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Başlangıcı Süt Çocukluğu Döneminde Olan Tekrarlayan Pnömoni Nedenleri ve Risk Faktörlerinin İlk Atak Yaşı ve Atak Sıklığı Üzerine Etkisi

Year 2017, Volume: 11 Issue: 4, 243 - 247, 01.12.2017

Abstract

Amaç: Süt çocuklarında tekrarlayan pnömoni nedenlerini ve risk faktörlerinin ilk atak ve atak sıklığına etkilerini belirlemek.Gereç ve Yöntemler: İlk pnömoni atağını 1-24 ay içerisinde geçiren ve tekrarlayan pnömoni tanı kriterlerine uyan hastalar çalışmaya alındı. Pnömoni ile ilişkili olabilecek aspirasyon sendromları, konjenital bozukluklar, havayolu obstrüksiyonu, sekresyon temizleme bozuklukları, immün yetmezlik, pulmoner hemosiderozis gibi birliktelikler incelendi. Altta yatan hastalığı olan ve olmayanlar arasında risk faktörleri, ilk atak yaşı ve atak sıklığı arasında korelasyon varlığı değerlendirildi.Bulgular: Hastaların 60’ında (%33.9) konjenital bozukluklar, 55’inde (%31) aspirasyon sendromları, 19’unda (%10.8) havayolu obstrüksiyonu, 7’sinde (%4) immün yetmezlik, 4’ünde (%2.3) kistik fibrozis, 2’sinde (%1.1) pulmoner tüberküloz ve 1’inde (%0.6) pulmoner hemosiderosis saptandı. 29 (%16.3) hastada kesin etiyoloji belirlenemedi. Altta yatan nedeni belirlenemeyen hastalarda sigara dumanına maruziyet, evde ≥5 kişi bulunması, yetersiz anne sütü alımı gibi risk faktörleri pnömoni atağı sıklığı ile ilişkili bulundu. Multipl lojistik regresyon analizi ile diğer risk faktörlerinden bağımsız olarak sadece sigara dumanının pnömoni sıklığı artışı ile ilişkisi saptandı.Sonuç: Sigara dumanına maruziyet, kalabalık ev ortamı, yetersiz anne sütü alımı, altta yatan hastalığı olmayan hastalarda pnömoni atağı sıklığını artıran önemli risk faktörleridir.

References

  • Lozano R. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2095- 128.
  • Cashat-Cruz M, Morales-Aguirre JJ, Mendoza-Azpiri M. Respiratory tract infections in children in developing countries. Semin Pediatr Infect Dis 2005;16:84-92.
  • Sheares BJ. Recurrent pneumonia in children. Pediatr Ann 2002;31:109-14.

The Etiology of Recurrent Pneumonia with Onset During Infancy, and the Effect of Risk Factors on Age at First Episode and Episode Frequency

Year 2017, Volume: 11 Issue: 4, 243 - 247, 01.12.2017

Abstract

Objective: To determine the etiology of recurrent pneumonia in infants and to identify the factors associated with age at first episode and episode frequency.Material and Methods: Children that had their first episode of pneumonia at age 1-24 months and met the diagnostic criteria for RP were included in the study. Their records were screened for conditions that may have been associated with pneumonia, including aspiration syndromes, congenital disorders, airway obstruction and secretion clearance disorders, immune deficiencies, and pulmonary hemosiderosis. The correlation between risk factors, and age at first episode and the frequency of episodes were evaluated separately for patients with and without an underlying etiology.results: In all, 60 patients (33.9%) had congenital birth defects, 55 (31%) had aspiration syndrome, 19 (10.8%) had airway obstruction, 7 (4%) had immune deficiency, 4 (2.3%) had cystic fibrosis, 2 (1.1%) had pulmonary tuberculosis, and 1 (0.6%) had pulmonary hemosiderosis. Of the patients; 29 (16.3%) had no specific etiology. In the patients without a discernible underlying disorder, risk factors (a history of exposure to cigarette smoke, ≥5 household members, insufficient breastfeeding) were significantly associated with a higher frequency of pneumonia episodes. Multiple logistic regression analysis showed that exposure to cigarette smoke was a risk factor for recurrent pneumonia episodes, independent of the other risk factors evaluated conclusion: Exposure to cigarette smoke, an overcrowded household, and insufficient breastfeeding were determined to be highly probable risk factors associated with the higher frequency of episodes in the RP patients without an underlying disorder

References

  • Lozano R. Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: A systematic analysis for the Global Burden of Disease Study 2010. Lancet 2012;380:2095- 128.
  • Cashat-Cruz M, Morales-Aguirre JJ, Mendoza-Azpiri M. Respiratory tract infections in children in developing countries. Semin Pediatr Infect Dis 2005;16:84-92.
  • Sheares BJ. Recurrent pneumonia in children. Pediatr Ann 2002;31:109-14.
There are 3 citations in total.

Details

Other ID JA86FE24CR
Journal Section Research Article
Authors

Murat Çapanoğlu This is me

Pelin Zorlu This is me

Eyüp Sarı This is me

Saliha Şenel This is me

Publication Date December 1, 2017
Submission Date December 1, 2017
Published in Issue Year 2017 Volume: 11 Issue: 4

Cite

Vancouver Çapanoğlu M, Zorlu P, Sarı E, Şenel S. The Etiology of Recurrent Pneumonia with Onset During Infancy, and the Effect of Risk Factors on Age at First Episode and Episode Frequency. Türkiye Çocuk Hast Derg. 2017;11(4):243-7.


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