Yenidoğan Döneminde Geçici İzole Sağ Ventrikül Hipertrofisi

Abstract

Yenidoğan döneminde geçici hipertrofik kardiyomiyopati nadir görülmektedir. Term olarak dünyaya gelen ve yaşamının üçüncü gününde yapılan ekokardiyografik inceleme ile sağ ventrikül hipertrofisi tespit edilen bir yenidoğan olgusu sunulmuştur. Rutin takiplerinde ilginç bir şekilde 10 hafta içinde hipertrofinin herhangi bir tedavi uygulanmadan kendiliğinden düzeldiği görüldü. Geçici sağ ventrikül hipertrofisi pediatrik kardiyoloji literatüründe yeterince yer almamıştır. Gebelik süresince polifenol içeriği yüksek besinlerin tüketiminin duktusun erken kapanmasına neden olduğu bilinmektedir. Olgumuzda görülen sağ ventrikül hipertrofisi duktus arteriyozusun erken kapanmasına bağlı gelişmiş olabilir. Geçici sağ ventrikül hipertrofisi nadir görülmesi nedeniyle ve annelerin gebelik döneminde intrauterin duktusun erken kapanmasına neden olabilecek besinler yönünden dikkatli olunması gerektiğini vurgulamak amacıyla bu olgu sunulmuştur.

Keywords

• Duktus arteriozus, Hipertrofi, Yenidoğan, Sağ ventrikül

Transient Isolated Right Ventricular Hypertrophy in a Neonate

Abstract

Transient hypertrophic cardiomyopathy is rarely seen in neonates. We have reported a term neonate with transient right ventricular hypertrophy, diagnosed with echocardiographic investigation on the third day of life and interestingly disappeared within 10 weeks without any specific treatment. Transient right ventricular hypertrophy has not attracted enough attention in the pediatric cardiologic literature. It is well known that during pregnancy, maternal consumption of polyphenol-rich substances may cause fetal ductal constriction. In our case, this anomaly might be due to premature closure of ductus arteriosus. We have reported such a case because of the rarity of this anomaly and we wanted to attract attention about the nutrition of pregnant women

Keywords

• Ductus arteriosus, Hypertrophy, Newborn, Right ventricular

References

1. Towbin JA, Lipshultz SE. Genetics of neonatal cardiomyopathy. Curr Opin Cardiol 1999;14:250-62.
2. Vaillant MC, Chantepie A, Casasoprana A, Chamboux C, Suc AL, Gold F, et al. Transient hypertrophic cardiomyopathy in neonates after acute fetal distress. Pediatr Cardiol 1997;18:52-6.
3. Werner JC, Sicard RE, Hansen TW, Solomon E, Cowett RM, Oh W. Hypertrophic cardiomyopathy associated with dexamethasone therapy for bronchopulmonary dysplasia. J Pediatr 1992;120(2 Pt 1):286-91.
4. Akcoral A, Oran B, Tavli V, Oren H, Cevik NT. Transient right sided hypertrophic cardiomyopathy in an infant born to a diabetic mother. Indian J Pediatr 1996;63:700-3.
5. Luchese S, Manica JL, Zielinsky P. Intrauterine ductus arteriosus constriction: Analysis of a historic cohort of 20 cases. Arq Bras Cardiol 2003;81:405-10.
6. Trevett TN Jr, Cotton J. Idiopathic constriction of the fetal ductus arteriosus. Ultrasound Obstet Gynecol 2004;23:517-9.
7. Long WE, Wilson AD, Srinivasan S, Seeger KJ, Maginot KR. In utero premature closure of the ductus arteriosus presenting as isolated RVH. WMJ 2009;108:370-2.
8. Tomar M, Radhakrishnan S, Shrivastava S. Transient severe isolated RVH in neonates. Cardiol Young 2003;13:384-6.

9. Mielke G, Steil E, Gonser M. Prenatal diagnosis of idiopathic stenosis of the ductus arteriosus associated with fetal atrial flutter. Fetal Diagn Ther 1997;12:46-9.
10. Mielke G, Gonser M. Closure of the human fetal ductus arteriosus (Letter). Am J Obstet Gynecol 1997;176:495-6.
11. Van Marter LJ, Leviton A, Allred EN, Pagano M, Sullivan KF, Cohen A, et al. Persistent pulmonary hypertension of the newborn and smoking and aspirin and nonsteroidal antiinflammatory drug consumption during pregnancy. Pediatrics 1996;97:658–63.
12. Boeuf B, Maragnes P, Belzic I, Lacotte J, Bonte JB, Guillois B. Glucocorticoid-induced hypertrophic cardiomyopathy in premature infants: Apropos of 4 cases. Arch Pediatr 1997;4:152-7.
13. Sciacca P, Romeo MG, Falsaperla R, Mattia C, Betta P, Tornambene G, et al. Transient RVH in a newborn infant exposed in utero to nimesulide. Minerva Pediatr 2005;57:313-8.
14. Schiessl B, Schneider KT, Zimmermann A, Kainer F, Friese K, Oberhoffer R. Prenatal constriction of the fetal ductus arteriosus- -related to maternal pain medication? Z Geburtshilfe Neonatol 2005;209:65-8.
15. Zielinsky P, Piccoli AL Jr, Manica JL, Nicoloso LH. New insights on fetal ductal constriction: Role of maternal ingestion of polyphenol- rich foods. Expert Rev Cardiovasc Ther 2010;8:291-8.
16. Zielinsky P, Manica JL, Piccoli Jr A, et al. Ductal flow dynamics right ventricular size are influenced by maternal ingestion of polyphenol- rich common beverages in normal pregnancies. Ultrasound Obstet Gynecol 2007;30:397.