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Rektal Midazolam Sedasyonunun Çocuklarda Sistometrik Parametrelere Etkisi

Year 2018, Volume: 12 Issue: 3, 163 - 167, 01.12.2018

Abstract

Amaç: Çalışmamızda retrospektif olarak sistometri uygulamasından önce sedasyon verilen ve verilmeyen olgular karşılaştırılarak rektal midazolam sedasyon uygulamasının ürodinamik sistometri uygulaması üzerine etkilerinin incelenmesi amaçlandı.Gereç ve Yöntemler: Hastane kayıtlarından 01 Ocak 2014 ile 31 Aralık 2016 tarihleri arasında midazolam uygulaması yapılan ve yapılmadan sistometri gerçekleştirlen 20 olgu geriye doğru değerlendirilerek incelemeye alındı. Bu hastalarda sedasyonlu ve sedasyonsuz sistometri ölçümleri karşılaştırıldı.Bulgular: Çalışmamızda 20 olgu (15 kız, 5 erkek) değerlendirmeye alındı. Ortalama yaş 8.65±2.56 yaşdı. Bu hastalarda sedasyon yapılarak ve yapılmadan gerçekleştirilen sistometri sonuçları karşılaştırıldığında tüm parametrelerde anlamlı bir fark bulunmadı (p>0.01). Hasta ebeveynlerinin sedasyon uygulamasından memnuniyeti sorgulandığında gruplar arasında istatistiksel olarak anlamlı fark olduğu görüldü (p>0.01).Sonuç: Sistometri esnasında özellikle küçük yaş grubunda rektal midazolam uygulamasının güvenli, etkili ve uygun bir seçenek olduğuna inanmaktayız. Çalışmamızda midazolamın sistometri verilerin üzerinde herhangi bir etkisi bulunmamıştır.

References

  • Phillips D, Watson AR, Collier J. Distress and radiological investiga- tions of the urinary tract in children. Eur J Pediatr 1996;155:684-7.
  • Herd DW, McAnulty KA, Keene NA, Sommerville DE. Conscious sedation reduces distress in children undergoing voiding cystourethrography and does not interfere with the diagnosis of vesicoureteric reflux: A randomized controlled study. Am J Roentgenol 2006;187:1621-6.
  • Goodman TR, Kilborn T, Pearce R. Warm or cold contrast medium in the micturating cystourethrogram (MCUG): Which is the best? Clinical Radiology 2003; 58: 551-4.
  • Gerard LL, Cooper CS, Duethman KS, Gordley BM, Kleiber CM. Effectiveness of lidocaine lubricant for discomfort during pediatric urethral catheterization. Journal of Urology 2003;170:564-7.
  • Butler LD, Symons BK, Henderson SL, Shortliffe LD, Spiegel D. Hypnosis reduces distress and duration of an invasive medical procedure for children. Pediatrics 2005;115:77-85.
  • Ozkurkcugil C, Ozkan L. Effects of anesthetics on cystometric parameters in female rats. Int Urol Nephrol 2010;42:909-13.
  • Ameda K, Kakizaki H, Yamashita T, Nonomura K, Shinno Y, Kemmotsu O, et al. Feasibility of urodynamic study (combined cystometry and electromyography of the external urethral sphincter) under general anesthesia in children. Int J Urol 1997;4:32-9.
  • Malinovsky JM, Le Normand L, Lepage JY, Malinge M, Cozian A, Pinaud M, et al. The urodynamic effects of intravenous opioids and ketoprofen in humans. Anesth Analg 1998;87:456-61.
  • Ceran C, Pampal A, Goktaş O, Pampal HK, Olmez E, et al. Commonly used intravenous anesthetics decrease bladder contractility: An in vitro study of the effects of propofol, ketamine and midazolam on the rat bladder. Indian J Urol 2010;26:364-8.
  • Sweeney H, Rzepski B, Hochman H, Kim C, Lerer T, Ferrer F, et al. Identifying characteristics of children requiring sedation for urodynamics. Urologic Nursing 2008;28:269-72.
  • Bozkurt P, Kilic N, Kaya G, Yeker Y, Elicevik M, Söylet Y. The effects of intranasal midazolam on urodynamic studies in children. Br J Urol 1996;78:282-6.

Effects of Rectal Midazolam Sedation on Cystometric Parameters in Children

Year 2018, Volume: 12 Issue: 3, 163 - 167, 01.12.2018

Abstract

Objective: We aimed to investigate the effects of rectal midazolam sedation on the cystometry urodynamic procedure in this study by retrospectively comparing the cases that had received and not received sedation before the cystometry procedure.Material and Methods: Twenty children who underwent cystometric evaluation with and without midazolam administration were retrospectively investigated from the hospital records between 01 January 2014 and 31 December 2016. We compared cystometry measurement values of patients with and without sedation.Results: 20 cases (15 female, 5 male) were evaluated in our study. The mean age was 8.65±2.56 years. Comparison of the cystometry results with or without sedation in this patient group revealed no significant difference between the parameters (p>0.01). The parents of the patients were asked about their satisfaction and a statistically significant difference was found between the groups (p>0.01). Conclusion: We believe that sedation with rectal midazolam is a safe, effective and convenient option during cystometry, especially in the young age group. We did not find midazolam to cause any effect on cystometry data in this study

References

  • Phillips D, Watson AR, Collier J. Distress and radiological investiga- tions of the urinary tract in children. Eur J Pediatr 1996;155:684-7.
  • Herd DW, McAnulty KA, Keene NA, Sommerville DE. Conscious sedation reduces distress in children undergoing voiding cystourethrography and does not interfere with the diagnosis of vesicoureteric reflux: A randomized controlled study. Am J Roentgenol 2006;187:1621-6.
  • Goodman TR, Kilborn T, Pearce R. Warm or cold contrast medium in the micturating cystourethrogram (MCUG): Which is the best? Clinical Radiology 2003; 58: 551-4.
  • Gerard LL, Cooper CS, Duethman KS, Gordley BM, Kleiber CM. Effectiveness of lidocaine lubricant for discomfort during pediatric urethral catheterization. Journal of Urology 2003;170:564-7.
  • Butler LD, Symons BK, Henderson SL, Shortliffe LD, Spiegel D. Hypnosis reduces distress and duration of an invasive medical procedure for children. Pediatrics 2005;115:77-85.
  • Ozkurkcugil C, Ozkan L. Effects of anesthetics on cystometric parameters in female rats. Int Urol Nephrol 2010;42:909-13.
  • Ameda K, Kakizaki H, Yamashita T, Nonomura K, Shinno Y, Kemmotsu O, et al. Feasibility of urodynamic study (combined cystometry and electromyography of the external urethral sphincter) under general anesthesia in children. Int J Urol 1997;4:32-9.
  • Malinovsky JM, Le Normand L, Lepage JY, Malinge M, Cozian A, Pinaud M, et al. The urodynamic effects of intravenous opioids and ketoprofen in humans. Anesth Analg 1998;87:456-61.
  • Ceran C, Pampal A, Goktaş O, Pampal HK, Olmez E, et al. Commonly used intravenous anesthetics decrease bladder contractility: An in vitro study of the effects of propofol, ketamine and midazolam on the rat bladder. Indian J Urol 2010;26:364-8.
  • Sweeney H, Rzepski B, Hochman H, Kim C, Lerer T, Ferrer F, et al. Identifying characteristics of children requiring sedation for urodynamics. Urologic Nursing 2008;28:269-72.
  • Bozkurt P, Kilic N, Kaya G, Yeker Y, Elicevik M, Söylet Y. The effects of intranasal midazolam on urodynamic studies in children. Br J Urol 1996;78:282-6.
There are 11 citations in total.

Details

Other ID JA95YG62SK
Journal Section Research Article
Authors

Sengül Özmert This is me

Feyza Sever

Hüseyin Tuğrul Tiryaki This is me

Publication Date December 1, 2018
Submission Date December 1, 2018
Published in Issue Year 2018 Volume: 12 Issue: 3

Cite

Vancouver Özmert S, Sever F, Tiryaki HT. Effects of Rectal Midazolam Sedation on Cystometric Parameters in Children. Türkiye Çocuk Hast Derg. 2018;12(3):163-7.


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