, et al. “Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy”. Türkiye Çocuk Hastalıkları Dergisi, vol. 11, no. 1, Apr. 2017, pp. 9-14, https://izlik.org/JA74FE73PT.
Vancouver
1.Ulaş Emre Akbulut, Elif Sağ, Murat Çakır. Evaluation of Esophageal Pathology in Children Who Underwent Esophagogastroduodenoscopy. Turkish J Pediatr Dis [Internet]. 2017 Apr. 1;11(1):9-14. Available from: https://izlik.org/JA74FE73PT


The publication language of Turkish Journal of Pediatric Disease is English.


Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.


The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.