Abstract
Akut miyokardit genellikle viral enfeksiyonlar sonrası gelişir ve sıklıkla asemptomatik seyreder. Ancak beraberinde perikardit görülebilir. Epstein-Barr virüsü (EBV) enfeksiyonuna bağlı miyoperikardit ise oldukça nadirdir. On altı yaşında erkek hasta şiddetli göğüs ağrısı şikayeti ile başvurdu. Kardiyak enzimleri yüksek saptanan olgunun elektrokardiyografik incelemesinde yaygın elektriksel voltaj düşüklüğü, DII, DIII, aVF, V5, V6 derivasyonlarında ST-T dalga değişiklikleri mevcuttu. Ekokardiyografik değerlendirmede sol ventrikülsistolik fonksiyonları normaldi ve perikardiyal efüzyonu mevcuttu. EBV VCA IgM ve EBV PCR pozitif saptanan hastada EBV miyoperikarditi tanısı düşünüldü. Hasta intravenöz immünglobulin (IVIG) ve nonsteroid anti enflamatuvar tedavisine iyi yanıt verdi ve klinik olarak tam iyileşme görüldü. Göğüs ağrısı ile başvuran hastalarda miyoperikardit ayırıcı tanıda düşünülmeli ve myoperikarditin nadir nedenlerinden EBV enfeksiyonu da akılda tutulmalıdır.
Keywords
References
- Shauer A, Gotsman I, Keren A, Zwas DR, Hellman Y, Durst R, Admon D. Acute viral myocarditis: Current concepts in diagnosis and treatment. Isr Med Assoc 2013;15:180-5.
- Schultz JC, Hilliard AA, Cooper LT, Rihal CS. Diagnosis and treatment of viral myocarditis. Mayo Clin Proc 2009;84:1001-9.
- Sabbatani S, Manfredi R, Ortolani P, Trapani FF, Viale P. Myopericarditis during a primary Epstein-Barr virüs infection in an otherwise healthy young adult. An unusual and insidious complication. Case report and a 60-year literature review. Infez Med 2012;20:75-81.
- Cohen JI. Epstein-Barr virus infections, including infectious mononucleosis. In: Fauci AS, Braunwald E, Kasper DL (eds). Harrison’s Principles of Internal Medicine. 17th ed. New York: Mc Graw Hill, 2008:1106-8.
- Şahin A, Kecik-Boşnak V, Tekin-Şahin S, Namıduru M, Karaoğlan İ. Epstein-Barr virüsu infeksiyonu sonrası gelişen perikardit: Bir olgu sunumu. Klimik Dergisi 2016;29:91-3.
- Gonzalez Saldana N, Monroy Colin VA, Pina Ruiz G, Juarez Olguin H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes 2012;5:361.
- Park MK. Myocarditis. In: Park MK. Pediatric Cardiology for Practitioners. 5th ed. Philadelphia: Mosby Elsevier, 2008:447-9.
- Cengiz AB, Cultu-Kantaroğlu O, Secmeer G, Ceyhan M, Kara A, Gurgey A. Infectious mononucleosis in Turkish children. Turk J Pediatr 2010;52:245-54.
- Sirekbasan S, Çelik DG, Abdelkareem A, Yüksel P, Aslan M, Sarıbaş S, et al. Epstein-Barr virüsu infeksiyonu tanısında EBV IgM/IgG ve Monospot testlerinin irdelenmesi. Klimik Dergisi 2012;25:107-10.
Abstract
Acute myocarditis usually develops after viral infections and is often asymptomatic. However, pericarditis can accompany it. Myopericarditis due to Epstein-Barr virus (EBV) infection is very rare. A 16-year-old male presented with severe chest pain. Cardiac enzymes were elevated and electrocardiographic examination revealed widespread decreased voltage and ST-T changes on the DII, DIII, aVF, V5, and V6 leads. Left ventricular systolic functions were normal and pericardial effusion was present on echocardiographic evaluation. EBV-VCA IgM and EBV-PCR were positive; EBV myopericarditis was diagnosed in the patient. The patient responded well to intravenous immunoglobulin (IVIG) and nonsteroidal antiinflammatory therapy and recovered completely. Myopericarditis should be considered in the differential diagnosis while evaluating patients with chest pain. The Epstein-Barr virus should be kept in mind even though it rarely causes myopericarditis
Keywords
References
- Shauer A, Gotsman I, Keren A, Zwas DR, Hellman Y, Durst R, Admon D. Acute viral myocarditis: Current concepts in diagnosis and treatment. Isr Med Assoc 2013;15:180-5.
- Schultz JC, Hilliard AA, Cooper LT, Rihal CS. Diagnosis and treatment of viral myocarditis. Mayo Clin Proc 2009;84:1001-9.
- Sabbatani S, Manfredi R, Ortolani P, Trapani FF, Viale P. Myopericarditis during a primary Epstein-Barr virüs infection in an otherwise healthy young adult. An unusual and insidious complication. Case report and a 60-year literature review. Infez Med 2012;20:75-81.
- Cohen JI. Epstein-Barr virus infections, including infectious mononucleosis. In: Fauci AS, Braunwald E, Kasper DL (eds). Harrison’s Principles of Internal Medicine. 17th ed. New York: Mc Graw Hill, 2008:1106-8.
- Şahin A, Kecik-Boşnak V, Tekin-Şahin S, Namıduru M, Karaoğlan İ. Epstein-Barr virüsu infeksiyonu sonrası gelişen perikardit: Bir olgu sunumu. Klimik Dergisi 2016;29:91-3.
- Gonzalez Saldana N, Monroy Colin VA, Pina Ruiz G, Juarez Olguin H. Clinical and laboratory characteristics of infectious mononucleosis by Epstein-Barr virus in Mexican children. BMC Res Notes 2012;5:361.
- Park MK. Myocarditis. In: Park MK. Pediatric Cardiology for Practitioners. 5th ed. Philadelphia: Mosby Elsevier, 2008:447-9.
- Cengiz AB, Cultu-Kantaroğlu O, Secmeer G, Ceyhan M, Kara A, Gurgey A. Infectious mononucleosis in Turkish children. Turk J Pediatr 2010;52:245-54.
- Sirekbasan S, Çelik DG, Abdelkareem A, Yüksel P, Aslan M, Sarıbaş S, et al. Epstein-Barr virüsu infeksiyonu tanısında EBV IgM/IgG ve Monospot testlerinin irdelenmesi. Klimik Dergisi 2012;25:107-10.
Details
| Other ID | JA63EY25SG |
|---|---|
| Journal Section | Case Report |
| Authors | |
| Publication Date | August 1, 2018 |
| Submission Date | August 1, 2018 |
| Published in Issue | Year 2018 Volume: 12 Issue: 2 |
The publication language of Turkish Journal of Pediatric Disease is English.
Manuscripts submitted to the Turkish Journal of Pediatric Disease will go through a double-blind peer-review process. Each submission will be reviewed by at least two external, independent peer reviewers who are experts in the field, in order to ensure an unbiased evaluation process. The editorial board will invite an external and independent editor to manage the evaluation processes of manuscripts submitted by editors or by the editorial board members of the journal. The Editor in Chief is the final authority in the decision-making process for all submissions. Articles accepted for publication in the Turkish Journal of Pediatrics are put in the order of publication, with at least 10 original articles in each issue, taking into account the acceptance dates. If the articles sent to the reviewers for evaluation are assessed as a senior for publication by the reviewers, the section editor and the editor considering all aspects (originality, high scientific quality and citation potential), it receives publication priority in addition to the articles assigned for the next issue.
The aim of the Turkish Journal of Pediatrics is to publish high-quality original research articles that will contribute to the international literature in the field of general pediatric health and diseases and its sub-branches. It also publishes editorial opinions, letters to the editor, reviews, case reports, book reviews, comments on previously published articles, meeting and conference proceedings, announcements, and biography. In addition to the field of child health and diseases, the journal also includes articles prepared in fields such as surgery, dentistry, public health, nutrition and dietetics, social services, human genetics, basic sciences, psychology, psychiatry, educational sciences, sociology and nursing, provided that they are related to this field. can be published.