Enfektif Endokarditli Bir Olguda Seftriakson Tedavisine Bağlı Safra Kesesinde Çoklu Taş Oluşumu

Abstract

Seftriakson, safra kesesinde geri dönüşümlü çöküntülere yol açtığı bilinen bir üçüncü kuşak sefalosporindir. Oluşturduğu bu çöküntüler biliyer pseudolithiasis olarak adlandırılır. Bu yazıda, enfektif endokardit tanısıyla seftriakson kullanılan 6 yaşında bir olgu sunulmuştur. Hastada karın ağrısı nedeniyle yapılan ultrasonografik incelemede safra kesesinde çoklu taşlar gözlenmiş ve seftriakson tedavisinin kesilmesiyle semptomlar kaybolmuş ve safra kesesindeki taşların sayı ve büyüklüğünde belirgin derecede azalma gözlenmiştir. Çocukluklarda sıklıkla kullanılan seftriakson tedavisi sırasında safra taşlarının gelişebileceği ve bu taşların cerrahi tedavi gerekmeden kendiliğinden gerileyebileceği vurgulanmıştır.

Keywords

• İnfektif endokardit, Kolelitiyazis, Seftriakson

Multiple Gallstone Formation due to Ceftriaxone Treatment in a Child Diagnosed with Infective Endocarditis

Abstract

Ceftriaxone, a third-generation cephalosporin, has been known to cause reversible sludge in the gallbladder. This sludge is referred to as biliary pseudolithiasis. In this article, a six-year-old child diagnosed with infective endocarditis is presented. He suffered from abdominal pain during the treatment with ceftriaxone and we performed an abdominal ultrasonographic examination that revealed multiple stones in the gallbladder. His symptoms quickly disappeared after the cessation of the treatment with ceftriaxone and we observed a significant decrease in size and number of the gallstones. Ceftriaxone is a commonly used drug in childhood and may cause gallstone formation. These gallstones usually resolve spontaneously and do not necessitate any surgical procedure

Keywords

• Infective endocarditis, Cholelithiasis, Ceftriaxone

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