Application of Screening Tests in Diagnosis of Gestational Diabetes Mellitus

Year 2019, , 489 - 491, 23.12.2019

Çiğdem Yücel , Andaç Onur Sebla Ertuğrul Müjgan Ercan , Murat Kızılgün Turan Turhan

https://doi.org/10.12956/tchd.628264

Abstract

Background: Gestational
Diabetes Mellitus (GDM) is defined as the glucose intolerance started or
diagnosed first at pregnancy. GDM screening tests are applied as single or
two-step tests. The aim of the present study is to evaluate the numbers and
positiveness ratios of single or two-step screening tests.

Materials and Methods:
The number of GDM screening test pregnant women applied to Ankara Numune
training and Research Hospital Biochemistry Clinic between years 2010-2014 were
evaluated from Hospital Laboratory Information System retrospectively, and
applied numbers of one and two step screening tests and positiveness ratios
were evalauted fort his 5 year period.

Results:
281 (18,5%) of the total 1514 tests were positive. 270 (96,1%) of this positive
results were obtained by one-step test and 11 (3,9%) of them were obtained by
two-step test. In year 2011, all screening tests were carried out by one-step
approach. In years 2012-2014, single step approach was appplied in increasing
ratios. GDM detection rate of sinle-step test was found to be higher than
two-step test.

Conclusion:
Single step approach can be the test of choice for GDM screening as it has a
higher detection rate and more comfortable fort he patient.

Keywords

Gestational Diabetes Mellitus, Oral Glucose Tolerance Test

Gestasyonel Diyabetes Mellitus Tanısında Tarama Testlerinin Uygulanma Oranı

Abstract

Amaç: Gestasyonel
Diyabetes Mellitus (GDM), ilk defa gebelikte başlayan veya teşhis edilen glukoz
intoleransıdır.. GDM tarama testleri tek veya iki aşamalı uygulanabilmektedir. Bu
çalışmanın amacı, , tek ve iki aşamalı tarama test sayılarının ve
pozitiflik oranlarını karşılaştırmalı olarak değerlendirmektir.

Gereç
ve yöntem: Çalışmada 2010-2014 yılları arasında Ankara
Numune Eğitim ve Araştırma Hastanesi Tıbbi Biyokimya Kliniği’ne GDM tarama
testi için başvuran gebelere yapılan Oral Glukoz Tolerans Testi (OGTT) sayıları
HBYS üzerinden taranmış,  İki aşamalı
tarama testi (50g ve 100g) ile tek aşamalı (75g) tarama protokollerinin yıllara
göre değişen sayıları ve pozitiflik oranları 5 yıllık süreçte retrospektif
olarak incelenmiştir.

Bulgular: Yapılan
toplam 1514 testin 281’i (%18,5) pozitiftir. Pozitif sonuçların 270’i (%96,1)
tek aşamalı, 11’i (%3,9) iki aşamalı test ile elde edilmiştir.  2011 yılında tüm tarama testleri tek aşamalı
olarak yapılmıştır. 2012-2014 yıllarında tek aşamalı test giderek artan
oranlarla uygulanmıştır. Tek aşamalı testin GDM tespit oranları iki aşamalı
teste göre daha yüksek bulunmuştur.

Sonuç: Gebelerde
GDM’yi yüksek oranda saptaması ve hasta açısından daha rahat olması nedeniyle
tek aşamalı tarama testi tercih edilmelidir.

Keywords

Gestasyonel Diyabetes Mellitus, Oral Glukoz Tolerans Testi

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