Kawasaki Hastalığı Olgularımızın Değerlendirilmesi

Abstract

Giriş: Kawasaki hastalığı etyolojisi tam olarak bilinmeyen akut febril sistemik bir vaskülittir. Gelişmiş ülkelerde en sık edinsel kalp hastalığı nedenidir. Çalışmamızın amacı Kawasaki hastalığı tanısı alan hastalarımızın klinik farklılıklarını gözden geçirmektir.Metod: Aralık 2004 – Ocak 2009 tarihleri arasında hastanemizde Kawasaki hastalığı tanısı alıp, tedavi edilen hastaların demografik, klinik, laboratuvar ve tedavi sonuçları retrospektif olarak değerlendirildi.Bulgular: Kawasaki hastalığı tanısı alan 35 hastanın 10’u kız (% 28.6), 25’i erkek (%71.4) olup erkek/kız oranı 2.5, yaş ortancası 4 yıl olarak bulundu. Hastalarda ateşe en sık eşlik eden bulgular olarak deri döküntüsü (% 88.6) saptandı. Üç hastada (% 8.6) koroner arter anomalisi tespit edildi. Hastaların % 51.4’ü klasik, %48.6’sı inkomplet Kawasaki hastalığı tanısı aldı. Konjonktivit, orofarenks ve periferal ekstremite değişiklikleri klasik Kawasaki hastalığı grubunda daha yüksek oranda bulunmakla birlikte sadece periferal ekstremite değişiklikleri yönünden istatistiksel olarak anlamlı fark bulundu (p=0.041). Her iki grup arasında yaş, cinsiyet, ateş süresi, İVİG tedavisi alma zamanı, kan sayımı ve akut faz reaktanları yönünden bir fark gözlenmedi (p>0.05).Sonuç: Kawasaki hastalığında mortalite ve morbiditenin başlıca nedeni olan kardiyovasküler komplikasyonların önlenmesi için tanı ve tedavisinin zamanında yapılması önemlidir.

Keywords

• Kawasaki hastalığı, klasik form, inkomplet form

EVALUATION OF CHILDREN WITH KAWASAKI DISEASE

Abstract

Background: Kawasaki disease (KD) is a febrile systemic vasculitis of childhood and its etiology remains unknown. The leading cause of KD is acquired heart disease in developed countries. The aim of this study is to describe clinical and epidemiological characteristics of children with Kawasaki disease in our hospital.Material and method: Between December 2004 and January 2009; the medical records of the patients treated for KD at Dr. Sami Ulus Children’s Training and Research Hospital were reviewed retrospectively fort this study.Results: Thirty five patients were diagnosed as having Kawasaki disease in our center. Male to female ratio was 2.5. The median age at diagnosis was 4 years. Skin rash (88.6%) was the leading accompying finding to fever. Coronary artery anomaly was detected in 3 (8.6%) patients. Classical KD and incomplete KD was found in 51.4% and 48.6% of the patients, respectively. Although conjunctivitis, oropharyngeal and peripheral extremity findings were more common in the classical KD group, the difference was statistically significant for only peripheral extremity findings between classical and incomplete KD groups (p=0.041). Age, gender, duration of fever, time for IVIG treatment, and laboratory findings were not different between two groups (p>0.05). Conclusion: Early diagnosis and appropriate treatment of KD is important in terms of avoiding the cardiovascular complications; the leading cause of mortality and morbidity

Keywords

• Kawasaki disease, classical form, incomplete form

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