Bir Adolesanda Memede Cystosarcoma Phyllodes: Olgu Sunumu

Abstract

Cystosarcoma phyllodes (CP) çocuklarda nadir görülür. Bu olgu sunumunda 13 yaşında bir kız çocuğunda memenin CP tümörü tanımlandı. Klinik muayenede hızlı olarak büyüyen ağrısız tümör mevcuttu. Kitle çıkarıldıktan sonra yapılan histolojik incelemede hiperselüler stroma ve stroma içine uzanan yaprak benzeri glandlar saptandı. Cystosarcoma phyllodesin tek etkili tedavisi, normal meme dokusu sınırlarının sağlandığı geniş cerrahi eksizyondur.

Keywords

• Cystosarcoma Phyllodes, meme, tümör, adolesan

CYSTOSARCOMA PHYLLODES IN THE BREAST OF AN ADOLESCENT: A CASE REPORT

Abstract

Cystosarcoma phyllodes (CP) is an uncommon tumor in children. In this case report, the authors describe a case of cystosarcoma phylloides of the breast in a 13-year-old girl. The clinical examination showed a voluminous painless tumour which had grown rapidly. The mass was removed. The histologic examination confirmed a hypercellular stroma and glandular elements projecting into the stroma in a leaf-like fashion. The only effective therapy of Cystosarcoma phyllodes is wide surgical removal with an adequate margin of normal breast tissue

Keywords

• Cystosarcoma phyllodes, breast, tumor, adolescent

References

1. Davıd AJ, Kulıg JW. Adolescent breast disorders. Adolesc Health Uptake 1996; 9:1-8.
2. Jimerson GK. The adolescent breast:disorders and evaluation. Medical Aspects of Human Sexuality 1985;19:66.
3. Neinstein LS. Breast disease in adolescents and young women. Ped Clin North Am 1999;46:607-629.
4. Vorherr H, Vorherr UF, Kutvirt DM, Key CR. Cystosarcoma phyllodes: epidemiology, pathohistology, pathobiology, diagnosis, therapy, and survival. Arch Gynecol 1985;236:173-181.
5. Cheng SP, Chang YC, Liu TP, Lee JJ, Tzen CY, Liu CL. Phyllo- des tumor of the breast: the challenge persists. World J Surg ;30:1414-1421.
6. Buchanan EB. Cystosarcoma phyllodes and its surgical manage- ment. Am Surg 1995;61:350–355.
7. Reinfuss M, Mituś J, Duda K, Stelmach A, Ryś J, Smolak K. The treatment and prognosis of patients with phyllodes tumor of the breast: an analysis of 170 cases. Cancer 1996;77:910-916.
8. Chaney AW, Pollack A, McNeese MD, Zagars GK, Pisters PW, Pollock RE, Hunt KK. Primary treatment of cystosarcoma phyllodes of the breast. Cancer 2000;89:1502-1511.

9. Chen WH, Cheng SP, Tzen CY, Yang TL, Jeng KS, Liu CL, Liu TP. Surgical treatment of phyllodes tumors of the breast: retrospecti- ve review of 172 cases. J Surg Oncol 2005;91:185-194.
10. Liang MI, Ramaswamy B, Patterson CC, McKelvey MT, Gordillo G, Nuovo GJ, Carson WE 3rd. Giant breast tumors: Surgical ma- nagement of phyllodes tumors, potential for reconstructive sur- gery and a review of literature. World J Surg Oncol 2008;6:117.
11. Blumencranz PW, Gray GF. Cystosarcoma phyllodes. Clinical and pathologic study. NY State J Med 1978;78:623–627.
12. Hart WR, Bauer RC, Oberman HA. Cystosarkoma phyllodes: Clinico-pathologic study of 26 hypercellular periductal stromal tumours of the breast. Am J Clin Pathol 1978; 70: 211-216.
13. McDivitt RW, Urban JA, Farrow JH. Cystosarkoma phyllodes. John Hopkins Med J 1967; 120: 33-45.
14. Treves N, Sunderland DA. Cystosarkoma phyllodes of breast: a malignant and benign tumor;a clinicopathologic study of seventy cases. Cancer 1951; 4: 1286-332.
15. Rajan PB, Cranor ML, Rosen PP. Cystosarcoma phyllodes in ado- lescent girls and young women: a study of 45 patients. Am J Surg Pathol 1998;22:64–69.
16. Inder M, Vaishnav K, Mathur DR. Benign breast lesions in pre- pubertal female children--a study of 20 years. J Indian Med Assoc ;99:619–620. Karakoyunlar Ö, Tanır N, Zengel B, Selek E, Deneçli GA. Phyllo